Results 51 to 60 of about 20,476 (195)

ALDH1 expression predicts progression of premalignant lesions to cancer in Type I endometrial carcinomas

Scientific Reports, 2021
In type 1 endometrial cancer, unopposed estrogen stimulation is thought to lead to endometrial hyperplasia which precedes malignant progression. Recent data from our group and others suggest that ALDH activity mediates stemness in endometrial cancer, but
Vei Mah, Yahya Elshimali, Alison Chu, Neda A. Moatamed, Jamar P. Uzzell, Jessica Tsui, Stephen Schettler, Hania Shakeri, Madhuri Wadehra   +8 more
doaj   +1 more source

Laparoscopic ultrasound eXAmination: Analysis of fellow surgeons learning curve in minimally invasive gynecologic procedures (LUXA study)

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective Laparoscopic ultrasound (LUS), performed with an endoscopic ultrasound probe, has shown potential in addressing challenges related to haptic perception and lesion detection in minimally invasive surgery. The aim of the present study was to evaluate the learning curve of gynecologic surgery fellows in achieving competency in LUS image
Maria Teresa Giudice, Francesca Moro, Marianna Ciancia, Consuelo Russo, Diana Giannarelli, Serena Cappuccio, Matteo Loverro, Camilla Fedele, Marco D'Indinosante, Andrea Rosati, Emanuele Perrone, Francesca Ciccarone, Floriana Mascilini, Anna Fagotti, Francesco Fanfani, Antonia C. Testa   +15 more
wiley   +1 more source

Toxic Effects of Bisphenol A and Its Analogs on Ovarian Structure and Function: A Narrative Review of Ovary‐Focused Studies

Journal of Applied Toxicology, EarlyView.
ABSTRACT Bisphenol A (BPA) is a widely used industrial chemical found in polycarbonate plastics and epoxy resins and is recognized for its endocrine‐disrupting properties. Human exposure is common due to its presence in food packaging and everyday products. As BPA use has been restricted, structurally similar compounds such as BPS, BPB, BPAF, and BADGE
Nurbanu Zengin, Marwa Tawfıq Ahmed Alsalım, Muhammed Canik, Sevda Bağdatlı, Nazan Deniz Yön   +4 more
wiley   +1 more source

Peri‐ and Post‐Menopausal Hormone Replacement Therapy and Voice Disorder Risk: A TriNetX Study

The Laryngoscope, EarlyView.
ABSTRACT Objectives The aim of this study was to elucidate the risk of developing voice disorders among peri‐ and post‐menopausal female hormone replacement therapy (HRT) users. Methods A retrospective cohort study was conducted using the TriNetX Global Collaborative Network.
David Kayekjian, Warren B. Chun, Shaun A. Nguyen, Ashli K. O'Rourke, Kirsten D. Meenan   +4 more
wiley   +1 more source

Modern approaches to the diagnosis of endometrial hyperplasia

Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье
Introduction. In recent years, there has been an increase in the frequency of various nosological forms of endometrial hyperplasia, which is diagnosed in 38-72% of women of reproductive age.
M. M. Damirov, O. B. Yurchenko, G. P. Titova, N. V. Borovkova, A. P. Ierusalimskiy   +4 more
doaj   +1 more source

Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research

Mass Spectrometry Reviews, EarlyView.
Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik, Petr Lapcik, Pavla Bouchalova, Pavel Bouchal   +3 more
wiley   +1 more source

Concurrent and future risk of endometrial cancer in women with endometrial hyperplasia: A systematic review and meta-analysis.

PLoS ONE, 2020
BackgroundTo inform treatment decisions in women diagnosed with endometrial hyperplasia, quantification of the potential for concurrent endometrial cancer and the future risk of progression to cancer is required.MethodsWe identified studies up to ...
Michelle T Doherty, Omolara B Sanni, Helen G Coleman, Chris R Cardwell, W Glenn McCluggage, Declan Quinn, James Wylie, Úna C McMenamin   +7 more
doaj   +1 more source

Promotion of the occurrence of endometrioid carcinoma by S100 calcium binding protein P

BMC Cancer, 2020
Background Endometrial cancer, one of the most common malignant tumors, is a serious threat to women’s health. Endometrial hyperplasia is a precursor of endometrial cancer.
Dan Zhang, Xiuying Chen, Hexia Xia, Lu Wang, Hongbo Zhao, Bufang Xu, Aijun Zhang, Wei Zhang   +7 more
doaj   +1 more source

Association of Glucagon‐Like Peptide‐1 Receptor Agonists With Cancer Risk in Older Adults With Type 2 Diabetes

Obesity, EarlyView.
ABSTRACT Objective The real‐world evidence on the association between glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs) and cancer risk remains limited and mixed. Methods In 2013–2020 national Medicare claims data, we included cancer‐naïve patients with type 2 diabetes (T2D). We identified those who initiated GLP‐1 RA, sodium‐glucose cotransporter 2
Ying Lu, Hao Dai, Huilin Tang, William T. Donahoo, Thomas J. George, Ramon C. Sun, Sizun Jiang, Aik Choon Tan, Yi Guo, Jonathan D. Licht, John M. Allen, Kelvin P. Lee, Jingchuan Guo, Jiang Bian   +13 more
wiley   +1 more source

Advent of NK3R Antagonists for the Treatment of Menopausal Hot Flushes: A Narrative Review

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT The menopause transition is marked by symptoms predominantly attributed to declining oestrogen levels. Approximately 80% of women experience associated symptoms, and 25% experience severe symptoms. The commonest are vasomotor symptoms (VMS), collectively referring to hot flushes and/or night sweats.
Aaran H. Patel, Aureliane Pierret, Edouard G. Mills, Alexander N. Comninos, Waljit S. Dhillo, Ali Abbara   +5 more
wiley   +1 more source