Results 91 to 100 of about 13,041 (209)

Diagnostic and Therapeutic Roles of Extracellular Vesicles in Chronic Kidney Disease: A Systematic Review

open access: yesJournal of Extracellular Vesicles, Volume 15, Issue 5, May 2026.
This systematic review compiles and analyses 364 studies on chronic kidney disease (CKD) that investigated extracellular vesicles (EVs) for diagnostic and therapeutic applications. By systematically categorizing data according to EV source and cargo, it provides an integrated overview of EV application for CKD, highlighting common approaches and shared
Tunahan Ergunay   +2 more
wiley   +1 more source

The role of endoglin in post-ischemic revascularization [PDF]

open access: yesAngiogenesis, 2016
Following arterial occlusion, blood vessels respond by forming a new network of functional capillaries (angiogenesis), by reorganizing preexisting capillaries through the recruitment of smooth muscle cells to generate new arteries (arteriogenesis) and by growing and remodeling preexisting collateral arterioles into physiologically relevant arteries ...
Núñez-Gómez, E.   +4 more
openaire   +3 more sources

Autologous correction in patient induced pluripotent stem cell-endothelial cells to identify a novel pathogenic mutation of hereditary hemorrhagic telangiectasia

open access: yesPulmonary Circulation, 2020
Hereditary hemorrhagic telangiectasia is a rare disease with autosomal dominant inheritance. More than 80% hereditary hemorrhagic telangiectasia patients carry heterozygous mutations of Endoglin or Activin receptor-like kinase-1 genes.
Fang Zhou   +6 more
doaj   +1 more source

Self‐Feeding of Engineered Tissues via Controlled Glucose Release Facilitates Survival and Vascularization of Living Implants

open access: yesAdvanced Functional Materials, Volume 36, Issue 32, 20 April 2026.
ABSTRACT Engineering living matter has great clinical potential to deliver functional replacement organs. However, clinical translation remains hampered by the current inability to maintain viability of clinically relevant‐sized constructs. During the pre‐vascular phase, implants rely on nutrient diffusion for survival, which is insufficient at ...
Melvin Gurian   +5 more
wiley   +1 more source

Endoglin regulates renal ischaemia-reperfusion injury

open access: yes, 2006
14 páginas, 10 figuras -- PAGS nros. 2106-2119Background. Renal ischaemia–reperfusion (I–R) can cause acute tubular necrosis and chronic renal deterioration.
Pérez-Barriocanal, Fernando   +7 more
core   +1 more source

Association of Alk1 and Endoglin Polymorphisms with Cardiovascular Damage

open access: yesScientific Reports, 2020
Cardiovascular diseases are associated to risk factors as obesity, hypertension and diabetes. The transforming growth factor-β1 receptors ALK1 and endoglin regulate blood pressure and vascular homeostasis.
Mercedes Garzon-Martinez   +6 more
doaj   +1 more source

Strawberry Notch 1 Acts as a Transcriptional Regulator Driving Oncogenic Programs in Liver Carcinogenesis

open access: yesAdvanced Science, Volume 13, Issue 20, 9 April 2026.
This study reports that SBNO1 protein is upregulated in several cancer entities. SBNO1 protein interacts with the basal transcription factor TFIID via TAF4, enabling its recruitment to transcription start sites and the modulation of target gene expression.
Sarah Fritzsche   +21 more
wiley   +1 more source

Transgenic mice expressing human L-endoglin.

open access: yes, 2014
(a) Schematic representation of the DNA construct used to generate transgenic mice expressing human L-endoglin. A 5.2-kb SalI/KpnI fragment, containing a CMV enhancer, an actin enhancer/promoter, a β-globin (BG) intron (fragment SalI/EcoRI), the endoglin
Bárbara Oujo (644102)   +11 more
core   +1 more source

Serum endoglin as a marker in hepatocellular carcinoma

open access: yesThe Egyptian Journal of Internal Medicine, 2015
Introduction Hepatitis C viral (HCV) infection is a major risk factor for liver cirrhosis, liver failure, and hepatocellular carcinoma (HCC). A number of laboratory-based methods has been developed for the noninvasive diagnostic evaluation of HCC ...
Rehab A Mohamed   +5 more
doaj   +1 more source

Rapid endoglin determination in serum samples using an amperometric magneto-actuated disposable immunosensing platform

open access: yes, 2016
A sensitive and rapid method for the determination of the clinically relevant biomarker human endoglin (CD105) in serum samples is presented, involving a magneto-actuated immunoassay and amperometric detection at disposable screen-printed carbon ...
Pingarrón Carrazón, José Manuel   +6 more
core   +1 more source

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