Results 181 to 190 of about 4,542,677 (277)

Endometrial Stromal Cells from Endometriosis Patients Reflect Lesion-Type-Specific Heterogeneity. [PDF]

Cells
Rodriguez Gutierrez D, Spalinger MR, Astourian A, Evrova O, Berclaz L, Hartmann M, Dedes I, Imesch P, Metzler JM, Witzel I, Shilaih M, Vongrad V, Leeners B.   +12 more
europepmc   +1 more source

Estradiol Promotes Tumor Progression in ERα‐Low Endometrial Cancer via the GPER/SphK1 Pathway

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 10, October 2026.
Estradiol (E2) promotes tumor progression in ERα‐low endometrial cancer through the GPER/SphK1/ERK1/2 signaling axis. E2 binding to GPER activates SphK1 and downstream ERK1/2, upregulating Cyclin D1, Cyclin E1, and MMP‐9 to drive cell proliferation, migration, and invasion.
Xiuwen Wang, Haofei Sun, Xin Wen, Weiwei Xin, Zhandong Hu, Zhongwei Zhao, Lizhi Zhang   +6 more
wiley   +1 more source

Establishment of a xenograft model of endometriosis-associated fibrosis using human immortalized endometrial stromal cells overexpressing HOXC8. [PDF]

Sci Rep
Takasaki-Kawasaki H, Sato S, Tamehisa T, Yoneda T, Shiroshita A, Fujimura T, Tamura I, Maekawa R, Sugino N.   +8 more
europepmc   +1 more source

Association Between Preoperative Dyslipidemia and the Prognosis of Patients With Endometrial Cancer: A Retrospective Cohort Study

The Kaohsiung Journal of Medical Sciences, Volume 42, Issue 10, October 2026.
ABSTRACT Endometrial cancer (EC) is closely related to metabolic disorders. We aimed to investigate whether preoperative dyslipidemia independently affects the prognosis of patients with EC. One hundred and ninety‐four women diagnosed with EC by pathology and who had undergone standardized surgical treatment at the Affiliated Hospital of Jining Medical
Song Li, Rong‐He Sun, Qing Chen, Zeng‐Shu Huang, Yun‐Fei Wang, Chang‐Zhong Li   +5 more
wiley   +1 more source

Rubiadin, as a key metabolite of the Bushen Huoxue formula, promotes apoptosis of endometrial stromal cells and improves intrauterine adhesions by activating the AMPK/p53/p21 pathway. [PDF]

Front Pharmacol
Shen C, Sha C, Yang M, Lin Y, Ma J, Shen D, Zhang B, Qi C, Zhang Q, Zhang X.   +9 more
europepmc   +1 more source

Organoids: Current Applications and Future Directions

MedComm, Volume 7, Issue 10, October 2026.
Organoids are three‐dimensional multicellular structures derived from stem cells or primary tissues that recapitulate key structural and functional features of native organs. Advances in stem cell biology, biomaterials, and bioengineering have established organoids as powerful platforms for studying human development and disease mechanisms, drug ...
Yueqi Leng, Yue Wang, Canhui Cao, Feng Deng, Weisi Lian, Xingtong Chen, Mingmei Lin, Zhonghong Zeng, Dan Mo, Shangqi Li, Yilei He, Yang Yu, Heng Pan, Ping Zhou, Rong Li   +14 more
wiley   +1 more source

Progesterone receptor isoform modulation via enhancer activation regulates progesterone signaling in endometrial stromal cells. [PDF]

F S Sci
Montague Redecke SG, Bell-Hensley A, Yi M, Li S, DeMayo FJ.   +4 more
europepmc   +1 more source

Mesothelin as Biomarker and Therapeutic Target for Immunotherapy in Cancer

MedComm, Volume 7, Issue 10, October 2026.
Mesothelin overexpression activate important pathways like nuclear factor k‐light‐chain‐enhancer of activated B cells (NF‐κB) and interleukin‐6 (IL‐6). This in turn causes numerous cancers, such as pancreatic and ovarian cancers. MSLN‐targeting immunotherapies, like monoclonal antibodies, have shown efficacy.
Manoj Kumar Gupta, Ramakrishna Vadde, Ganji Purnachandra Nagaraju   +2 more
wiley   +1 more source

Preparation of <i>Artemisia argyi</i>-Derived Extracellular Nanovesicles and Their Protective Effects Against Oxidative Stress-Induced Senescence in Endometrial Stromal Cells. [PDF]

Bioengineering (Basel)
Zheng X, Huang R, Liu Z, Liu T, Lin H, Yin L, Wu Q, Zhao M.   +7 more
europepmc   +1 more source

Targeting the DNA Damage Response in Cancer

MedComm, Volume 7, Issue 10, October 2026.
Targeting the DNA damage response (DDR) reshapes both tumor vulnerability and antitumor immunity. DNA lesions and DDR inhibitors can promote cytosolic nucleic‐acid sensing, antigen presentation, and immune activation, but can also induce adaptive immune escape.
Yihuan Qiao, Boyu Kang, Jian Zhang, Rui Zhang, Jipeng Li   +4 more
wiley   +1 more source