Results 121 to 130 of about 55,351 (242)

Modular determinants of cleavage preference in GIY-YIG nucleases revealed by block-based DNA shuffling and directed evolution. [PDF]

Nucleic Acids Res
Loedige KW, Hall MA, Ghimirey S, Stead BE, Edgell DR.   +4 more
europepmc   +1 more source

KU80 suppresses endonuclease G activity to preserve genomic integrity

The FEBS Journal, EarlyView.
Under normal conditions, EndoG remains restricted to mitochondria and the genome remains intact. When KU80 is absent, EndoG translocates into the nucleus, where it promotes DNA fragmentation and genomic instability. Thus, this work highlights the importance of KU80 in tightly controlling EndoG localization to preserve genome stability.
Jargalan Batsaikhan, Kwang‐Hyun Park, Hae Ryung Chang, Eunyoung Jung, Myung‐Jin Kim, Jeeyoon Kang, Hyunjo Shim, Eui‐Jeon Woo, Yonghwan Kim   +8 more
wiley   +1 more source

Molecular Characterization of a Restriction Endonuclease PsaI from <i>Pseudomonas anguilliseptica</i> KM9 and Sequence Analysis of the PsaI R-M System. [PDF]

Int J Mol Sci
Furmanek-Blaszk B, Mruk I, Sektas M.
europepmc   +1 more source

Periodontitis and Periodontal Conditions in Systemically Healthy Children and Adolescents

Journal of Clinical Periodontology, EarlyView.
ABSTRACT Objective To answer the PICoS question ‘in systemically healthy children and adolescents (Population), what are the main features of periodontitis, necrotising periodontal diseases (NPD) and other periodontal conditions (periodontal abscesses, endo‐periodontal lesions, traumatic occlusal forces, prosthesis‐ and tooth‐related factors ...
Inbar Eshkol‐Yogev, Nagore Ambrosio, Cheryl Somani, Elena Figuero, Lior Shapira, Janet Davies   +5 more
wiley   +1 more source

Comprehensive genome analysis uncovers the diversity of jumbo phages in the pig gut microbiome. [PDF]

Front Vet Sci
Wei C, Chen Z.
europepmc   +1 more source

Pentatricopeptide repeat proteins in crops: Advances in functional mechanisms and breeding applications

Journal of Integrative Plant Biology, EarlyView.
Pentatricopeptide repeat proteins coordinate nucleus‐organelle communication by modulating RNA metabolism within chloroplasts and mitochondria. This review highlights how they control critical processes like photosynthesis, seed development, fertility restoration, and stress survival in crops, and explores their potential as programmable tools for RNA ...
Mingming Wu, Maohong Cai, Rongrong Zhai, Jing Ye, Guofu Zhu, Faming Yu, Shenghai Ye, Xiaoming Zhang   +7 more
wiley   +1 more source

Functions and applications of enzymes in nucleic acid nanotechnology. [PDF]

J Nanobiotechnology
Rong Q, Chu Z, Xu Y, Ma L, Wang L, Wang S, Yin Z, Su X.   +7 more
europepmc   +1 more source

The annotated blueprint: integrated functional genomic resources for a model tetraploid wheat Triticum turgidum cv Kronos

New Phytologist, EarlyView.
Summary Triticum turgidum cv Kronos is a tetraploid wheat cultivar that underpins one of the most widely used community platforms for functional genomics. Over the past decade, researchers have generated c. 3000 exome‐capture (EC) and promoter‐capture (PC) datasets linked to mutagenized seed stocks, along with extensive transcriptomic and phenotypic ...
Kyungyong Seong, Rakesh Kumar, Daniil M. Prigozhin, China Lunde, Thales Henrique Cherubino Ribeiro, Sébastien Bélanger, Jo‐Wei Allison Hsieh, McCree Tang, Blake C. Meyers, Ksenia V. Krasileva   +9 more
wiley   +1 more source

It's not me, it's you: Anti-phage nuclease specificity inside a bacterium. [PDF]

PLoS Pathog
Hong A, Bondy-Denomy J.
europepmc   +1 more source

Stabilisation of Tomato Yellow Leaf Curl China Virus Infectious Clones Through Micro‐Homology Mediated End Joining

Plant Biotechnology Journal, EarlyView.
ABSTRACT Tomato yellow leaf curl China virus (TYLCCNV) is a major agricultural pathogen and primary model for circular single‐stranded DNA (cssDNA) virus studies. The infectious clones of TYLCCNV and other cssDNA viruses are usually constructed as two tandem copies of the small viral genomes in Agrobacterium‐mediated T‐DNA vectors.
Anxiang Wang, Tian Meng, Ju Wang, Xiaomei Xu, Dan Li, Zhanqing Lv, Aiqi Yan, Mian Zhou, Bo Ding, Qiuying Yang   +9 more
wiley   +1 more source