Summary: To detect novel endometrial cancer risk variants, we leveraged information from endometrial cancer risk factors in a multi-trait GWAS analysis.
Xuemin Wang+13 more
doaj
Survival outcome in endometrial cancer patients according to hereditary predisposition
Objective: A familial history of ovarian cancer/breast cancer is considered a significant prognostic factor for ovarian cancer. We investigated hereditary factors by examining the incidence of synchronous malignancy in patients with endometrial cancer ...
Heon Jong Yoo+7 more
doaj +1 more source
. Background. Endometrial cancer is one of the most common malignancies of the reproductive system. Effective and cost-effective screening method for populations at high risk is not available.
Guo Zhang+8 more
doaj +1 more source
Risk Assessment of Lymph Node Metastases in Endometrial Cancer Patients: A Causal Approach [PDF]
Assessing the pre-operative risk of lymph node metastases in endometrial cancer patients is a complex and challenging task. In principle, machine learning and deep learning models are flexible and expressive enough to capture the dynamics of clinical risk assessment.
arxiv
The Chinese Expert Consensus Recommendations on Molecular Testing in Endometrial Cancer (2021 edition) [PDF]
Recently, our understanding of the pathogenesis and molecular genetic characteristics of endometrial cancer has been improved along with the development of high-throughput sequencing technology.
The Society of Gynecological Cancer of China Anti-Cancer Association, Chinese Society of Pathology of the Chinese Medical Association, National Pathology Quality Control Center
doaj +1 more source
ECPC-IDS:A benchmark endometrail cancer PET/CT image dataset for evaluation of semantic segmentation and detection of hypermetabolic regions [PDF]
Endometrial cancer is one of the most common tumors in the female reproductive system and is the third most common gynecological malignancy that causes death after ovarian and cervical cancer. Early diagnosis can significantly improve the 5-year survival rate of patients.
arxiv
Multivariate saddlepoint approximations in tail probability and conditional inference [PDF]
We extend known saddlepoint tail probability approximations to multivariate cases, including multivariate conditional cases. Our approximation applies to both continuous and lattice variables, and requires the existence of a cumulant generating function.
arxiv +1 more source
The WID-EC test for the detection and risk prediction of endometrial cancer [PDF]
The incidence of endometrial cancer is rising. Measures to identify women at risk and to detect endometrial cancer earlier are required to reduce the morbidity triggered by the aggressive treatment required for advanced endometrial cancer.
Barrett, James E+23 more
core
Computer-Aided Diagnosis of Low Grade Endometrial Stromal Sarcoma (LGESS) [PDF]
Low grade endometrial stromal sarcoma (LGESS) is rare form of cancer, accounting for about 0.2% of all uterine cancer cases. Approximately 75% of LGESS patients are initially misdiagnosed with leiomyoma, which is a type of benign tumor, also known as fibroids.
arxiv
AXL modulates extracellular matrix protein expression and is essential for invasion and metastasis in endometrial cancer [PDF]
The receptor tyrosine kinase AXL promotes migration, invasion, and metastasis. Here, we evaluated the role of AXL in endometrial cancer. High immunohistochemical expression of AXL was found in 76% (63/83) of advanced-stage, and 77% (82/107) of high-grade
Arif, Batool+15 more
core +2 more sources