Results 61 to 70 of about 340,092 (249)

Endometrial Assembloid Model Reveals Endometrial Gland Development Regulation by Estradiol‐Driven WNT7B Suppression

Advanced Science, EarlyView.
This study developed a 3D endometrial assembloid model to study how uterine glands form and develop. They discovered key interactions between different cell types and identified WNT7B as a regulator controlled by estradiol‐mediated TGFβ1‐VDR interaction.
Xintong Li, Yanjie Guo, Jianlin Li, Yimeng Li, Leqian Lin, Hoi Kit Matthew Leung, Qingqing Zhang, Kai‐Fai Lee, Ka‐Wang Cheung, Ernest H. Y. Ng, William S. B. Yeung, Philip C. N. Chiu, Cheuk‐Lun Lee   +12 more
wiley   +1 more source

Diagnostic accuracy of hysteroscopic scoring system in predicting endometrial malignancy and atypical endometrial hyperplasia

Journal of Mid-Life Health, 2021
Aims and Objectives: The aim of this study was to determine the diagnostic accuracy of a hysteroscopic scoring system in predicting endometrial cancer and endometrial hyperplasia with atypia.
Bhukya Harika, Murali Subbaiah, Dilip Kumar Maurya   +2 more
doaj   +1 more source

IGF‐1 Deficiency Serves as an Integrated Biomarker Pathogenic Driver and Predictor in Poor Ovarian Response

Advanced Science, EarlyView.
IGF‐1 deficiency underlies poor ovarian response (POR), as reduced levels in follicular fluid and granulosa cells impair antral follicle formation and compromise reproductive outcomes. Including IGF‐1 as a biomarker significantly enhances the accuracy of models predicting both PORrisk and pregnancy success.
Zhu Hu, Yuanyuan Yu, Guanyou Huang, Jinnan Li, Chao Yang, Aizhuan Long, Jia Tang, Tengxiang Chen, Shuyun Zhao, Tuo Zhang   +9 more
wiley   +1 more source

CELL MOTILITY PROTEINS IN ENDOMETRIUM CARCINOMA AND ENDOMETRIAL HYPERPLASIA: ASSOCIATION WITH CANCER RISK

Сибирский онкологический журнал, 2020
Introduction. Proteins associated with cellular motility are known to play an important role in invasion and metastasis of cancer, however there is no evidence of their association with the development of malignant tumors including endometrial cancer (EC)
N. V. Yunusova, L. V. Spirina, A. L. Chernyshova, E. S. Kolegova, E. A. Sidenko, L. A. Kolomiets, I. V. Kondakova   +6 more
doaj   +1 more source

Thyroxine-binding globulin: investigation of microheterogeneity [PDF]

, 1981
Preparations of T4-binding globulin (TBG) from human serum was performed using only two affinity chromatography steps. Purity of the protein was demonstrated by a single band in overloaded disc and sodium dodecyl sulfate electrophoresis, equimolar ...
Gärtner, Roland, Henze, R., Horn, K., Pickardt, C. R., Scriba, Peter Christian   +4 more
core   +1 more source

Preliminary Study on the Value of Contrast‐Enhanced Ultrasound in Enhancing Early Vascular Architecture for the Differential Diagnosis of Benign and Malignant Endometrial Lesions

Journal of Clinical Ultrasound, EarlyView.
This study aimed to analyze the microvascular morphology and distribution (i.e., early vascular architecture) of endometrial carcinoma lesions during the early enhancement phase using contrast‐enhanced ultrasound (CEUS). The results confirmed that quantitative parameters based on the early vascular architecture possess certain diagnostic efficacy for ...
Qiuyun Huang, Yunhao Luo, Jia Xu, Danlin Wen, Fangqin Liu, Jing Miao, Lang Qiao   +6 more
wiley   +1 more source

Serum and tissue angiogenin in patients with endometrial hyperplasia

Middle East Fertility Society Journal, 2010
Objective: To evaluate angiogenin levels in both tissue and serum of patients with endometrial hyperplasia with and without atypia. Methods: Sixty women were classified according to the histopathological findings of endometrium into three groups.
Mohamed Abelsalam Mohamed, Naglaa F. Abraheem   +1 more
doaj   +1 more source

Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research

Mass Spectrometry Reviews, EarlyView.
Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik, Petr Lapcik, Pavla Bouchalova, Pavel Bouchal   +3 more
wiley   +1 more source

How to blow up a massive star [PDF]

, 2016
Unweighted UniFrac distance between benign, hyperplasia, and endometrial cancer cohorts.
Alexis Hokenstad (3575855), Andrea Mariani (495858), Douglas Creedon (3575873), E. Cheek (3575867), Francesco Multinu (3575864), Gary Keeney (3575861), Heidi Nelson (674930), Jun Chen (4238), Marina Walther-Antรณnio (3575876), Nicholas Chia (233775), Tammy Distad (3575870)   +10 more
core   +7 more sources

Differential Expression Patterns of Glycolytic Enzymes and Mitochondria-Dependent Apoptosis in PCOS Patients with Endometrial Hyperplasia, an Early Hallmark of Endometrial Cancer, In Vivo and the Impact of Metformin In Vitro

International Journal on Biological Sciences, 2019
The underlying mechanisms of polycystic ovarian syndrome (PCOS)-induced endometrial dysfunction are not fully understood, and although accumulating evidence shows that the use of metformin has beneficial effects in PCOS patients, the precise regulatory ...
Tao Wang, Jiao Zhang, Min Hu, Yuehui Zhang, P. Cui, Xin Li, Juan Li, Edvin Vestin, M. Brännström, Linus R. Shao, H. Billig   +10 more
semanticscholar   +1 more source