Remnants of an Ancient Deltaretrovirus in the Genomes of Horseshoe Bats (Rhinolophidae) [PDF]
Viruses, 2018 Endogenous retrovirus (ERV) sequences provide a rich source of information about the long-term interactions between retroviruses and their hosts. However, most ERVs are derived from a subset of retrovirus groups, while ERVs derived from certain other ...
Tomáš Hron +7 more
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Nomenclature for endogenous retrovirus (ERV) loci [PDF]
Retrovirology, 2018 Retroviral integration into germline DNA can result in the formation of a vertically inherited proviral sequence called an endogenous retrovirus (ERV).
Robert J. Gifford +8 more
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Endogenous Retrovirus 3 – History, Physiology, and Pathology [PDF]
Frontiers in Microbiology, 2018 Endogenous viral elements (EVE) seem to be present in all eukaryotic genomes. The composition of EVE varies between different species. The endogenous retrovirus 3 (ERV3) is one of these elements that is present only in humans and other Catarrhini ...
Yomara Y. Bustamante Rivera +5 more
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The increased expression levels of human endogenous retrovirus-K envelope and human endogenous retrovirus-H polymerase transcripts in laryngeal squamous cell carcinoma [PDF]
Virology JournalLaryngeal squamous cell carcinoma (LSCC) is a significant subtype of head and neck cancers, with tobacco and alcohol being primary risk factors. Many studies have shown that human endogenous retroviruses (HERVs), specifically HERV-K and HERV-H, have been
Mehrnaz Kaffashian +6 more
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In-depth analysis of endogenous retrovirus expression in glioblastoma [PDF]
Mobile DNABackground Human endogenous retroviruses (HERVs) are remnants of ancient viral infections and comprise 6–8% of the human genome. Their biological functions in cancer remain poorly understood, especially in glioblastoma, the most common and deadly primary
Daniel A. Murimi-Worstell +6 more
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Reconstitution of an infectious human endogenous retrovirus.
PLoS Pathogens, 2007 The human genome represents a fossil record of ancient retroviruses that once replicated in the ancestors of contemporary humans. Indeed, approximately 8% of human DNA is composed of sequences that are recognizably retroviral.
Young Nam Lee, Paul D Bieniasz
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Co-option of an endogenous retrovirus envelope for host defense in hominid ancestors [PDF]
eLife, 2017 Endogenous retroviral sequences provide a molecular fossil record of ancient infections whose analysis might illuminate mechanisms of viral extinction.
Daniel Blanco-Melo +2 more
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Endogenization of a Prosimian Retrovirus during Lemur Evolution [PDF]
Viruses, 2021 Studies of viruses that coevolved with lemurs provide an opportunity to understand the basal traits of primate viruses and provide an evolutionary context for host-virus interactions.
Kathleen Apakupakul +5 more
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Molecular architecture and conservation of an immature human endogenous retrovirus
Nature Communications, 2023 The human endogenous retrovirus K (HERV-K) is the most recently acquired endogenous retrovirus in the human genome and is activated and expressed in many cancers and amyotrophic lateral sclerosis.
Anna-Sophia Krebs +9 more
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Larger mammalian body size leads to lower retroviral activity [PDF]
, 2014 Retroviruses have been infecting mammals for at least 100 million years, leaving descendants in host genomes known as endogenous retroviruses (ERVs). The abundance of ERVs is partly determined by their mode of replication, but it has also been suggested ...
Belshaw, Robert +5 more
core +21 more sources