Results 151 to 160 of about 55,351 (242)

Expression characteristics of dual‐specificity phosphatase 2 and hypoxia‐inducible factor‐1α in acute kidney injury and preliminary study of the effect of dual‐specificity phosphatase 2 on HK‐2 cells

Experimental Physiology, EarlyView.
ABSTRACT Acute kidney injury (AKI) is a global health problem with significant long‐term harm if the prognosis is poor. Dual‐specificity phosphatase 2 (DUSP2) is involved in key regulatory pathways in several disease processes, but its function in renal pathophysiology is unclear.
Xueqian Chu, Songmin Xue, Lanyan Lin, Xuan Huang, Sisi Chen, Wulaer Adeli, Zulibiya Tuohetiyaer, Suhua Li, Chen Lu   +8 more
wiley   +1 more source

Structural basis of substrate diversity and functional evolution of archaeal RNA-splicing endonucleases. [PDF]

Nucleic Acids Res
Miyata Y, Yamagami R, Kawamura T, Hori H, Hirata A.   +4 more
europepmc   +1 more source

Population Pharmacokinetic and Exposure‐Efficacy Analysis of Baloxavir Marboxil for Influenza Treatment and Post‐Exposure Prophylaxis in Children

Clinical Pharmacology &Therapeutics, Volume 119, Issue 4, Page 1047-1056, April 2026.
Baloxavir acid (baloxavir), the active metabolite of the prodrug baloxavir marboxil, is a selective inhibitor of the influenza virus cap‐dependent endonuclease. The population pharmacokinetic (popPK) profile of baloxavir in adults/adolescents has been described previously.
Sylvie Retout, Stefan De Buck, Jacques Gaudreault, Sébastien Jolivet, Vincent Duval, Valérie Cosson, Marie‐Laure Delporte   +6 more
wiley   +1 more source

An Actively Homing Insertion Element in a Phage Methylase Contains a Hidden HNH Endonuclease. [PDF]

Genes (Basel)
Arsenault D, Gosselin SP, Gogarten JP.
europepmc   +1 more source

CRISPR/Cas Genome Editing and Its Applications in Cereal Crop Improvement

Plant-Environment Interactions, Volume 7, Issue 2, April 2026.
ABSTRACT CRISPR/Cas‐based genome editing has emerged as a transformative tool for precise genetic improvement of cereal crops. Recent advances in CRISPR technologies, including Cas9, Cas12, Cas13, base editing, and prime editing, have enabled targeted modification of genes and regulatory elements controlling yield, stress tolerance, and grain ...
Sirisha Kaniganti, Himanshu Saini, A. K. Chaitanya, Niranjan Hegde, Priya Shah, Nakul D. Magar, Ramesh Rijal, Jeevan Jyoti Kaushik, Deepak Nanda, Sharad Sachan, Anand Kumar, Roopali Bhoite, Harsha Rayudu Jamedar   +12 more
wiley   +1 more source

XP-J, a ninth xeroderma pigmentosum complementation group, results from mutations in GTF2H4, encoding TFIIH-p52 subunit. [PDF]

J Clin Invest
Fassihi H, Mohammed S, Nakazawa Y, Fawcett H, Turner S, Palfrey J, Garrood I, Abiona A, Morley AM, Shimada M, Kato K, Lehmann AR, Ogi T.   +12 more
europepmc   +1 more source

An Epigenetic Clock for Accurate Age Prediction in Atlantic Cod Populations for Improved Fisheries Management

Molecular Ecology Resources, Volume 26, Issue 3, April 2026.
ABSTRACT Fisheries management relies on accurate stock assessments, which in turn depend on precise age information. Recent molecular tools called ‘epigenetic clocks’ harness age‐related DNA methylation changes to build accurate and precise age‐prediction models.
Dafni Anastasiadi, Yassine Kasmi, Christoph Stransky, Laura Casas, Erik Eschbach, Francesc Piferrer   +5 more
wiley   +1 more source

Complete mitochondrial genome of the fungal pathogen <i>Fusarium oxysporum</i> f. sp. <i>palmarum</i> responsible for fusarium wilt of palms. [PDF]

Microbiol Resour Announc
Ayika M-G, Chakrabarti S, Dhillon B.
europepmc   +1 more source

Assessment of High Throughput Sequencing Quality of Host DNA Enriched From Faeces: A Case From Captive Tiger

Molecular Ecology Resources, Volume 26, Issue 3, April 2026.
ABSTRACT Faeces serve as a widely used non‐invasive material in wildlife studies, from which host DNA can be enriched for high‐throughput sequencing. However, the characteristics of faecal DNA sequencing, particularly the relationship between sequencing volume and genotyping accuracy or genomic coverage, have remained unclear.
Jincheng Yang, Le Zhang, Liangyu Cui, Haitao Xu, Yue Ma, Lulu Liu, Mengjia Yu, Elizabeth Kamili Mtui, Xiaotong Ren, Jianing Chu, Ao Zou, Dan Liu, Lifeng Zhang, Huixin Li, Yanchun Xu, Shuhui Yang   +15 more
wiley   +1 more source

Stoichiometry-induced differential selection on codon optimization among ribosomal protein genes in bacterial species. [PDF]

Mol Biol Evol
Xia X.
europepmc   +1 more source