Results 1 to 10 of about 343,817 (360)

Live-cell imaging of endocytosed synaptophysin around individual hippocampal presynaptic active zones

open access: yesFrontiers in Cellular Neuroscience, 2023
In presynaptic terminals 4 types of endocytosis, kiss-and-run, clathrin-mediated, bulk and ultrafast endocytosis have been reported to maintain repetitive exocytosis of neurotransmitter. However, detailed characteristics and relative contribution of each
Hiromitsu Tanaka   +3 more
doaj   +1 more source

Transsynaptic N-Cadherin Adhesion Complexes Control Presynaptic Vesicle and Bulk Endocytosis at Physiological Temperature

open access: yesFrontiers in Cellular Neuroscience, 2021
At mammalian glutamatergic synapses, most basic elements of synaptic transmission have been shown to be modulated by specific transsynaptic adhesion complexes.
Sushma Dagar   +2 more
doaj   +1 more source

Role of Spectrin in Endocytosis

open access: yesCells, 2022
Cytoskeletal spectrin is found in (non)erythroid cells. Eukaryotic endocytosis takes place for internalizing cargos from extracellular milieu. The role of spectrin in endocytosis still remains poorly understood.
Donghai Li
doaj   +1 more source

Emerging roles of proximal tubular endocytosis in renal fibrosis

open access: yesFrontiers in Cell and Developmental Biology, 2023
Endocytosis is a crucial component of many pathological conditions. The proximal tubules are responsible for reabsorbing the majority of filtered water and glucose, as well as all the proteins filtered through the glomerular barrier via endocytosis ...
Min Chen   +3 more
doaj   +1 more source

The Chemical Inhibitors of Endocytosis: From Mechanisms to Potential Clinical Applications

open access: yesCells, 2023
Endocytosis is one of the major ways cells communicate with their environment. This process is frequently hijacked by pathogens. Endocytosis also participates in the oncogenic transformation. Here, we review the approaches to inhibit endocytosis, discuss
Olga Klaudia Szewczyk-Roszczenko   +8 more
doaj   +1 more source

Dynamin-Independent Mechanisms of Endocytosis and Receptor Trafficking

open access: yesCells, 2022
Endocytosis is a fundamental mechanism by which cells perform housekeeping functions. It occurs via a variety of mechanisms and involves many regulatory proteins.
Chayanika Gundu   +7 more
doaj   +1 more source

The coiled-coil domain of EHD2 mediates inhibition of LeEix2 endocytosis and signaling. [PDF]

open access: yesPLoS ONE, 2009
Endocytosis has been suggested to be crucial for the induction of plant immunity in several cases. We have previously shown that two Arabidopsis proteins, AtEHD1 and AtEHD2, are involved in endocytosis in plant systems. AtEHD2 has an inhibitory effect on
Maya Bar   +3 more
doaj   +1 more source

Clathrin-mediated endocytosis cooperates with bulk endocytosis to generate vesicles

open access: yesiScience, 2022
Summary: Clathrin-mediated endocytosis, the most prominent endocytic mode, is thought to be generated primarily from relatively flat patches of the plasma membrane.
Gianvito Arpino   +9 more
doaj   +1 more source

SNARE Proteins Synaptobrevin, SNAP-25, and Syntaxin Are Involved in Rapid and Slow Endocytosis at Synapses

open access: yesCell Reports, 2013
Rapid endocytosis, which takes only a few seconds, is widely observed in secretory cells. Although it is more efficient in recycling vesicles than in slow clathrin-mediated endocytosis, its underlying mechanism, thought to be clathrin independent, is ...
Jianhua Xu   +7 more
doaj   +1 more source

Regulation of EGFR Endocytosis by CBL During Mitosis

open access: yesCells, 2018
The overactivation of epidermal growth factor (EGF) receptor (EGFR) is implicated in various cancers. Endocytosis plays an important role in EGFR-mediated cell signaling.
Ping Wee, Zhixiang Wang
doaj   +1 more source

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