Results 1 to 10 of about 238,870 (356)

DDIAS promotes endometrial cancer progression via β-catenin signaling. [PDF]

open access: yesPLoS ONE
BackgroundDDIAS has been recognized as an oncogene in various cancers, but its role in endometrial cancer remains unexplored.MethodsThe expression of DDIAS in normal endometrium and endometrial cancer samples was analysed via the The Cancer Genome Atlas (
Xiaojuan Tian   +5 more
doaj   +2 more sources

Endometrial cancer [PDF]

open access: yesCanadian Medical Association Journal, 2021
Although endometrial cancer management remains challenging, a deeper understanding of the genetic diversity as well as the drivers of the various pathogenic states of this disease has led to development of divergent management approaches in an effort to improve therapeutic precision in this complex malignancy.
Sobel, Mara   +2 more
  +7 more sources

Expert consensus on genetic counseling in gynecological oncology (2023 edition) [PDF]

open access: yesZhongguo aizheng zazhi, 2023
With the increasing applications of high-throughput genome sequencing technology, there is a growing recognition of the important roles of genetic factors in the occurrence and development of gynecological tumors.

doaj   +1 more source

Endometrial cancer

open access: yesThe Lancet, 2022
Endometrial cancer is the most common gynaecological cancer in high income countries and its incidence is rising globally. Although an ageing population and fewer benign hysterectomies have contributed to this trend, the growing prevalence of obesity is the major underlying cause.
Crosbie, Emma J   +5 more
openaire   +5 more sources

Expression of STAT3 in endometrial carcinoma and its clinicopathological significance [PDF]

open access: yesJichu yixue yu linchuang, 2023
Objective To investigate the expression of signal transducer and activator of transcription 3 (STAT3) in endometrial cancer tissues, and to analyze its relationship with common pathological parameters.
SUN Xinzhao, LUO Yanlu, FAN Jiangtao, ZHONG Xueyan
doaj   +1 more source

Endometrial Cancer [PDF]

open access: yesThe Lancet, 2016
Endometrial cancer is the most common gynecological malignancy in well-developed countries. Biologically and clinicopathologically, endometrial carcinomas are divided into two types: type 1 or estrogen-dependent carcinomas and type 2 or estrogen-independent carcinomas.
Horta, Mariana, Cunha, Teresa Margarida
openaire   +5 more sources

Impact of metabolic syndrome on the risk of endometrial cancer and the role of lifestyle in prevention

open access: yesBiomolecules & Biomedicine, 2022
Endometrial cancer is the second gynecological cancer with the highest global incidence. Among many associated risk factors, metabolic syndrome is an important and preventable one.
Alejandra Rocío Pérez-Martín   +8 more
doaj   +1 more source

Clinical Benefits of Olaparib in Mexican Ovarian Cancer Patients With Founder Mutation BRCA1-Del ex9-12

open access: yesFrontiers in Genetics, 2022
Background: Ovarian cancer (OC) is gynecologic cancer with the highest mortality rate. It is estimated that 13–17% of ovarian cancers are due to heritable mutations in BRCA1 and BRCA2.
Dolores Gallardo-Rincón   +21 more
doaj   +1 more source

Risk of Endometrial Cancer and Frequencies of Invasive Endometrial Procedures in Young Breast Cancer Survivors Treated With Tamoxifen: A Nationwide Study

open access: yesFrontiers in Oncology, 2021
BackgroundAlthough the guidelines recommend gynecological assessment and close monitoring for symptoms of endometrial cancer in postmenopausal breast cancer survivors taking tamoxifen (TAM), the risk of endometrial cancer in young breast cancer survivors
Soojeong Choi   +11 more
doaj   +1 more source

Pathology findings among women with alterations in uterine bleeding patterns in cameroon

open access: yesGynecologic Oncology Reports, 2021
Purpose: Endometrial cancer is on the rise in high-income countries but it has not been adequately studied in low-and-middle income countries especially in sub-Saharan Africa (SSA), likely due to scarce pathology facilities. The purpose of this study was
Simon M. Manga   +11 more
doaj   +1 more source

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