Results 91 to 100 of about 271,919 (259)

LncRNA NEAT1 affects endometrial receptivity by regulating HOXA10 promoter activity

Cell Cycle, 2022
In vitro fertilization and embryo transfer (IVF-ET) is one of the effective methods to treat female infertility. Poor endometrial receptivity (ER) is an important factor leading to embryo implantation dysfunction, which can reduce pregnancy rate of IVF ...
Jiaxuan Geng, Chenchen Cui, Yisha Yin, Yan Zhao, Cuilian Zhang   +4 more
semanticscholar   +1 more source

Fibroids and infertility

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract The presence of uterine fibroids impacts fertility through multiple mechanisms. While subserosal fibroids have minimal impact, especially when of reduced size, the presence of intramural fibroids impacts both the likelihood of pregnancy and its outcomes.
Edgar Mocanu, Basil Tarlatzis, Dov Feldberg, Ivonne Diaz, Christina O'Brien, Nikhil Purandare   +5 more
wiley   +1 more source

VIP contribution to the decidualization program: regulatory T cell recruitment [PDF]

, 2014
During early pregnancy, the human uterus undergoes profound tissue remodeling characterized by leukocyte invasion and production of proinflammatory cytokines, followed by tissue repair and tolerance maintenance induction.
Agüero, Mariana, Grasso, Esteban Nicolas, Mor, Gil, Paparini, Daniel Esteban, Perez Leiros, Claudia, Ramhorst, Rosanna Elizabeth   +5 more
core   +1 more source

The Combined Use of Medium- and Short-Chain Fatty Acids Improves the Pregnancy Outcomes of Sows by Enhancing Ovarian Steroidogenesis and Endometrial Receptivity

Nutrients, 2022
Fatty acids play important roles in maintaining ovarian steroidogenesis and endometrial receptivity. Porcine primary ovarian granulosa cells (PGCs) and endometrial epithelial cells (PEECs) were treated with or without medium- and short-chain fatty acids (
Xiangzhou Zeng, Siyu Li, Qianhong Ye, S. Cai, Shuang Quan, Lu Liu, Shihai Zhang, Fang Chen, C. Cai, Fenglai Wang, S. Qiao, Xiangfang Zeng   +11 more
semanticscholar   +1 more source

COL1A1+ Epithelial Cells Orchestrate VEGFA‐VEGFR Signaling in Endometritis Revealed by Single‐Cell Analysis

Journal of Clinical Laboratory Analysis, EarlyView.
Single‐cell RNA‐seq of normal and endometritis endometrium shows reduced epithelial cells and fate divergence toward ferroptosis or ribosome/antigen‐presentation programs. COL1A1+ epithelial cells act as an AP‐1–driven hub that enhances VEGFA–VEGFR signaling and remodels the vascular microenvironment.
Chengzi Tian, Zaiyi Li
wiley   +1 more source

Transcriptomics of receptive endometrium in women with sonographic features of adenomyosis

Reproductive Biology and Endocrinology, 2022
Background Women with uterine adenomyosis seeking assisted reproduction have been associated with compromised endometrial receptivity to embryo implantation.
Erika Prašnikar, Tanja Kunej, Mario Gorenjak, Uroš Potočnik, Borut Kovačič, Jure Knez   +5 more
doaj   +1 more source

Trophinin and integrin β3 expression in the human endometrium. A pilot study [PDF]

, 2011
The study involved ten patients with tubal factor infertility. Patients (Group I, age 28–34 years, n=5; Group II, age 35–40 years, n=5) underwent endometrial biopsy on postovulatory days 7–10 of the natural menstrual cycle.
Arend, Andres, Aunapuu, Marina, Kibur, Ragnar Toomas, Männik, Piret   +3 more
core   +3 more sources

The Application Value of Transvaginal Three‐Dimensional Ultrasonography in the Diagnosis of Adenomyosis of the Uterus

Journal of Clinical Ultrasound, EarlyView.
In this study, 3D‐TVS measurements of the uterine junction zone (JZ) in 120 patients showed that a JZmax threshold of ≥ 0.45 cm yielded 77% sensitivity and 89% specificity for adenomyosis diagnosis. Notably, JZ thickness varies minimally with age, demonstrating its stability and excellent diagnostic performance.
Mengyu Li, Zhen Zong, Xiaoman Wang, Hebin Zhang   +3 more
wiley   +1 more source

Progestins Related to Progesterone and Testosterone Elicit Divergent Human Endometrial Transcriptomes and Biofunctions. [PDF]

, 2020
Progestins are widely used for the treatment of gynecologic disorders and alone, or combined with an estrogen, are used as contraceptives. While their potencies, efficacies and side effects vary due to differences in structures, doses and routes of ...
Balayan, Shayna, Chen, Joseph C, Giudice, Linda C, Greenblatt, Ruth M, Houshdaran, Sahar, Irwin, Juan C, Smith-McCune, Karen, Vallvé-Juanico, Júlia, Vo, Kim Chi   +8 more
core   +2 more sources

Commercially Available Molecular Approaches to Evaluate Endometrial Receptivity: A Systematic Review and Critical Analysis of the Literature

Diagnostics, 2022
Despite the advances in the field of reproductive medicine, implantation failure represents a challenging condition affecting 10–30% of patients subjected to in vitro fertilization (IVF).
E. Maziotis, T. Kalampokas, P. Giannelou, S. Grigoriadis, A. Rapani, Marios Anifantakis, A. Kotsifaki, A. Pantou, Olga Triantafyllidou, Despoina Tzanakaki, Spyridoula Neofytou, P. Vogiatzi, P. Bakas, M. Simopoulou, N. Vlahos   +14 more
semanticscholar   +1 more source