Results 121 to 130 of about 271,919 (259)

Hashimoto’s thyroiditis impairs embryo implantation by compromising endometrial morphology and receptivity markers in euthyroid mice

open access: yesReproductive Biology and Endocrinology, 2019
Background Although thyroid dysfunction caused by Hashimoto’s thyroiditis (HT) is believed to be related to implantation failure due to the underdevelopment of the receptive uterus, it is unknown whether HT itself, even in the euthyroid state, impairs ...
Zhangbi Wu   +10 more
doaj   +1 more source

Pulse of inflammatory proteins in the pregnant uterus of European polecats (Mustela putorius) leading to the time of implantation [PDF]

open access: yes, 2017
Uterine secretory proteins protect the uterus and conceptuses against infection, facilitate implantation, control cellular damage resulting from implantation, and supply pre-implantation embryos with nutrients.
Burchmore, Richard J.S.   +2 more
core   +1 more source

Development of CAR Exosomes Targeting FAP for the Treatment of Intrauterine Adhesion

open access: yesJournal of Extracellular Vesicles, Volume 15, Issue 5, May 2026.
ABSTRACT Engineered extracellular vesicles (EVs) have emerged as promising cell‐free platforms for immunomodulation and tissue repair. In this study, we generated EVs derived from chimeric antigen receptor (CAR) T cells targeting fibroblast activation protein (FAP) and investigated their biological and therapeutic functions.
Wenyan Fu   +8 more
wiley   +1 more source

Human endometrial receptivity and embryo-endometrium interactions [PDF]

open access: yes, 2011
Infertility is an increasing medical and social problem affecting more than 10% of couples worldwide. Many underlying causes of human infertility have been overcome by assisted reproductive techniques; nevertheless, the implantation process remains one
Altmäe, Signe
core   +1 more source

Bacterial Extracellular Vesicles: New Hype or Hope to Explain Reproductive Host–Microbiota Interactions

open access: yesJournal of Extracellular Vesicles, Volume 15, Issue 5, May 2026.
ABSTRACT Rapid advances in microbiome research are transforming our understanding of human health and disease, with growing focus on the female reproductive tract as a critical but understudied niche. Evidence for a local microbiome largely derives from bacterial nucleic acid detection; however, the biological relevance of these signals remains debated,
Hannah Wein   +5 more
wiley   +1 more source

Age‐Dependent Alterations of Chromosomal Passenger Complex Members During Implantation and Decidualization in the Mouse Uterus

open access: yesAging Cell, Volume 25, Issue 5, May 2026.
Aging in females reduces the number of implantation sites and leads to specific, compartment‐dependent changes in components of the chromosomal passenger complex (pIncenp, Aurora B, Survivin, Borealin) during mouse uterine implantation and decidualization.
Ezgi Golal, Cemre Nur Balci, Nuray Acar
wiley   +1 more source

HDAC3 Regulates Transcriptional Networks Governing Decidualization

open access: yesThe FASEB Journal, Volume 40, Issue 8, 30 April 2026.
HDAC3 orchestrates transcriptional programs essential for uterine decidualization. Loss of HDAC3 disrupts cytoskeletal organization, metabolic signaling, and oxidative stress responses, impairing stromal cell differentiation and decidualization. These alterations compromise uterine receptivity and result in failed embryo implantation.
Loan Thi Kim Nguyen   +5 more
wiley   +1 more source

Cellular and molecular basis for endometriosis-associated infertility [PDF]

open access: yes, 2012
Endometriosis is a gynecological disease characterized by the presence of endometrial glandular epithelial and stromal cells growing in the extra-uterine environment.
Julie A. Birt   +2 more
core   +1 more source

Innate Immunity and Microbial Recognition in Reproduction: From Barrier Defense to Maternal–Fetal Tolerance

open access: yesThe FASEB Journal, Volume 40, Issue 8, 30 April 2026.
Graphical abstract illustrating the barrier defense–tolerance framework of reproductive innate immunity. Across the female and male reproductive tracts and the maternal–fetal interface, epithelial barriers, innate sensors, immune cells, and microbial signals are integrated to preserve reproductive homeostasis.
Xianlin Rao   +3 more
wiley   +1 more source

LEFTY2 inhibits endometrial receptivity by downregulating Orai1 expression and store-operated Ca²+ entry

open access: yes, 2017
Early embryo development and endometrial differentiation are initially independent processes, and synchronization, imposed by a limited window of implantation, is critical for reproductive success. A putative negative regulator of endometrial receptivity
Alauddin, M   +14 more
core   +1 more source

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