Results 231 to 240 of about 155,310 (382)

Gene therapy for epilepsy: An emerging, promising approach for a serious neurological disorder

Journal of Internal Medicine, EarlyView.
Abstract Gene therapy is emerging as a groundbreaking strategy for treating epilepsy, offering new hope to patients who do not respond to conventional medications. Despite advancements in anti‐seizure treatments, nearly 30%–40% of individuals with epilepsy continue to experience uncontrolled seizures, highlighting the urgent need for more effective and
Marco Ledri, Merab Kokaia
wiley   +1 more source

Comprehensive genome analysis uncovers the diversity of jumbo phages in the pig gut microbiome. [PDF]

Front Vet Sci
Wei C, Chen Z.
europepmc   +1 more source

Protein-Structure Assisted Optimization of 4,5-Dihydroxypyrimidine-6-Carboxamide Inhibitors of Influenza Virus Endonuclease [PDF]

, 2017
Diane Beylkin, Gyanendra Kumar, Wei Zhou, Jae Won Park, Trushar Jeevan, Chandraiah Lagisetti, Rhodri Harfoot, Richard J. Webby, Stephen W. White, Thomas R. Webb   +9 more
openalex   +1 more source

Bacillus subtilis RNase HII Is Inefficient at Processing Guanosine Monophosphate and Damaged Ribonucleotides

Molecular Microbiology, EarlyView.
Bacillus subtilis RNase HII corrects ribonucleotide errors and mismatched ribonucleotides, but not damaged ribonucleotides. Mismatched ribonucleotides would also serve as substrates for mismatch repair while damaged ribonucleotides would be addressed through base excision repair.
Julianna R. Cresti, Lyle A. Simmons
wiley   +1 more source

Functions and applications of enzymes in nucleic acid nanotechnology. [PDF]

J Nanobiotechnology
Rong Q, Chu Z, Xu Y, Ma L, Wang L, Wang S, Yin Z, Su X.   +7 more
europepmc   +1 more source

Cleavage sites of restriction endonucleases EcoRI, BamHI and HindIII on chicken embryo rDNA [PDF]

, 1979
Walter Knöchel, Christiane Vogelsberg, Ernst-Friedrich Brost   +2 more
openalex   +1 more source

Defense Systems and Prophage Detection in Streptococcus mutans Strains

Molecular Oral Microbiology, EarlyView.
ABSTRACT Although the species is extensively studied, limited data are available on antiphage defense systems (APDSs) in Streptococcus mutans. The present study aimed to explore the diversity and the occurrence of APDSs and to search for prophages in the genomes of clinical isolates of S. mutans using bioinformatics tools.
Olivier Claisse, Cas Mosterd, Claire Le Marrec, Johan Samot   +3 more
wiley   +1 more source

Recent advances in site-specific transgene insertion into the maize genome using recombinases and genome editing endonucleases. [PDF]

Front Plant Sci
Basso MF, Pinto MS, Nonato JVA, Dante RA, Yassitepe JECT.   +4 more
europepmc   +1 more source

An Endonuclease Associated with Bovine Plasma Albumin Fraction

, 1972
Motoaki Anai, Hiroyuki Haraguchi, Yasuyuki Takagi   +2 more
openalex   +1 more source

Reconstitution of the Human tRNA Splicing Endonuclease Complex: insight into the regulation of pre-tRNA cleavage [PDF]

, 2019
Cassandra K. Hayne, Casey A. Schmidt, A. Gregory Matera, Robin E. Stanley   +3 more
openalex   +1 more source