Results 1 to 10 of about 229,435 (354)
Canadian Medical Association Journal, 2021 Although endometrial cancer management remains challenging, a deeper understanding of the genetic diversity as well as the drivers of the various pathogenic states of this disease has led to development of divergent management approaches in an effort to improve therapeutic precision in this complex malignancy.
Sobel, Mara +2 more
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Expert consensus on genetic counseling in gynecological oncology (2023 edition) [PDF]
Zhongguo aizheng zazhi, 2023 With the increasing applications of high-throughput genome sequencing technology, there is a growing recognition of the important roles of genetic factors in the occurrence and development of gynecological tumors.
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Best Practice & Research Clinical Obstetrics & Gynaecology, 2012 Endometrial carcinoma is the most common gynaecological malignancy in the Western world. The standard management of endometrial carcinoma is total hysterectomy and bilateral salpingo-oophorectomy with or without pelvic and para-aortic lymph-node dissection.
Vivek, Arora, Michael A, Quinn
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Expression of STAT3 in endometrial carcinoma and its clinicopathological significance [PDF]
Jichu yixue yu linchuang, 2023 Objective To investigate the expression of signal transducer and activator of transcription 3 (STAT3) in endometrial cancer tissues, and to analyze its relationship with common pathological parameters.
SUN Xinzhao, LUO Yanlu, FAN Jiangtao, ZHONG Xueyan
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The Lancet, 2022 Endometrial cancer is the most common gynaecological cancer in high income countries and its incidence is rising globally. Although an ageing population and fewer benign hysterectomies have contributed to this trend, the growing prevalence of obesity is the major underlying cause.
Crosbie, Emma J +5 more
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The Lancet, 2005 Each year, endometrial cancer develops in about 142,000 women worldwide, and an estimated 42,000 women die from this cancer. The typical age-incidence curve for endometrial cancer shows that most cases are diagnosed after the menopause, with the highest incidence around the seventh decade of life. The appearance of symptoms early in the course explains
Amant, Frédéric +5 more
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Biomolecules & Biomedicine, 2022 Endometrial cancer is the second gynecological cancer with the highest global incidence. Among many associated risk factors, metabolic syndrome is an important and preventable one.
Alejandra Rocío Pérez-Martín +8 more
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Frontiers in Genetics, 2022 Background: Ovarian cancer (OC) is gynecologic cancer with the highest mortality rate. It is estimated that 13–17% of ovarian cancers are due to heritable mutations in BRCA1 and BRCA2.
Dolores Gallardo-Rincón +21 more
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Frontiers in Oncology, 2021 BackgroundAlthough the guidelines recommend gynecological assessment and close monitoring for symptoms of endometrial cancer in postmenopausal breast cancer survivors taking tamoxifen (TAM), the risk of endometrial cancer in young breast cancer survivors
Soojeong Choi +11 more
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npj Precision Oncology, 2023 Endometrial cancer (EC) patients with metastatic/recurrent disease have limited treatment options and poor survival outcomes. Recently, we discovered the FGFR2c splice isoform is associated with poor prognosis in EC patients.
Asmerom T. Sengal +11 more
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