Results 21 to 30 of about 101 (87)
Cannabis sintético: aspectos toxicológicos, usos clínicos y droga de diseño
La planta cannabis sativa tiene un largo historial de uso en el transcurso de la humanidad y, desde hace varias décadas, se ha retomado el interés por ella debido a su potencial terapéutico relacionado con diversidad de patologías.
Andrés Felipe Casadiego-Mesa +1 more
doaj +1 more source
Many beneficial effects of herbal and synthetic cannabinoids on gut motility and inflammation have been demonstrated, suggesting a vast potential for these compounds in the treatment of gastrointestinal disorders. These effects are based on the so‐called ‘endocannabinoid system’ (ECS), a cooperating network of molecules that regulate the metabolism of ...
Rudolf Schicho, Martin Storr
wiley +1 more source
Endocannabinoid system and pregnancy [PDF]
Abstract The endocannabinoid system (eCS), is a complex system, comprising the main endogenous ligands anandamide and 2-arachidonoyl glycerol, the cannabinoid receptors CB1 and CB2 and the biosynthetic and degrading enzymes. Cumulative evidence shows that the eCS plays an important role in reproduction, from egg fertilization to ...
Correa, Fernando Gabriel +4 more
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OBJETIVO: Este artigo revisa o sistema endocanabinoide e as respectivas estratégias de intervenções farmacológicas. MÉTODO: Realizou-se uma revisão da literatura sobre o sistema endocanabinoide e a sua farmacologia, considerando-se artigos originais ou ...
Viviane M. Saito +2 more
doaj +1 more source
Endocannabinoids and Immunity [PDF]
Over the last 10 years, a great boost of knowledge accumulated on the immunomodulatory and anti-inflammatory properties of endocannabinoids (eCBs). In this scenario, these bioactive lipids, which are produced by most immune cells along with a set of receptors and enzymes that regulate their synthesis and degradation, act as secondary modulators and ...
openaire +2 more sources
Endogenous cannabinoids play an important role in the physiology and behavioral expression of stress responses. Activation of the hypothalamic-pituitary-adrenal (HPA) axis, including the release of glucocorticoids, is the fundamental hormonal response to stress. Endocannabinoid (eCB) signaling serves to maintain HPA-axis homeostasis, by buffering basal
Riebe, C., Wotjak, C.
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The Endocannabinoid System and Spermatogenesis [PDF]
Spermatogenesis is a complex process in which male germ cells undergo a mitotic phase followed by meiosis and by a morphogenetic process to form mature spermatozoa. Spermatogenesis is under the control of gonadotropins, steroid hormones and it is modulated by a complex network of autocrine and paracrine factors.
GRIMALDI, PAOLA +2 more
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Cannabinoids have been used to treat pain for many centuries. However, only during the past several decades have rigorous scientific methods been applied to understand the mechanisms of cannabinoid action. Cannabinoid receptors were discovered in the late 1980s and have been found to mediate the effects of cannabinoids on the nervous system.
J Michael Walker +2 more
wiley +1 more source
Endocannabinoids and epilepsy [PDF]
The brain endocannabinoid system (ECS) plays an essential role in regulating central physiological processes that underlie learning and memory, anxiety, depression, addiction, appetite and feeding, pain, neuronal excitability and protection. A primary mode through which the ECS functions in the brain is via its regulation of synaptic transmission ...
Robert Blair +2 more
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Endocannabinoids in the Gut [PDF]
Cannabis has been used medicinally for centuries to treat a variety of disorders, including those associated with the gastrointestinal tract. The discovery of our bodies' own "cannabis-like molecules" and associated receptors and metabolic machinery - collectively called the endocannabinoid system - enabled investigations into the physiological ...
openaire +4 more sources

