Results 31 to 40 of about 71,944 (228)

Assessment of porcine endogenous retrovirus transmission across an alginate barrier used for the encapsulation of porcine islets [PDF]

, 2018
BACKGROUND: Subcutaneous implantation of a macroencapsulated patch containing human allogenic islets has been successfully used to alleviate type 1 diabetes mellitus (T1DM) in a human recipient without the need for immunosuppression.
Crossan, Claire, Gianello, Pierre, Mourad, Nizar I., Scobie, Linda, Smith, Karen   +4 more
core   +1 more source

Origin and recent expansion of an endogenous gammaretroviral lineage in domestic and wild canids

Retrovirology, 2019
Background Vertebrate genomes contain a record of retroviruses that invaded the germlines of ancestral hosts and are passed to offspring as endogenous retroviruses (ERVs).
Julia V. Halo, Amanda L. Pendleton, Abigail S. Jarosz, Robert J. Gifford, Malika L. Day, Jeffrey M. Kidd   +5 more
doaj   +1 more source

Spatiotemporal variations in retrovirus-host interactions among Darwin’s finches

Nature Communications, 2022
Endogenous retroviruses (ERV) are inherited remains of retroviruses that have colonized host genomes during evolution. Here the authors observe considerable species-specific ERV variation among Darwin’s finches, reflecting historic retrovirus-host ...
Jason Hill, Mette Lillie, Mats E. Pettersson, Carl-Johan Rubin, B. Rosemary Grant, Peter R. Grant, Leif Andersson, Patric Jern   +7 more
doaj   +1 more source

Human endogenous retrovirus-H insertion screening

Molecular Medicine Reports, 2013
Endogenous retroviruses (ERVs) and ERV-like sequences comprise 8% of the human genome. We aimed to analyze genome integration polymorphisms of human endogenous retrovirus (HERV)-H by the inter-retrotransposon amplified polymorphism (IRAP) technique using the sequences of LTR7A (450 bp), LTR7B (445 bp) and LTR7C (471 bp).
Guliyev, Mehrab, YILMAZ, Sibel, Sahin, Kaniye, Gozukirmizi, Nermin, Marakli, Sevgi   +4 more
openaire   +4 more sources

Loss of histone reader Phf7 leads to immune pathways activation via endogenous retroviruses during spermiogenesis

iScience, 2023
Summary: Genetic studies have elucidated the critical roles of Phf7 in germline development in animals; however, the exact etiology of Phf7 mutations leading to male infertility and the possibility of mechanism-based therapy are still unclear and warrant
Jianxing Cheng, Tongtong Li, Zhongjie Zheng, Xueguang Zhang, Mengyang Cao, Wenhao Tang, Kai Hong, Rui Zheng, Jichun Shao, Xiaomiao Zhao, Hui Jiang, Wenming Xu, Haocheng Lin   +12 more
doaj   +1 more source

FOXP3 interacts with hnRNPF to modulate pre-mRNA alternative splicing [PDF]

, 2018
FOXP3 promotes the development and function of regulatory T cells mainly through regulating the transcription of target genes. RNA alternative splicing has been implicated in a wide range of physiological and pathophysiological processes.
Du, Jianguang, Wang, Qun, Zhou, Baohua, Ziegler, Steven F.   +3 more
core   +1 more source

Identification of receptors for pig endogenous retrovirus [PDF]

Proceedings of the National Academy of Sciences, 2003
Xenotransplantation of porcine tissues has the potential to treat a wide variety of major health problems including organ failure and diabetes. Balanced against the potential benefits of xenotransplantation, however, is the risk of human infection with a porcine microorganism.
Thomas A, Ericsson, Yasuhiro, Takeuchi, Christian, Templin, Gary, Quinn, Shelli F, Farhadian, James C, Wood, Beth A, Oldmixon, Kristen M, Suling, Jennifer K, Ishii, Yoshinori, Kitagawa, Takayuki, Miyazawa, Daniel R, Salomon, Robin A, Weiss, Clive, Patience   +13 more
openaire   +2 more sources

Deltaretroviruses have circulated since at least the Paleogene and infected a broad range of mammalian species

Retrovirology, 2019
The Deltaretrovirus genus of retroviruses (family Retroviridae) includes the human T cell leukemia viruses and bovine leukemia virus (BLV). Relatively little is known about the biology and evolution of these viruses, because only a few species have been ...
Tomáš Hron, Daniel Elleder, Robert J. Gifford   +2 more
doaj   +1 more source

Rationale and Methodology of Reprogramming for Generation of Induced Pluripotent Stem Cells and Induced Neural Progenitor Cells. [PDF]

, 2016
Great progress has been made regarding the capabilities to modify somatic cell fate ever since the technology for generation of induced pluripotent stem cells (iPSCs) was discovered in 2006.
Biswas, Sangita, Deng, Wenbin, Guo, Fuzheng, Tian, Zuojun   +3 more
core   +2 more sources

Ancestry of a human endogenous retrovirus family [PDF]

Journal of Virology, 1989
The human endogenous retrovirus type II (HERVII) family of HERV genomes has been found by Southern blot analysis to be characteristic of humans, apes, and Old World monkeys. New World monkeys and prosimians lack HERVII proviral genomes. Cellular DNAs of humans, common chimpanzees, gorillas, and orangutans, but not lesser ape lar gibbons, appear to ...
MARIANI COSTANTINI, Renato, Horn TM, Callahan R.   +2 more
openaire   +3 more sources