CTSK plays a critical role in pulmonary fibrosis. Excessive CTSK accumulation interacts with SNX9 to enhance TGF‐β1‐induced SMAD3 activation and GLS1 expression in fibroblasts, driving glutamine metabolism for collagen biosynthesis and exacerbating pulmonary fibrosis.
Mengting Chen+10 more
wiley +1 more source
The Different Cellular Entry Routes for Drug Delivery Using Cell Penetrating Peptides. [PDF]
Okafor M+6 more
europepmc +1 more source
LincNEAT1 Encoded‐NEAT1‐31 micropeptide directly binds with Aurora‐A and enhanced AKT pathways to pormotes phagocytosis against multi cancer cells. Abstract Macrophages play vital roles in innate and adaptive immunity, and their essential functions are mediated by phagocytosis and antigen presentation.
Jie Li+8 more
wiley +1 more source
Uptake and Toxicity of Polystyrene NPs in Three Human Cell Lines. [PDF]
Męczyńska-Wielgosz S+4 more
europepmc +1 more source
Differential endocytosis of CD4 in lymphocytic and nonlymphocytic cells. [PDF]
Annegret Pelchen–Matthews+3 more
openalex +1 more source
Isolation Techniques of Micro/Nano‐Scaled Species for Biomedical Applications
Separating micro/nano‐scale bioparticles from samples is essential for disease diagnosis, prevention, and monitoring. Therefore, a comprehensive overview of the latest advanced separation technologies is provided, and characteristics and limitations based on six key performance parameters, including purity, recovery rate, throughput, resolution, size ...
Qing Lu, Zhinan Zhang, Xianting Ding
wiley +1 more source
Endocytic Pathways Unveil the Role of Syndecans in the Seeding and Spreading of Pathological Protein Aggregates: Insights into Neurodegenerative Disorders. [PDF]
Hudák A, Letoha T.
europepmc +1 more source
Tyrosine phosphorylation provides an obligatory early signal for Fc gamma RII-mediated endocytosis in the monocytic cell line THP-1. [PDF]
Soosan Ghazizadeh, Howard B. Fleit
openalex +1 more source
piR‐RCC Suppresses Renal Cell Carcinoma Progression by Facilitating YBX‐1 Cytoplasm Localization
PIWI‐interacting RNAs (piRNAs), a novel category of small non‐coding RNAs, have been implicated in the development of various diseases. This study explores the tumor‐suppressive mechanism of a downregulated piRNA (designated piR‐RCC) in renal cell carcinoma (RCC), and provides a delivery strategy targeting RCC tumor by constructing a cell membrane ...
Ruyue Wang+16 more
wiley +1 more source
Receptor-mediated endocytosis of ovalbumin by two carbohydrate-specific receptors in rat liver cells. The intracellular transport of ovalbumin to lysosomes is faster in liver endothelial cells than in parenchymal cells [PDF]
Grete M. Kindberg+3 more
openalex +1 more source