Results 1 to 10 of about 604,863 (290)

Nomenclature for endogenous retrovirus (ERV) loci [PDF]

Retrovirology, 2018
Retroviral integration into germline DNA can result in the formation of a vertically inherited proviral sequence called an endogenous retrovirus (ERV).
Robert J. Gifford, Jonas Blomberg, John M. Coffin, Hung Fan, Thierry Heidmann, Jens Mayer, Jonathan Stoye, Michael Tristem, Welkin E. Johnson   +8 more
doaj   +7 more sources

The increased expression levels of human endogenous retrovirus-K envelope and human endogenous retrovirus-H polymerase transcripts in laryngeal squamous cell carcinoma [PDF]

Virology Journal
Laryngeal squamous cell carcinoma (LSCC) is a significant subtype of head and neck cancers, with tobacco and alcohol being primary risk factors. Many studies have shown that human endogenous retroviruses (HERVs), specifically HERV-K and HERV-H, have been
Mehrnaz Kaffashian, Amin Tadayoni Nia, Ehsan Khadivi, Mohammad Farahmand, Zabihollah Shoja, Saeid Amel Jamehdar, Somayeh Jalilvand   +6 more
doaj   +4 more sources

Endogenous Retrovirus 3 – History, Physiology, and Pathology [PDF]

Frontiers in Microbiology, 2018
Endogenous viral elements (EVE) seem to be present in all eukaryotic genomes. The composition of EVE varies between different species. The endogenous retrovirus 3 (ERV3) is one of these elements that is present only in humans and other Catarrhini ...
Yomara Y. Bustamante Rivera, Christine Brütting, Christine Brütting, Caroline Schmidt, Ines Volkmer, Martin S. Staege   +5 more
doaj   +4 more sources

Endogenous retrovirus-encoded Syncytin-2 contributes to exosome-mediated immunosuppression of T cells† [PDF]

Biology of Reproduction, 2019
Modulation of the activation status of immune cell populations during pregnancy depends on placental villous cytotrophoblast (VCT) cells and the syncytiotrophoblast (STB).
Adjimon Gatien Lokossou, Caroline Toudic, Phuong Nguyen, Xavier Elisseeff, Amandine Vargas, Éric Rassart, Julie Lafond, Line Leduc, Steve Bourgault, Caroline Gilbert, Tatiana Scorza, Jorge M. Tolosa, Benoı̂t Barbeau   +12 more
openalex   +2 more sources

Human Endogenous Retrovirus K (HML-2) in Health and Disease

Frontiers in Microbiology, 2020
Human endogenous retroviruses (HERVs) are derived from exogenous retrovirus infections in the evolution of primates and account for about 8% of the human genome.
Bei Xue, Bei Xue, Leonardo A. Sechi, Leonardo A. Sechi, David J. Kelvin, David J. Kelvin, David J. Kelvin   +6 more
doaj   +2 more sources

In-depth analysis of endogenous retrovirus expression in glioblastoma [PDF]

Mobile DNA
Background Human endogenous retroviruses (HERVs) are remnants of ancient viral infections and comprise 6–8% of the human genome. Their biological functions in cancer remain poorly understood, especially in glioblastoma, the most common and deadly primary
Daniel A. Murimi-Worstell, Irene B. Murimi-Worstell, Farrah M. Roy, Aidan Burn, Michael Freeman, Ralph B. Puchalski, John M. Coffin   +6 more
doaj   +2 more sources

Co-option of an endogenous retrovirus envelope for host defense in hominid ancestors

eLife, 2017
Endogenous retroviral sequences provide a molecular fossil record of ancient infections whose analysis might illuminate mechanisms of viral extinction.
Daniel Blanco-Melo, Robert J Gifford, Paul D Bieniasz   +2 more
doaj   +2 more sources

Functional cis-regulatory modules encoded by mouse-specific endogenous retrovirus

Nature Communications, 2017
The gene-battery model posits transposable elements (TEs) may becis-regulatory elements to control gene expression. Here, mouse-specific TEs are shown as binding sites for multiple collaborating transcription factors in embryonic stem cells, and act as ...
Vasavi Sundaram, Mayank N. K. Choudhary, Erica Pehrsson, Xiaoyun Xing, Christopher Fiore, Manishi Pandey, Brett Maricque, Methma Udawatta, Duc Ngo, Yujie Chen, Asia Paguntalan, Tammy Ray, Ava Hughes, Barak A. Cohen, Ting Wang   +14 more
doaj   +2 more sources

Molecular architecture and conservation of an immature human endogenous retrovirus

Nature Communications, 2023
The human endogenous retrovirus K (HERV-K) is the most recently acquired endogenous retrovirus in the human genome and is activated and expressed in many cancers and amyotrophic lateral sclerosis.
Anna-Sophia Krebs, Hsuan-Fu Liu, Ye Zhou, Juan S. Rey, Lev Levintov, Juan Shen, Andrew Howe, Juan R. Perilla, Alberto Bartesaghi, Peijun Zhang   +9 more
doaj   +2 more sources

Human endogenous retrovirus K contributes to a stem cell niche in glioblastoma

Journal of Clinical Investigation, 2023
Human endogenous retroviruses (HERVs) are ancestral viral relics that constitute nearly 8% of the human genome. Although normally silenced, the most recently integrated provirus HERV-K (HML-2) can be reactivated in certain cancers.
Ashish H. Shah, Sarah R. Rivas, Tara T. Doucet-O’Hare, Vaidya Govindarajan, Catherine Demarino, Tongguang Wang, L. Ampie, Yong Zhang, Y. Banasavadi-Siddegowda, S. Walbridge, D. Maric, M. Garcia-Montojo, Robert K Suter, Myoung-Hwa Lee, K. Zaghloul, J. Steiner, A. Elkahloun, Jay Chandar, D. Seetharam, Jelisah F. Desgraves, Wenxue Li, Kory R. Johnson, Michael E. Ivan, R. Komotar, Mark R. Gilbert, John D Heiss, A. Nath   +26 more
semanticscholar   +1 more source