Results 31 to 40 of about 94,813 (337)

Systematic assessment of HER2/neu in gynecologic neoplasms, an institutional experience. [PDF]

open access: yes, 2016
BackgroundHER2/neu overexpression and/or amplification has been widely studied in a number of solid tumors, primarily in the breast. In gynecologic neoplasms, determination of HER2/neu status has not been well studied as a predictive biomarker in anti ...
Apple, Sophia K   +5 more
core   +2 more sources

Association of endometrioid ovarian carcinoma arising from endometriosis, endometrioid endometrial carcinoma, and high-grade undifferentiated endometrial sarcoma. a case report [PDF]

open access: yes, 2017
Endometriosis is a chronic disease that affects women of reproductive age. Malignant transformation in endometriosis is considered to be an unusual event, only occurring in 0.7-0.1% of cases.
Caserta, D.   +3 more
core   +1 more source

Endometrial Stromal Hyperplasia: An Underrecognized Condition

open access: yesCase Reports in Pathology, 2013
Hyperplasia of the endometrial stroma is a poorly recognized lesion, lacking widespread recognition with most, if not all, such cases sequestrated in the literature as endometrial stromal nodules or low-grade endometrial stromal sarcomas.
Efthimios Sivridis   +2 more
doaj   +1 more source

Concurrent endometrial intraepithelial carcinoma (EIC) and endometrial hyperplasia

open access: yesHuman Pathology: Case Reports, 2015
Endometrial cancer is one of the most common gynecological neoplasms in the United States. It is divided into type I and type II carcinomas based on histological features.
Steven Wang, MD   +2 more
doaj   +1 more source

The incidence and survival of cervical, ovarian, and endometrial cancer in Korea, 1999-2017: Korea Central Cancer Registry [PDF]

open access: yesObstetrics & Gynecology Science, 2021
Objective The three major gynecologic cancers are cervical, endometrial, and ovarian cancer. This study aimed to describe the 19-year trends and survival rates in cervical, endometrial, and ovarian cancer in a Korean female population.
Hyeong In Ha   +5 more
doaj   +1 more source

Immunotherapy in gynecological cancers

open access: yesExploration of Targeted Anti-tumor Therapy, 2021
Immunotherapy has changed the natural history of several malignancies that, a decade ago, had a very poor prognosis, such as lung cancer and melanoma.
Domenica Lorusso   +8 more
doaj   +1 more source

ARID1A and PI3-kinase pathway mutations in the endometrium drive epithelial transdifferentiation and collective invasion

open access: yesNature Communications, 2019
PIK3CA mutations and ARID1A loss co-exist in endometrial neoplasms. Here, the authors show that these co-mutations drive gene expression profiles correlated with differential chromatin accessibility and ARID1A binding in the endometrial epithelium ...
Mike R. Wilson   +15 more
doaj   +1 more source

Occupational exposure to pesticides and endometrial cancer in the Screenwide case-control study

open access: yesEnvironmental Health, 2023
Background Endometrial cancer is the most common gynaecological tumour in developed countries and disease burden is expected to increase over the years. Identifying modifiable risk factors may help developing strategies to reduce the expected increasing ...
Arnau Peñalver-Piñol   +22 more
doaj   +1 more source

Endometrial thickness cut-off value by transvaginal ultrasonography for screening of endometrial pathology in premenopausal and postmenopausal women [PDF]

open access: yesObstetrics & Gynecology Science, 2019
ObjectiveTo assess the clinical usefulness and diagnostic accuracy of ultrasonographic measurement of endometrial thickness (ET) in women with endometrial hyperplasia or cancer (EH+).MethodsThis retrospective cohort study included 29,995 consecutive ...
Yu Ran Park   +6 more
doaj   +1 more source

Physiopathological Implications of 7TM Receptors [PDF]

open access: yes, 2010
Seven-transmembrane (7TM) receptors are one of the most important proteins involved in perception of extracellular stimuli and regulation of variety of intracellular signaling pathways.
Cygankiewicz, Adam
core   +1 more source

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