Results 1 to 10 of about 342,167 (244)
PIP5KIβ Selectively Modulates Apical Endocytosis in Polarized Renal Epithelial Cells [PDF]
, 2013 Localized synthesis of phosphatidylinositol 4,5-bisphosphate [PtdIns(4,5)P2] at clathrin coated pits (CCPs) is crucial for the recruitment of adaptors and other components of the internalization machinery, as well as for regulating actin dynamics during ...
A Benmerah +89 more
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Frontiers in Cellular Neuroscience, 2023 In presynaptic terminals 4 types of endocytosis, kiss-and-run, clathrin-mediated, bulk and ultrafast endocytosis have been reported to maintain repetitive exocytosis of neurotransmitter. However, detailed characteristics and relative contribution of each
Hiromitsu Tanaka +3 more
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Frontiers in Cellular Neuroscience, 2021 At mammalian glutamatergic synapses, most basic elements of synaptic transmission have been shown to be modulated by specific transsynaptic adhesion complexes.
Sushma Dagar +2 more
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Emerging roles of proximal tubular endocytosis in renal fibrosis
Frontiers in Cell and Developmental Biology, 2023 Endocytosis is a crucial component of many pathological conditions. The proximal tubules are responsible for reabsorbing the majority of filtered water and glucose, as well as all the proteins filtered through the glomerular barrier via endocytosis ...
Min Chen +3 more
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Role of Spectrin in Endocytosis
Cells, 2022 Cytoskeletal spectrin is found in (non)erythroid cells. Eukaryotic endocytosis takes place for internalizing cargos from extracellular milieu. The role of spectrin in endocytosis still remains poorly understood.
Donghai Li
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A Doubleheader in Endocytosis [PDF]
Neuron, 2007 Synaptojanin1 degrades the signaling lipid phosphatidylinositol-4,5-bisphosphate and facilitates compensatory endocytosis, clathrin-coat disassembly, and vesicle reavailability at active synapses. In this issue of Neuron, Mani et al. provide new information about the separate roles of synaptojanin's two phosphatase domains and its interactions with ...
George Zanazzi, Gary Matthews
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The Chemical Inhibitors of Endocytosis: From Mechanisms to Potential Clinical Applications
Cells, 2023 Endocytosis is one of the major ways cells communicate with their environment. This process is frequently hijacked by pathogens. Endocytosis also participates in the oncogenic transformation. Here, we review the approaches to inhibit endocytosis, discuss
Olga Klaudia Szewczyk-Roszczenko +8 more
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Dynamin-Independent Mechanisms of Endocytosis and Receptor Trafficking
Cells, 2022 Endocytosis is a fundamental mechanism by which cells perform housekeeping functions. It occurs via a variety of mechanisms and involves many regulatory proteins.
Chayanika Gundu +7 more
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Cold Spring Harbor Perspectives in Biology, 2013 Endocytosis entails selective packaging of cell-surface proteins, such as receptors for cytokines and adhesion components, in cytoplasmic vesicles (endosomes). The series of sorting events that determines the fate of internalized proteins, either degradation in lysosomes or recycling back to the plasma membrane, relies on intrinsic sequence motifs ...
Yosef Yarden, Ira Mellman
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The coiled-coil domain of EHD2 mediates inhibition of LeEix2 endocytosis and signaling. [PDF]
PLoS ONE, 2009 Endocytosis has been suggested to be crucial for the induction of plant immunity in several cases. We have previously shown that two Arabidopsis proteins, AtEHD1 and AtEHD2, are involved in endocytosis in plant systems. AtEHD2 has an inhibitory effect on
Maya Bar +3 more
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