Systematic assessment of HER2/neu in gynecologic neoplasms, an institutional experience. [PDF]
, 2016 BackgroundHER2/neu overexpression and/or amplification has been widely studied in a number of solid tumors, primarily in the breast. In gynecologic neoplasms, determination of HER2/neu status has not been well studied as a predictive biomarker in anti ...
Apple, Sophia K +5 more
core +2 more sources
Non-atypical endometrial hyperplasia: risk factors for occult endometrial atypia and malignancy in patients managed with hysterectomy [PDF]
Obstetrics & Gynecology Science, 2021 Objective To determine the risk factors for occult endometrial atypia and malignancy in patients diagnosed with non-atypical endometrial hyperplasia (NEH) on endometrial biopsy.
Lee Shi Hui +6 more
doaj +1 more source
Association of endometrioid ovarian carcinoma arising from endometriosis, endometrioid endometrial carcinoma, and high-grade undifferentiated endometrial sarcoma. a case report [PDF]
, 2017 Endometriosis is a chronic disease that affects women of reproductive age. Malignant transformation in endometriosis is considered to be an unusual event, only occurring in 0.7-0.1% of cases.
Caserta, D. +3 more
core +1 more source
Endometrial Stromal Hyperplasia: An Underrecognized Condition
Case Reports in Pathology, 2013 Hyperplasia of the endometrial stroma is a poorly recognized lesion, lacking widespread recognition with most, if not all, such cases sequestrated in the literature as endometrial stromal nodules or low-grade endometrial stromal sarcomas.
Efthimios Sivridis +2 more
doaj +1 more source
Concurrent endometrial intraepithelial carcinoma (EIC) and endometrial hyperplasia
Human Pathology: Case Reports, 2015 Endometrial cancer is one of the most common gynecological neoplasms in the United States. It is divided into type I and type II carcinomas based on histological features.
Steven Wang, MD +2 more
doaj +1 more source
Low-Grade Appendiceal Mucinous Neoplasm Involving the Endometrium and Presenting with Mucinous Vaginal Discharge. [PDF]
, 2016 Primary appendiceal mucinous lesions are uncommon and represent a spectrum from nonneoplastic mucous retention cysts to invasive adenocarcinoma. Low-grade appendiceal mucinous neoplasms (LAMNs) represent an intermediate category on this spectrum and can ...
Baumgartner, Joel M +4 more
core +4 more sources
The incidence and survival of cervical, ovarian, and endometrial cancer in Korea, 1999-2017: Korea Central Cancer Registry [PDF]
Obstetrics & Gynecology Science, 2021 Objective The three major gynecologic cancers are cervical, endometrial, and ovarian cancer. This study aimed to describe the 19-year trends and survival rates in cervical, endometrial, and ovarian cancer in a Korean female population.
Hyeong In Ha +5 more
doaj +1 more source
Nature Communications, 2019 PIK3CA mutations and ARID1A loss co-exist in endometrial neoplasms. Here, the authors show that these co-mutations drive gene expression profiles correlated with differential chromatin accessibility and ARID1A binding in the endometrial epithelium ...
Mike R. Wilson +15 more
doaj +1 more source
Occupational exposure to pesticides and endometrial cancer in the Screenwide case-control study
Environmental Health, 2023 Background Endometrial cancer is the most common gynaecological tumour in developed countries and disease burden is expected to increase over the years. Identifying modifiable risk factors may help developing strategies to reduce the expected increasing ...
Arnau Peñalver-Piñol +22 more
doaj +1 more source
Immunotherapy in gynecological cancers
Exploration of Targeted Anti-tumor Therapy, 2021 Immunotherapy has changed the natural history of several malignancies that, a decade ago, had a very poor prognosis, such as lung cancer and melanoma.
Domenica Lorusso +8 more
doaj +1 more source