Results 111 to 120 of about 36,840 (231)

Osteoarthritis: Mechanisms and Therapeutic Advances

open access: yesMedComm, Volume 6, Issue 8, August 2025.
A schematic illustration of the pathogenesis and emerging therapeutic strategies for OA, including: risk factors and molecular mechanisms of OA, joint changes between healthy and OA conditions, and current emerging therapeutic approaches for OA. Abbreviations: IA: intra‐articular injection; EVs: extracellular vesicles. ABSTRACT Osteoarthritis (OA) is a
Wei Liu   +3 more
wiley   +1 more source

Age and Sex Effects on Blood Retrotransposable Element Expression Levels: Findings From the Population‐Based Rhineland Study

open access: yesAging Cell, Volume 24, Issue 8, August 2025.
Retrotransposable element (RTE) expression increases with chronological and biological age and is negatively associated with heterochromatin regulators. Moreover, RTE expression shows sex‐specific differences, with higher levels in men and enrichment for immune‐related pathways.
Valentina Talevi   +6 more
wiley   +1 more source

Genomic imprinting at a porcine ZNF locus via a canonical imprinting mechanism

open access: yesAnimal Genetics, Volume 56, Issue 4, August 2025.
Abstract Genomic imprinting causes parent‐of‐origin dependent gene expression, primarily driven by a subset of germline differentially methylated regions that function as imprinting control regions at promoter‐associated CpG islands. While these mechanisms have been investigated in depth in mice and humans, our understanding of the molecular basis of ...
Jinsoo Ahn   +5 more
wiley   +1 more source

Causes of mortality in koalas autopsied at the University of Melbourne

open access: yesAustralian Veterinary Journal, Volume 103, Issue 8, Page 500-505, August 2025.
Objective To determine the causes of mortality in koalas autopsied at the University of Melbourne based on the retrospective analysis of autopsy reports. Methods The autopsy reports of 239 koalas examined at the University of Melbourne from 1970 to 2023 were reviewed to determine which of the comorbidities present was the primary cause to which death ...
L Wilson   +8 more
wiley   +1 more source

Advances in the Study of Pluripotent Stem Cells in Livestock

open access: yesCell Proliferation, Volume 58, Issue 8, August 2025.
Livestock pluripotent stem cells include embryonic stem cells (ESCs) isolated from the inner cell mass of blastocysts and induced pluripotent stem cells (iPSCs) derived from somatic cell reprogramming. They hold significant potential for applications in livestock breed improvement, rapid propagation, human disease modelling and human organ ...
Xinyi Zhou   +6 more
wiley   +1 more source

HOST RANGE AND INTERFERENCE STUDIES OF THREE CLASSES OF PIG ENDOGENOUS RETROVIRUS [PDF]

open access: green, 1999
Yasuhiro Takeuchi   +6 more
openalex   +1 more source

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