Distribution, diversity and evolution of endogenous retroviruses in perissodactyl genomes [PDF]
, 2018 The evolution of mammalian genomes has been shaped by interactions with endogenous retroviruses (ERVs). In this study, we investigated the distribution and diversity of ERVs in the mammalian order Perissodactyla, with a view to understanding their impact
Gifford, Robert +2 more
core +1 more source
Transspecies Transmission of the Endogenous Koala Retrovirus [PDF]
Journal of Virology, 2006 ABSTRACTThe koala retrovirus (KoRV) is a gammaretrovirus closely related to the gibbon ape leukemia virus and induces leukemias and immune deficiencies associated with opportunistic infections, such as chlamydiosis. Here we characterize a KoRV newly isolated from an animal in a German zoo and show infection of human and rat cell lines in vitro and of ...
Uwe, Fiebig +4 more
openaire +2 more sources
Regression/eradication of gliomas in mice by a systemically-deliverable ATF5 dominant-negative peptide. [PDF]
, 2016 Malignant gliomas have poor prognosis and urgently require new therapies. Activating Transcription Factor 5 (ATF5) is highly expressed in gliomas, and interference with its expression/function precipitates targeted glioma cell apoptosis in vitro and in ...
Angelastro, James +11 more
core +5 more sources
Genomic analysis of endogenous retrovirus elements in chinese flocks of economic importance [PDF]
Kafkas Universitesi Veteriner Fakültesi Dergisi, 2017 Since the status of endogenous retrovirus elements in Chinese chickens is currently unknown, the embryonated eggs were analyzed from 10 different chicken breeds throughout China. In this study, endogenous retrovirus elements were analyzed including: EAV,
GU YF +4 more
doaj +1 more source
Characterization of porcine endogenous retrovirus expression in neonatal and adult pig pancreatic islets [PDF]
, 2017 BACKGROUND: Pig islets represent an alternative to the current modes of treatment for patients with diabetes. However, the concerns over pathogen transmission including that of PERV limit their immediate, widespread usage in humans.
Akiyoshi +36 more
core +1 more source
Novel Endogenous Retrovirus in Rabbits Previously Reported as Human Retrovirus 5 [PDF]
Journal of Virology, 2002 ABSTRACT Human retrovirus 5 (HRV-5) represented a fragment of a novel retrovirus sequence identified in human RNA and DNA preparations. In this study, the genome of HRV-5 was cloned and sequenced and integration sites were analyzed. Using PCR and Southern hybridization, we showed that HRV-5 is not integrated into human DNA.
David J, Griffiths +3 more
openaire +2 more sources
Evaluation of cynomolgus macaque (Macaca fascicularis) endogenous retrovirus expression following simian immunodeficiency virus infection. [PDF]
PLoS ONE, 2012 Human endogenous retrovirus type K (HERV-K) transcripts are upregulated in the plasma of HIV-infected individuals and have been considered as targets for an HIV vaccine.
Angie K Marsh +5 more
doaj +1 more source
Complete genome sequences of two feline Leukemia virus subgroup B isolates with novel recombination sites [PDF]
, 2013 It is generally accepted that all primary isolates of feline leukemia virus (FeLV) contain a subgroup A virus (FeLV-A) that is essential for transmission.
Bae +12 more
core +1 more source
Endogenous retrovirus-mediated genomic variations in chimpanzees [PDF]
Mobile Genetic Elements, 2014 Transposable elements (TEs) have played a significant role in the evolution of host genome by triggering genomic rearrangements. TEs have been studied in various research fields, ranging from population genomics to personalized medicines. Human-specific TEs and TEs existing in the human genome have been well studied.
Yun-Ji, Kim, Kyudong, Han
openaire +2 more sources
Genetic Diversity of Koala Retroviral Envelopes
Viruses, 2015 Genetic diversity, attributable to the low fidelity of reverse transcription, recombination and mutation, is an important feature of infectious retroviruses.
Wenqin Xu +4 more
doaj +1 more source