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Efficient differentiation of human embryonic stem cells to definitive endoderm

Nature Biotechnology, 2005
K. D’Amour   +5 more
exaly   +2 more sources

Vertebrate Endoderm Development

Annual Review of Cell and Developmental Biology, 1999
▪ Abstract  Endoderm, one of the three principal germ layers, contributes to all organs of the alimentary tract. For simplicity, this review divides formation of endodermal organs into four fundamental steps: (a) formation of endoderm during gastrulation, (b) morphogenesis of a gut tube from a sheet of cells, (c) budding of organ domains from the tube,
J M, Wells, D A, Melton
openaire   +2 more sources

The Endoderm

2023
This chapter discusses the Sox17 transcription factor, which is crucial for the specification of the endoderm that constructs the digestive (gut) tube and the respiratory tube. It analyzes the endoderm in the posterior which becomes a collection of midgut-hindgut precursor cells forming the intestines and the endoderm near the head that form the ...
Michael J. F. Barresi, Scott F. Gilbert
openaire   +1 more source

Extraembryonic Endoderm cells as a model of endoderm development

Development, Growth & Differentiation, 2013
In recent years the multipotent extraembryonic endoderm (XEN) stem cells have been the center of much attention. In vivo, XEN cells contribute to the formation of the extraembryonic endoderm, visceral and parietal endoderm and later on, the yolk sac.
Moerkamp, A.T.   +5 more
openaire   +3 more sources

Coordination between endoderm progression and gastruloid elongation controls endodermal morphotype choice

2023
AbstractEmbryos mostly follow a single morphogenetic trajectory, where variability is largely quantitative with no qualitative differences. This robustness stands in contrast to in-vitro embryo-like models, which, like most organoids, display a high degree of variability.
Naama Farag, Chen Schiff, Iftach Nachman
openaire   +1 more source

Vaginal endodermal sinus tumor

The Indian Journal of Pediatrics, 2005
Malignant germ cell tumors are rare tumors of childhood accounting less than 3% of pediatric malignancies, and endodermal sinus tumor (EST) is the most common histological subtype. The vagina is an extremely rare site for germ cell tumors (GCT). A one-year female was admitted with history of bleeding per vagina.
Vijay, Kumar   +3 more
openaire   +2 more sources

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