Results 271 to 280 of about 2,670,563 (294)
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Targeting Endocrine Resistance: Is There a Role for mTOR Inhibition?
Clinical Breast Cancer, 2010The phosphatidylinositol 3-kinase (PI3K)/Akt/mammalian target of rapamycin (mTOR) pathway is a critical intracellular signaling cascade that mediates both growth factor-induced proliferation and cell survival with deregulated signaling through this pathway, a feature of most cancers.
Amna, Sheri +2 more
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Response and Resistance to the Endocrine Prevention of Breast Cancer
2008The data from observational studies and clinical trials indicates that it is possible to prevent BC for prolonged periods using various endocrine manipulations. Ovarian suppression is thought to give lifelong protection and recent data indicate that the effectiveness of Tam continues after cessation of treatment at 5-8 years.
Anthony, Howell +4 more
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Glucocorticoid-resistant forms of endocrine ophthalmopathy
Russian Annals of OphthalmologyEndocrine ophthalmopathy (EO; also called Graves’ ophthalmopathy, thyroid eye disease) is a common extrathyroidal manifestation of Graves’ disease, characterized by the presence of autoimmune inflammatory process in the orbital soft tissues. The prevalence of EO is approximately 10 cases per 10.000 population, higher in individuals over 50 years old ...
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Endocrine Response to Resistance Training in Children
Pediatric Exercise Science, 2014Bareket, Falk, Alon, Eliakim
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Cancer stem cells: Culprits in endocrine resistance and racial disparities in breast cancer outcomes
Cancer Letters, 2021Eileen J Brantley +2 more
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Resistance to endocrine therapy A panel discussion
Breast Cancer Research and Treatment, 1987W L, McGuire +3 more
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ESR1 mutations—a mechanism for acquired endocrine resistance in breast cancer
Nature Reviews Clinical Oncology, 2015Rinath Jeselsohn +2 more
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Medullary thyroid carcinoma: A component of an interesting endocrine syndrome
Ca-A Cancer Journal for Clinicians, 1969Melvin A Block
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