Results 1 to 10 of about 361,769 (340)

Live-cell imaging of endocytosed synaptophysin around individual hippocampal presynaptic active zones

open access: yesFrontiers in Cellular Neuroscience, 2023
In presynaptic terminals 4 types of endocytosis, kiss-and-run, clathrin-mediated, bulk and ultrafast endocytosis have been reported to maintain repetitive exocytosis of neurotransmitter. However, detailed characteristics and relative contribution of each
Hiromitsu Tanaka   +3 more
doaj   +1 more source

Transsynaptic N-Cadherin Adhesion Complexes Control Presynaptic Vesicle and Bulk Endocytosis at Physiological Temperature

open access: yesFrontiers in Cellular Neuroscience, 2021
At mammalian glutamatergic synapses, most basic elements of synaptic transmission have been shown to be modulated by specific transsynaptic adhesion complexes.
Sushma Dagar   +2 more
doaj   +1 more source

Role of Spectrin in Endocytosis

open access: yesCells, 2022
Cytoskeletal spectrin is found in (non)erythroid cells. Eukaryotic endocytosis takes place for internalizing cargos from extracellular milieu. The role of spectrin in endocytosis still remains poorly understood.
Donghai Li
doaj   +1 more source

Emerging roles of proximal tubular endocytosis in renal fibrosis

open access: yesFrontiers in Cell and Developmental Biology, 2023
Endocytosis is a crucial component of many pathological conditions. The proximal tubules are responsible for reabsorbing the majority of filtered water and glucose, as well as all the proteins filtered through the glomerular barrier via endocytosis ...
Min Chen   +3 more
doaj   +1 more source

Ephective Endocytosis [PDF]

open access: yesDevelopmental Cell, 2003
Two important new reports identify endocytosis of EphB-ephrinB complexes as a mechanism for switching between cell-cell adhesion and repulsion following plasma membrane contact. Together with the previously described shedding of ephrinA following EphA engagement, these findings resolve the paradox of how an adhesive receptor-ligand interaction ...
Halford, Michael M   +2 more
openaire   +2 more sources

The Chemical Inhibitors of Endocytosis: From Mechanisms to Potential Clinical Applications

open access: yesCells, 2023
Endocytosis is one of the major ways cells communicate with their environment. This process is frequently hijacked by pathogens. Endocytosis also participates in the oncogenic transformation. Here, we review the approaches to inhibit endocytosis, discuss
Olga Klaudia Szewczyk-Roszczenko   +8 more
doaj   +1 more source

Endocytosis and Cancer [PDF]

open access: yesCold Spring Harbor Perspectives in Biology, 2013
Endocytosis entails selective packaging of cell-surface proteins, such as receptors for cytokines and adhesion components, in cytoplasmic vesicles (endosomes). The series of sorting events that determines the fate of internalized proteins, either degradation in lysosomes or recycling back to the plasma membrane, relies on intrinsic sequence motifs ...
Mellman I, Yarden Y
openaire   +2 more sources

Dynamin-Independent Mechanisms of Endocytosis and Receptor Trafficking

open access: yesCells, 2022
Endocytosis is a fundamental mechanism by which cells perform housekeeping functions. It occurs via a variety of mechanisms and involves many regulatory proteins.
Chayanika Gundu   +7 more
doaj   +1 more source

The coiled-coil domain of EHD2 mediates inhibition of LeEix2 endocytosis and signaling. [PDF]

open access: yesPLoS ONE, 2009
Endocytosis has been suggested to be crucial for the induction of plant immunity in several cases. We have previously shown that two Arabidopsis proteins, AtEHD1 and AtEHD2, are involved in endocytosis in plant systems. AtEHD2 has an inhibitory effect on
Maya Bar   +3 more
doaj   +1 more source

Clathrin-mediated endocytosis cooperates with bulk endocytosis to generate vesicles

open access: yesiScience, 2022
Summary: Clathrin-mediated endocytosis, the most prominent endocytic mode, is thought to be generated primarily from relatively flat patches of the plasma membrane.
Gianvito Arpino   +9 more
doaj   +1 more source

Home - About - Disclaimer - Privacy