Results 111 to 120 of about 10,232 (247)
PLoS ONECapsular polysaccharides are considered as major virulence factors associated with the ability of multidrug-resistant (MDR) Acinetobacter baumannii to cause severe infections.
Rosesathorn Soontarach +5 more
semanticscholar +1 more source
, 2019 Phage lytic enzymes are enzymes produced by bacterial viruses, either as part of their virion to facilitate bacterial infection through local peptidoglycan degradation, or as soluble proteins to induce massive cell lysis at the end of the lytic ...
Briers, Yves
core +1 more source
MicrobiologyOpen, Volume 14, Issue 6, December 2025.Lactococcus petauri predominated in isolates from outbreaks of lactococcosis, suggesting a shift in disease aetiology. Genomic analysis revealed diverse virulence factors, prophage and resistance genes, while antimicrobial susceptibility testing showed uniform resistance to common antibiotics found in farming systems, emphasising the need for ...
Adam M. Blanchard +9 more
wiley +1 more source
Safety Studies of Pneumococcal Endolysins Cpl-1 and Pal [PDF]
Viruses, 2018 Bacteriophage-derived endolysins have gained increasing attention as potent antimicrobial agents and numerous publications document the in vivo efficacy of these enzymes in various rodent models. However, little has been documented about their safety and toxicity profiles.
Marek Harhala +15 more
openaire +3 more sources
Endolysin NC5 improves early cloxacillin treatment in a mouse model of Streptococcus uberis mastitis
Applied Microbiology and BiotechnologyStreptococcus uberis frequently causes bovine mastitis, an infectious udder disease with significant economic implications for dairy cows. Conventional antibiotics, such as cloxacillin, sometimes have limited success in eliminating S.
Niels Vander Elst +4 more
semanticscholar +1 more source
Genome sequence of Streptococcus mutans bacteriophage M102 [PDF]
, 2017 Bacteriophage M102 is a lytic phage specific for serotype c strains of Streptococcus mutans, a causative agent of dental caries. In this study, the complete genome sequence of M102 was determined.
van der Ploeg, J R.
core
DUF3380 domain from a Salmonella phage endolysin shows potent N -acetylmuramidase activity [PDF]
, 2016 Bacteriophage-encoded endolysins are highly diverse enzymes that cleave the bacterial peptidoglycan layer. Current research focuses on their potential applications in medicine, in food conservation, and as biotechnological tools.
Hans Gerstmans +6 more
core +1 more source
The temperate Burkholderia phage AP3 of the Peduovirinae shows efficient antimicrobial activity against B. cenocepacia of the IIIA lineage [PDF]
, 2016 Burkholderia phage AP3 (vB_BceM_AP3) is a temperate virus of the Myoviridae and the Peduovirinae subfamily (P2likevirus genus). This phage specifically infects multidrug-resistant clinical Burkholderia cenocepacia lineage IIIA strains commonly isolated ...
Briers, Yves +10 more
core +2 more sources
Medicine Bulletin, Volume 1, Issue 2, Page 136-153, December 2025.This review reveals the complex mechanisms by which the brain–gut–liver axis (particularly the gut microbiota and its metabolites) drives MASLD, highlighting the therapeutic value of using phages to target and eliminate pathogenic bacteria and their metabolic products.
Xingtao Zhao +7 more
wiley +1 more source
Bacteriophage φEf11 ORF28 Endolysin, a Multifunctional Lytic Enzyme with Properties Distinct from All Other Identified Enterococcus faecalis Phage Endolysins [PDF]
Applied and Environmental Microbiology, 2019 The emergence of multidrug-resistant pathogenic microorganisms has brought increasing attention to the urgent need for the development of alternative antimicrobial strategies. One such alternative to conventional antibiotics employs lytic enzymes (endolysins) that are produced by bacteriophages in the course of lytic infection.
Hongming Zhang +5 more
openaire +2 more sources