Results 31 to 40 of about 342,266 (343)

Annexins and Endocytosis [PDF]

open access: yesTraffic, 2007
Annexins are calcium‐ and phospholipid‐binding proteins that have been proposed to have multiple roles in membrane traffic. Historically, this has been based on the in vitro properties of annexins and their localization to specific membrane compartments. However, recent functional evidence supports a role for annexins in specific membrane traffic steps,
Ian J. White, Clare E. Futter
openaire   +3 more sources

Endocytosis of Coacervates into Liposomes

open access: yesJournal of the American Chemical Society, 2022
Recent studies have shown that the interactions between condensates and biological membranes is of functional importance. Here, we study how the interaction between complex coacervates and liposomes as model systems can lead to membrane deformation and endocytosis.
Tiemei Lu   +6 more
openaire   +4 more sources

Carbachol-Mediated Endocytosis of NHE3 Involves a Clathrin-Independent Mechanism Requiring Lipid Rafts and Cdc42

open access: yesCellular Physiology and Biochemistry, 2014
Background: In intestinal epithelial cells, acute regulation of the brush border Na+/H+ exchanger, NHE3, usually occurs by changes in endocytosis and/or exocytosis. Constitutive NHE3 endocytosis involves clathrin.
Nicholas C. Zachos   +4 more
doaj   +1 more source

The clathrin-binding domain of CALM-AF10 alters the phenotype of myeloid neoplasms in mice. [PDF]

open access: yes, 2012
The PICALM (CALM) gene, whose product is involved in clathrin-mediated endocytosis, has been identified in two recurring chromosomal translocations, involving either MLL or MLLT10 (AF10). We developed a mouse model of CALM-AF10(+) leukemia to examine the
Anastasi, J   +5 more
core   +2 more sources

Interaction among Saccharomyces cerevisiae pheromone receptors during endocytosis

open access: yesBiology Open, 2014
This study investigates endocytosis of Saccharomyces cerevisiae α-factor receptor and the role that receptor oligomerization plays in this process. α-factor receptor contains signal sequences in the cytoplasmic C-terminal domain that are essential for ...
Chien-I Chang   +2 more
doaj   +1 more source

Activation of endocytosis as an adaptation to the mammalian host by trypanosomes [PDF]

open access: yes, 2007
Immune evasion in African trypanosomes is principally mediated by antigenic variation, but rapid internalization of surface-bound immune factors may contribute to survival.
Field, Mark C   +4 more
core   +2 more sources

Ligation of MHC Class II Induces PKC-Dependent Clathrin-Mediated Endocytosis of MHC Class II

open access: yesCells, 2020
In addition to antigen presentation to CD4+ T cells, aggregation of cell surface major histocompatibility complex class II (MHC-II) molecules induces signal transduction in antigen presenting cells that regulate cellular functions. We previously reported
Kento Masaki   +6 more
doaj   +1 more source

Endocytic signaling in leaves and roots: same rules different players. [PDF]

open access: yes, 2012
To take up proteins and other components required by the cell, cells internalize a portion of the plasma membrane (PM), which invaginates to form a closed vesicle within the cytoplasm in a process known as endocytosis. The major plant endocytic mechanism
Craddock, Christian, Yang, Zhenbiao
core   +2 more sources

Endocytosis of nanomedicines

open access: yesJournal of Controlled Release, 2010
Novel nanomaterials are being developed to improve diagnosis and therapy of diseases through effective delivery of drugs, biopharmaceutical molecules and imaging agents to target cells in disease sites. Such diagnostic and therapeutic nanomaterials, also termed “nanomedicines”, often require site-specific cellular entry to deliver their payload to sub ...
Daria Y. Alakhova   +3 more
openaire   +4 more sources

Endocytosis of Viruses and Bacteria [PDF]

open access: yesCold Spring Harbor Perspectives in Biology, 2014
Of the many pathogens that infect humans and animals, a large number use cells of the host organism as protected sites for replication. To reach the relevant intracellular compartments, they take advantage of the endocytosis machinery and exploit the network of endocytic organelles for penetration into the cytosol or as sites of replication.
Cossart, Pascale, Helenius, Ari
openaire   +4 more sources

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