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Canadian Medical Association Journal, 2021 Although endometrial cancer management remains challenging, a deeper understanding of the genetic diversity as well as the drivers of the various pathogenic states of this disease has led to development of divergent management approaches in an effort to improve therapeutic precision in this complex malignancy.
Sobel, Mara +2 more
semanticscholar +9 more sources
The Lancet, 2022 Endometrial cancer is the most common gynaecological cancer in high income countries and its incidence is rising globally. Although an ageing population and fewer benign hysterectomies have contributed to this trend, the growing prevalence of obesity is the major underlying cause.
Crosbie, Emma J +5 more
semanticscholar +6 more sources
DDIAS promotes endometrial cancer progression via β-catenin signaling. [PDF]
PLoS ONEBackgroundDDIAS has been recognized as an oncogene in various cancers, but its role in endometrial cancer remains unexplored.MethodsThe expression of DDIAS in normal endometrium and endometrial cancer samples was analysed via the The Cancer Genome Atlas (
Xiaojuan Tian +5 more
doaj +2 more sources
The role of extracellular vesicles in the communication between endometrial cancer cells and tumour-associated macrophages: a review [PDF]
Journal of Cancer Research and Clinical OncologyEndometrial cancer is a significant threat to the health of women worldwide. Extracellular vesicles are essential for the proliferation, migration, and invasion of cancer cells, whereas tumour-associated macrophages (TAMs) are key regulators of cancer ...
Feng Li, Wei Shi
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Expert consensus on genetic counseling in gynecological oncology (2023 edition) [PDF]
Zhongguo aizheng zazhi, 2023 With the increasing applications of high-throughput genome sequencing technology, there is a growing recognition of the important roles of genetic factors in the occurrence and development of gynecological tumors.
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Best Practice & Research Clinical Obstetrics & Gynaecology, 2012 Endometrial carcinoma is the most common gynaecological malignancy in the Western world. The standard management of endometrial carcinoma is total hysterectomy and bilateral salpingo-oophorectomy with or without pelvic and para-aortic lymph-node dissection.
Vivek, Arora, Michael A, Quinn
+10 more sources
Expression of STAT3 in endometrial carcinoma and its clinicopathological significance [PDF]
Jichu yixue yu linchuang, 2023 Objective To investigate the expression of signal transducer and activator of transcription 3 (STAT3) in endometrial cancer tissues, and to analyze its relationship with common pathological parameters.
SUN Xinzhao, LUO Yanlu, FAN Jiangtao, ZHONG Xueyan
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The Lancet, 2005 Each year, endometrial cancer develops in about 142,000 women worldwide, and an estimated 42,000 women die from this cancer. The typical age-incidence curve for endometrial cancer shows that most cases are diagnosed after the menopause, with the highest incidence around the seventh decade of life. The appearance of symptoms early in the course explains
Amant, Frédéric +5 more
openaire +5 more sources
The Lancet, 2016 Endometrial cancer is the most common gynaecological tumour in developed countries, and its incidence is increasing. The most frequently occurring histological subtype is endometrioid adenocarcinoma. Patients are often diagnosed when the disease is still confined to the uterus.
Morice, P. +4 more
+7 more sources
Biomolecules & Biomedicine, 2022 Endometrial cancer is the second gynecological cancer with the highest global incidence. Among many associated risk factors, metabolic syndrome is an important and preventable one.
Alejandra Rocío Pérez-Martín +8 more
doaj +1 more source