Results 11 to 20 of about 71,944 (228)
Endogenous retrovirus envelope as a tumor-associated immunotherapeutic target in murine osteosarcoma
iScience, 2021 Summary: Osteosarcoma remains one of the deadliest cancers in pediatrics and young adults. We administered two types of immunotherapies, oncolytic virotherapy and immune checkpoint inhibition, to two murine osteosarcoma models and observed divergent ...
Mary Frances Wedekind +15 more
doaj +1 more source
Are dogs not susceptible to retroviral infections?
Animal Diseases, 2023 Retroviruses have been proven to cause infections and diseases in a series of mammalian hosts but not in dogs. Then, this letter discussed the dog susceptibility to retrovirus infection, encompassing arguments to understand why dogs may have not been ...
Jorge Casseb +2 more
doaj +1 more source
The restriction of zoonotic PERV transmission by human APOBEC3G. [PDF]
PLoS ONE, 2007 The human APOBEC3G protein is an innate anti-viral factor that can dominantly inhibit the replication of some endogenous and exogenous retroviruses. The prospects of purposefully harnessing such an anti-viral defense are under investigation.
Stefán R Jónsson +5 more
doaj +1 more source
Differential Regulation of Growth-Promoting Signalling Pathways by E-Cadherin [PDF]
, 2010 Background: Despite the well-documented association between loss of E-cadherin and carcinogenesis, as well as the link between restoration of its expression and suppression of proliferation in carcinoma cells, the ability of E-cadherin to modulate growth-
Dawn C. Walker +4 more
core +11 more sources
The Kidney-Associated Microbiome of Wild-Caught Artibeus spp. in Grenada, West Indies
Animals, 2021 Bats are capable of asymptomatically carrying a diverse number of microorganisms, including human pathogens, due to their unique immune system. Because of the close contact between bats and humans, there is a possibility for interspecies transmission and
Maria E. Ramos-Nino +5 more
doaj +1 more source
An endogenous lentivirus in the germline of a rodent
Retrovirology, 2022 Lentiviruses (genus Lentivirus) are complex retroviruses that infect a broad range of mammals, including humans. Unlike many other retrovirus genera, lentiviruses have only rarely been incorporated into the mammalian germline.
Roziah Kambol +2 more
doaj +1 more source
Structure of the Core Postfusion Porcine Endogenous Retrovirus Fusion Protein
mBio, 2022 Retroviral elements from endogenous retroviruses have functions in mammalian physiology. The best-known examples are the envelope proteins that function in placenta development and immune suppression.
Trevor T. Dean +2 more
doaj +1 more source
Frontiers in Pharmacology, 2020 Overexpression of the Human endogenous retrovirus W (HERV-W) group of inherited retroviruses has been consistently linked with Multiple Sclerosis (MS). However most of the studies on this link have focused on European genetic groups with a very high risk
Rachael Tarlinton +8 more
doaj +1 more source
Vaccination against the Koala Retrovirus (KoRV): Problems and Strategies
Animals, 2021 The koala retrovirus (KoRV) is spreading in the koala population from the north to the south of Australia and is also in the process of endogenization into the koala genome.
Joachim Denner
doaj +1 more source
Larger mammalian body size leads to lower retroviral activity [PDF]
, 2014 Retroviruses have been infecting mammals for at least 100 million years, leaving descendants in host genomes known as endogenous retroviruses (ERVs). The abundance of ERVs is partly determined by their mode of replication, but it has also been suggested ...
Belshaw, Robert +5 more
core +3 more sources