Results 171 to 180 of about 155,310 (382)

Simplified method for typing herpes simplex virus by restriction endonuclease analysis [PDF]

, 1983
Max Q. Arens, Ella M. Swierkosz
openalex   +1 more source

Exome Sequencing Identifies Variants in MLH1 and ERBB2 as Potential Cancer‐Predisposing Factors in Familial Early‐Onset Colorectal Cancer

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Colorectal cancer (CRC) has raised considerable health concerns worldwide, with increasing incidence rates, specifically among younger populations. Despite remarkable progress in diagnosing and treating various diseases, the genetic basis of CRC remains only partially understood.
Behnaz Bagheri, Neda Mohsen‐Pour, Najmeh Salehi, Pardis Ketabi Moghadam, Adel Zeinalpour, Amir Sadeghi, Samira Kalayinia, Nayeralsadat Fatemi   +7 more
wiley   +1 more source

Phylogenetic diversity of Moroccan cork oak woodlands fungi : mythe ou réalité ? [PDF]

, 2009
La variabilité interspécifique de 87 carpophores des champignons appartenant à 15 genres et 39 espèces ont été évaluées par l'analyse du polymorphisme de longueur de fragments de restriction (RFLP) de l'espaceur interne transcrit (ITS).
Abourouh, Mohamed, Bakkali-Yakhlef, Salahedine, Ducousso, Marc, Duponnois, Robin, Kerdouh, Benaissa, Mousain, Daniel   +5 more
core  

Relationship between laboratory mice and the subspecies Mus musculus domesticus based on restriction endonuclease cleavage patterns of mitochondrial DNA.

, 1980
Hiromichi Yonekawa, Kazuo Moriwaki, Osamu Gotoh, Junko Watanabe, Jun‐Ichi Hayashi, Nobumoto Miyashita, Michel L. Petras, Yusaku Tagashira   +7 more
openalex   +2 more sources

Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation

Science, 2014
M. Jinek, Fuguo Jiang, David W. Taylor, S. H. Sternberg, Emine Kaya, E. Ma, C. Anders, Michael Hauer, Kaihong Zhou, Steven Lin, Matias Kaplan, A. Iavarone, E. Charpentier, E. Nogales, J. Doudna   +14 more
semanticscholar   +1 more source

CRISPR Enabled Precision Oncology: From Gene Editing to Tumor Microenvironment Remodeling

Med Research, EarlyView.
CRISPR technology has progressed from a prokaryotic immune system to a diverse suite of editing platforms, including Cas nucleases, base and prime editors, and RNA‐targeting enzymes. These advances enable precise genomic and epigenomic interventions, high‐throughput functional screening, and immune engineering.
Kailai Li, Peixin Huang, Yue Qian, Anqi Lin, Jingjun He, Junyi Shen, Li Chen, Kai Miao, Jian Zhang   +8 more
wiley   +1 more source

Improving adenine base editing precision by enlarging the recognition domain of CRISPR-Cas9

Nature Communications
Domain expansion contributes to diversification of RNA-guided-endonucleases including Cas9. However, it remains unclear how REC domain expansion could benefit Cas9.
Shuliang Gao, Benson Weng, Douglas Wich, Liam Power, Mengting Chen, Huiwen Guan, Zhongfeng Ye, Chutian Xu, Qiaobing Xu   +8 more
doaj   +1 more source

Erratum: Genome-wide analysis reveals specificities of Cpf1 endonucleases in human cells

Nature Biotechnology, 2016
Daesik Kim, Jungeun Kim, J. Hur, K. W. Been, Sun-heui Yoon, Jin-Soo Kim   +5 more
semanticscholar   +1 more source

Nuclear Alpha‐Synuclein: Mechanisms and Implications for Synucleinopathies

Movement Disorders, EarlyView.
Abstract Alpha‐synuclein (aSyn), historically studied for its synaptic functions and central role in Lewy body pathology, is emerging as a protein with significant nuclear activities relevant to Parkinson's disease (PD) and related synucleinopathies. Recent advances reveal that aSyn dynamically localizes to neuronal nuclei in both health and disease ...
Tiago Fleming Outeiro, David J. Koss
wiley   +1 more source

Sequence-specific DNA Recognition by the SmaI Endonuclease [PDF]

, 1995
Barbara E. Withers, Joan C. Dunbar
openalex   +1 more source