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Molecular architecture and conservation of an immature human endogenous retrovirus [PDF]

open access: yesNature Communications, 2023
The human endogenous retrovirus K (HERV-K) is the most recently acquired endogenous retrovirus in the human genome and is activated and expressed in many cancers and amyotrophic lateral sclerosis.
Anna-Sophia Krebs   +9 more
doaj   +6 more sources

Further varieties of ancient endogenous retrovirus in human DNA [PDF]

open access: yesMobile DNA
A retrovirus inserts its genome into the DNA of a cell, occasionally a germ-line cell that gives rise to descendants of the host organism: it is then called an endogenous retrovirus (ERV).
Martin C. Frith
doaj   +2 more sources

Overexpression of Endogenous Retroviruses and Malignancy Markers in Neuroblastoma Cell Lines by Medium-Induced Microenvironmental Changes

open access: yesFrontiers in Oncology, 2021
Neuroblastoma (NB) is the commonest solid tumor outside the central nervous system in infancy and childhood with a unique biological heterogeneity. In patients with advanced, metastasizing neuroblastoma, treatment failure and poor prognosis is often ...
Lisa Wieland   +8 more
doaj   +1 more source

Are dogs not susceptible to retroviral infections?

open access: yesAnimal Diseases, 2023
Retroviruses have been proven to cause infections and diseases in a series of mammalian hosts but not in dogs. Then, this letter discussed the dog susceptibility to retrovirus infection, encompassing arguments to understand why dogs may have not been ...
Jorge Casseb   +2 more
doaj   +1 more source

The restriction of zoonotic PERV transmission by human APOBEC3G. [PDF]

open access: yesPLoS ONE, 2007
The human APOBEC3G protein is an innate anti-viral factor that can dominantly inhibit the replication of some endogenous and exogenous retroviruses. The prospects of purposefully harnessing such an anti-viral defense are under investigation.
Stefán R Jónsson   +5 more
doaj   +1 more source

The Kidney-Associated Microbiome of Wild-Caught Artibeus spp. in Grenada, West Indies

open access: yesAnimals, 2021
Bats are capable of asymptomatically carrying a diverse number of microorganisms, including human pathogens, due to their unique immune system. Because of the close contact between bats and humans, there is a possibility for interspecies transmission and
Maria E. Ramos-Nino   +5 more
doaj   +1 more source

Structure of the Core Postfusion Porcine Endogenous Retrovirus Fusion Protein

open access: yesmBio, 2022
Retroviral elements from endogenous retroviruses have functions in mammalian physiology. The best-known examples are the envelope proteins that function in placenta development and immune suppression.
Trevor T. Dean   +2 more
doaj   +1 more source

An endogenous lentivirus in the germline of a rodent

open access: yesRetrovirology, 2022
Lentiviruses (genus Lentivirus) are complex retroviruses that infect a broad range of mammals, including humans. Unlike many other retrovirus genera, lentiviruses have only rarely been incorporated into the mammalian germline.
Roziah Kambol   +2 more
doaj   +1 more source

Differential Expression of HERV-W in Peripheral Blood in Multiple Sclerosis and Healthy Patients in Two Different Ethnic Groups

open access: yesFrontiers in Pharmacology, 2020
Overexpression of the Human endogenous retrovirus W (HERV-W) group of inherited retroviruses has been consistently linked with Multiple Sclerosis (MS). However most of the studies on this link have focused on European genetic groups with a very high risk
Rachael Tarlinton   +8 more
doaj   +1 more source

Vaccination against the Koala Retrovirus (KoRV): Problems and Strategies

open access: yesAnimals, 2021
The koala retrovirus (KoRV) is spreading in the koala population from the north to the south of Australia and is also in the process of endogenization into the koala genome.
Joachim Denner
doaj   +1 more source

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