Results 41 to 50 of about 4,742,503 (345)

Adjuvant therapy for endometrial cancer in the era of molecular classification: radiotherapy, chemoradiation and novel targets for therapy

open access: yesInternational Journal of Gynecological Cancer, 2020
Endometrial cancer is primarily treated with surgery. Adjuvant treatment strategies for endometrial cancer, such as external beam pelvic radiotherapy, vaginal brachytherapy, chemotherapy, and combined chemotherapy and radiotherapy, have been studied in ...
A. S. V. M. van den Heerik   +4 more
semanticscholar   +1 more source

Risk of cancer after assisted reproduction: a review of the available evidences and guidance to fertility counselors [PDF]

open access: yes, 2018
Infertile women requiring ovarian stimulation and assisted reproduction techniques (ART) are faced with difficult issues. The fear that using hormones could increase their risk of cancer is the most significant.
Codacci-Pisanelli, G   +4 more
core   +1 more source

Endometrial cancer following endometrial resection [PDF]

open access: yesGynecological Surgery, 2007
Endometrial ablation has emerged as a viable alternative to hysterectomy in the treatment of medically intractable dysfunctional uterine bleeding. However, this procedure cannot guarantee complete removal of the entire endometrium. Cases of endometrial cancer after endometrial ablation have been reported in the literature.
Guy Lesec   +10 more
openaire   +3 more sources

Current recommendations and recent progress in endometrial cancer

open access: yesCa, 2019
Endometrial cancer is the most common gynecologic cancer in the United States, and its incidence is rising. Although there have been significant recent advances in our understanding of endometrial cancer biology, many aspects of treatment remain mired in
R. Brooks   +7 more
semanticscholar   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

A Review of Immune Checkpoint Blockade Therapy in Endometrial Cancer.

open access: yesAmerican Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting, 2020
Approximately 30% of primary endometrial cancers are microsatellite instability high/hypermutated (MSI-H), and 13% to 30% of recurrent endometrial cancers are MSI-H or mismatch repair deficient (dMMR).
A. Green, J. Feinberg, V. Makker
semanticscholar   +1 more source

Expression and DNA methylation of 20S proteasome subunits as prognostic and resistance markers in cancer

open access: yesMolecular Oncology, EarlyView.
Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla   +5 more
wiley   +1 more source

Systemic Therapy in Endometrial Cancer: Recent Advances. [PDF]

open access: yes, 2013
Endometrial cancer is a chemosensitive disease. Studies have established a clear benefit of chemotherapy in advanced stages and trials are ongoing to define its role in early stages as well.
Bhise, R   +5 more
core   +1 more source

Molecular Classification and Emerging Targeted Therapy in Endometrial Cancer

open access: yesInternational Journal of Gynecological Pathology, 2020
Recent advances in molecular studies, especially genome-wide analyses, have revealed the landscape of genomic alterations present in endometrial carcinomas, and have provided valuable insight into the pathogenesis of this disease.
T. Yen   +4 more
semanticscholar   +1 more source

Management of Endometrial Cancer

open access: yesInternational Journal of Translation & Community Medicine, 2013
Endometrial cancer (EC) is the most common malignancy of the female genital tract.1 It occurs primarily in postmenopausal women. Overall, about 2.64% of women develop EC during their lifetime. In those patients, the most common presenting symptom is abnormal uterine bleeding. Based on clinical and pathological features, sporadic EC is classified into 2
Androutsopoulos G, Decavalas G
openaire   +1 more source

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