Mechanisms of Late Restriction Induced by an Endogenous Retrovirus [PDF]
ABSTRACT The host has developed during evolution a variety of “restriction factors” to fight retroviral infections. We investigated the mechanisms of a unique viral block acting at late stages of the retrovirus replication cycle. The sheep genome is colonized by several copies of endogenous retroviruses, known as enJSRVs, which are highly ...
Arnaud, Frederick+2 more
openaire +4 more sources
Evaluation of cynomolgus macaque (Macaca fascicularis) endogenous retrovirus expression following simian immunodeficiency virus infection. [PDF]
Human endogenous retrovirus type K (HERV-K) transcripts are upregulated in the plasma of HIV-infected individuals and have been considered as targets for an HIV vaccine.
Angie K Marsh+5 more
doaj +1 more source
Genetic Diversity of Koala Retroviral Envelopes
Genetic diversity, attributable to the low fidelity of reverse transcription, recombination and mutation, is an important feature of infectious retroviruses.
Wenqin Xu+4 more
doaj +1 more source
Remnants of an Ancient Deltaretrovirus in the Genomes of Horseshoe Bats (Rhinolophidae)
Endogenous retrovirus (ERV) sequences provide a rich source of information about the long-term interactions between retroviruses and their hosts. However, most ERVs are derived from a subset of retrovirus groups, while ERVs derived from certain other ...
Tomáš Hron+7 more
doaj +1 more source
Endogenous retrovirus envelope as a tumor-associated immunotherapeutic target in murine osteosarcoma
Summary: Osteosarcoma remains one of the deadliest cancers in pediatrics and young adults. We administered two types of immunotherapies, oncolytic virotherapy and immune checkpoint inhibition, to two murine osteosarcoma models and observed divergent ...
Mary Frances Wedekind+15 more
doaj
Origin and recent expansion of an endogenous gammaretroviral lineage in domestic and wild canids
Background Vertebrate genomes contain a record of retroviruses that invaded the germlines of ancestral hosts and are passed to offspring as endogenous retroviruses (ERVs).
Julia V. Halo+5 more
doaj +1 more source
Spatiotemporal variations in retrovirus-host interactions among Darwin’s finches
Endogenous retroviruses (ERV) are inherited remains of retroviruses that have colonized host genomes during evolution. Here the authors observe considerable species-specific ERV variation among Darwin’s finches, reflecting historic retrovirus-host ...
Jason Hill+7 more
doaj +1 more source
Evolution and subfamilies of HERVL human endogenous retrovirus. [PDF]
Abstract Background Endogenous retroviruses (ERVs), which blur the boundary between virus and transposable element, are genetic material derived from retroviruses and have important implications for evolution.
Zhang H, Frith MC.
europepmc +3 more sources
The envelope of human endogenous retrovirus in neuro-inflammation [PDF]
retroviruses, retroelements and their hosts Meet ing abstracts - A single PDF containing all abstracts in this Supplement is available here . http://www.
Marche Patrice N+7 more
doaj +3 more sources
The Deltaretrovirus genus of retroviruses (family Retroviridae) includes the human T cell leukemia viruses and bovine leukemia virus (BLV). Relatively little is known about the biology and evolution of these viruses, because only a few species have been ...
Tomáš Hron+2 more
doaj +1 more source