Results 51 to 60 of about 172,372 (215)

Herbal Therapeutics in Osteoporosis: Mechanisms, Evidence, and Translational Potential

Phytotherapy Research, EarlyView.
Schematic overview of bone remodeling dysregulation in osteoporosis and the multi‐target protective role of herbal therapeutics. ABSTRACT Osteoporosis is a chronic bone disease marked by reduced density and increased fracture risk. Current treatments face limitations in safety, efficacy, and long‐term adherence, prompting interest in alternative ...
Elnaz Vafadar Moradi, Sina Vossoughinia, Zahra Yazdanpanah, Hossein Sobhani, Jalileh Jalali, Mahboobeh Ghasemzadeh Rahbardar   +5 more
wiley   +1 more source

Future Challenges and Opportunities for the Viability of Animal Populations in Zoos and Aquariums

Zoo Biology, EarlyView.
ABSTRACT Maintaining sustainable animal populations is fundamental to zoo and aquarium missions in education, visitor engagement, entertainment, scientific advancement, public health and wellbeing, advocacy, and conservation impact. Yet, sustaining viable populations remains a persistent challenge.
Lisa J. Faust, John E. Andrews, Alex Ball, Rebecca Biddle, Rachel A. Bladow, Asako Y. Chaille, Marie Corlay, Veronica Cowl, Caitlin Curry, Candice Dorsey, J. Andrew DeWoody, Adam Eyres, Gina M. Ferrie, Elmar Fienieg, Ashley D. Franklin, Emily K. Latch, Andrea Putnam, Kristine Schad Eebes, Leah J. Williams   +18 more
wiley   +1 more source

Advent of NK3R Antagonists for the Treatment of Menopausal Hot Flushes: A Narrative Review

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT The menopause transition is marked by symptoms predominantly attributed to declining oestrogen levels. Approximately 80% of women experience associated symptoms, and 25% experience severe symptoms. The commonest are vasomotor symptoms (VMS), collectively referring to hot flushes and/or night sweats.
Aaran H. Patel, Aureliane Pierret, Edouard G. Mills, Alexander N. Comninos, Waljit S. Dhillo, Ali Abbara   +5 more
wiley   +1 more source

Risk of Cancer With Hormone Replacement Therapy: A Narrative Review

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Hormone replacement therapy (HRT) remains the cornerstone of menopausal symptom management, effectively alleviating vasomotor symptoms and genitourinary syndrome, whilst mitigating long‐term risks such as osteoporosis. However, despite an increasing body of evidence on the relative safety of HRT, earlier studies that demonstrated an increased ...
Gabriella Yongue, Zachary Nash, Vikram Talaulikar, Shibani Nicum   +3 more
wiley   +1 more source

Modern approaches to the diagnosis of endometrial hyperplasia

Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье
Introduction. In recent years, there has been an increase in the frequency of various nosological forms of endometrial hyperplasia, which is diagnosed in 38-72% of women of reproductive age.
M. M. Damirov, O. B. Yurchenko, G. P. Titova, N. V. Borovkova, A. P. Ierusalimskiy   +4 more
doaj   +1 more source

Basophils in Immunity: Activation Pathways, Roles in Allergy and AllergoOncology and Application of the Basophil Activation Test

Allergy, EarlyView.
ABSTRACT Basophils, the least abundant leukocytes, are increasingly recognised as potent immunomodulators. Upon activation, they rapidly release preformed granule‐associated mediators including histamine and lipid mediators such as LTC4, while cytokine production occurs over a longer timescale, contributing to downstream immune responses.
Jitesh Chauhan, Sofia Vlasova, Alicia Chenoweth, Debra H. Josephs, Heather J. Bax, Sophia N. Karagiannis   +5 more
wiley   +1 more source

The effect of age on prediction of concurrent endometrial cancer in patients with atypical endometrial hyperplasia

, 2020
Purpose: To evaluate the effect of age on prediction of concurrent endometrial cancer (EC) in patients with atypical endometrial hyperplasia (AEH).
Cakmak, Yusuf, ÖGE, TUFAN
core   +1 more source

Risk factors for infection after hysterectomy for benign disease

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
Pre‐ and perioperative risk factors; including high BMI, immunomodulatory treatment, endometriosis, younger age, and previous abdominal or cesarean surgery can be integrated into clinical risk assessment to identify women at increased risk of postoperative infectious morbidity and to guide individualized preventive strategies after hysterectomy ...
Sophia Ehrström, Karin Källén, Andrea Stuart   +2 more
wiley   +1 more source

Telomeres and telomerase in endometrial cancer and hyperplasia

Introduction The study aimed to measure telomeres length (TL) and telomerase expression in normal endometrium and endometrial hyperplasia and cancer. Material and methods Total RNA and DNA were isolated from endometrium samples of 117 patients.
Anna Pańczyszyn, Karolina Włodarczyk, Ewa Boniewska-Bernacka, Iwona Wertel, Anna Goc   +4 more
core   +1 more source

ALDH1 expression predicts progression of premalignant lesions to cancer in Type I endometrial carcinomas

Scientific Reports, 2021
In type 1 endometrial cancer, unopposed estrogen stimulation is thought to lead to endometrial hyperplasia which precedes malignant progression. Recent data from our group and others suggest that ALDH activity mediates stemness in endometrial cancer, but
Vei Mah, Yahya Elshimali, Alison Chu, Neda A. Moatamed, Jamar P. Uzzell, Jessica Tsui, Stephen Schettler, Hania Shakeri, Madhuri Wadehra   +8 more
doaj   +1 more source