Veterinary Clinics of North America Equine Practice, 2010 In laminitis occurring in the field, as opposed to laminitis occurring during hospitalization or severe illness, endocrinopathic laminitis is the predominant form of laminitis. Prevalent causes of endocrinopathic laminitis are ECS and EMS. Exclusion of inflammatory or weight bearing causes of laminitis and focussing on the identification and treatment ...
C M Mcgowan
exaly +5 more sources
The application of a new laminitis scoring method to model the rate and pattern of improvement from equine endocrinopathic laminitis in a clinical setting [PDF]
BMC Veterinary Research, 2021 Background Endocrinopathic, or hyperinsulinaemia-associated laminitis (HAL) is a common and debilitating equine foot disease, and although no pharmacological treatments are registered, several are under development.
A. Meier +6 more
doaj +3 more sources
Endocrinopathic Inheritance [PDF]
JAMA - Journal of the American Medical Association, 1916 n/
Irving F. Stein, Stein, Irving F.
exaly +7 more sources
The Pharmacologic Basis for the Treatment of Endocrinopathic Laminitis
Veterinary Clinics of North America Equine Practice, 2010 Although the treatment and management of laminitis in the horse requires a holistic and often multidisciplinary approach from the veterinarian, farrier, and nutritionist, this review focuses on pharmacologic interventions that might have prophylactic benefit, specifically in the horse with laminitis as a result of pituitary pars intermedia dysfunction ...
Andy E Durham
exaly +5 more sources
Presence of Myeloperoxidase in Lamellar Tissue of Horses Induced by an Euglycemic Hyperinsulinemic Clamp [PDF]
Frontiers in Veterinary Science, 2022 Laminitis is a pathology of the equine digit leading to a failure of the dermo-epidermal interface. Neutrophil activation is recognized as a major factor in SIRS-associated laminitis.
Nazare Storms +6 more
doaj +3 more sources
Effect of sirolimus on insulin dynamics in horses [PDF]
Journal of Veterinary Internal Medicine, 2023 Background Sirolimus, a mechanistic target of rapamycin inhibitor, suppresses insulin production in other species and has therapeutic potential for hyperinsulinemia in horses.
Demia J. deTonnerre +6 more
doaj +3 more sources
A review of recent developments in the pharmacological prevention and treatment of endocrinopathic laminitis [PDF]
Animal Production Science, 2020 Despite the prevalence of endocrinopathic laminitis, the pharmacologic options for preventing and treating the disease are severely limited. The present review aims to discuss the spectrum of potential therapeutic agents for the condition, ranging from ...
Melody A De Laat, M N Sillence
exaly +4 more sources
Pathology of Natural Cases of Equine Endocrinopathic Laminitis Associated With Hyperinsulinemia [PDF]
Veterinary Pathology, 2015 Laminitis in equids is a clinical syndrome usually associated with systemic disease. Endocrinopathies recently have been recognized as the most common cause of laminitis, with hyperinsulinemia playing a key role.
N. Karikoski +5 more
semanticscholar +4 more sources
Differential Proteomic Expression of Equine Cardiac and Lamellar Tissue During Insulin-Induced Laminitis [PDF]
Frontiers in Veterinary Science, 2020 Endocrinopathic laminitis is pathologically similar to the multi-organ dysfunction and peripheral neuropathy found in human patients with metabolic syndrome.
Allison Campolo +6 more
doaj +2 more sources