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PDIA6 have been reported to be involved in a variety of cancers, however, the underlying role in endometrial cancer is still unclear. In this study, we aimed to study the function of PDIA6 in endometrial cancer.
Pengling Wang +6 more
doaj +1 more source
In type 1 endometrial cancer, unopposed estrogen stimulation is thought to lead to endometrial hyperplasia which precedes malignant progression. Recent data from our group and others suggest that ALDH activity mediates stemness in endometrial cancer, but
Vei Mah +8 more
doaj +1 more source
Association between diabetes, diabetes treatment and risk of developing endometrial cancer. [PDF]
BackgroundA growing body of evidence suggests that diabetes is a risk factor for endometrial cancer incidence. However, most of these studies used case-control study designs and did not adjust for obesity, an established risk factor for endometrial ...
Beresford, S +8 more
core +2 more sources
Relationship between duration of breast feeding and endometrial cancer: a case-control study [PDF]
Introduction: Endometrial cancer is the most common gynecologic malignancy in developed countries. The incidence of endometrial cancer is increasing in Iran. The risk of endometrial cancer is related to estrogen levels that breastfeeding reduces it. This
Zohreh Yeganeh +5 more
doaj +1 more source
Mutations and amplification of oncogenes in endometrial cancer [PDF]
Alterations in oncogenes are critical steps in the development of endometrial cancer. To investigate the potential clinical relevance of the amplification of the oncogenes c-erbB2, c-myc, and int-2 and the mutation of K-ras in endometrial cancer, 112 ...
An, Han-Xiang +5 more
core +1 more source
Progestins Related to Progesterone and Testosterone Elicit Divergent Human Endometrial Transcriptomes and Biofunctions. [PDF]
Progestins are widely used for the treatment of gynecologic disorders and alone, or combined with an estrogen, are used as contraceptives. While their potencies, efficacies and side effects vary due to differences in structures, doses and routes of ...
Balayan, Shayna +8 more
core +2 more sources
Οutcomes for patients who are diagnosed with breast and endometrial cancer [PDF]
The present study sought to determine the survival outcomes for women diagnosed with breast and endometrial cancer. Using SEER data, a population-based cohort study of women diagnosed with breast and endometrial cancer was conducted.
Margenthaler, Julie A +2 more
core +2 more sources
Total tissue lactate dehydrogenase activity in endometrial carcinoma [PDF]
Lactate dehydrogenase (LDH) is essential for continuous glycolysis necessary for accelerated tumor growth. The aim of this study was to reconsider if assay of total tissue activity of this enzyme could be useful as marker for endometrial carcinoma (EC ...
Abramić, Marija +4 more
core +1 more source
Metformin as a Therapeutic Target in Endometrial Cancers. [PDF]
Endometrial cancer is the most common gynecologic malignancy in developed countries. Its increasing incidence is thought to be related in part to the rise of metabolic syndrome, which has been shown to be a risk factor for the development of ...
Johnson, Jennifer +6 more
core +2 more sources
Background Endometriosis is assumed to be involved in ovarian cancer development, which is called endometriosis-associated ovarian cancer (EAOC). Uterine endometrial cells may be the cell of origin of EAOC. Accumulated carcinogenic changes in the uterine
Aya Ishizaka +13 more
doaj +1 more source

