Complete genome sequences of <i>Rhodococcus equi</i> phages CoffeeBean, Dorin, Francesca, Madraxi, and Tonitrus. [PDF]
Daspit OR+24 more
europepmc +1 more source
Summary Saintpaulia (African violet) pigmentation is notoriously unstable and sometimes forms white stripes, particularly following passage through tissue culture. White‐striped petals were thought to be due to periclinal chimeras, but we confirmed that white stripes result from epigenetic regulation rather than periclinal chimeras based on the flower ...
Daichi Kurata+5 more
wiley +1 more source
Allogeneic CART progress: platforms, current progress and limitations. [PDF]
Shokati A+5 more
europepmc +1 more source
COmapper: high‐resolution mapping of meiotic crossovers by long‐read sequencing in Arabidopsis
Summary Meiotic crossovers rearrange existing genetic variation between homologous chromosomes, profoundly affecting genomic diversity. Crossovers are typically constrained to one to three events per chromosome pair, and their distribution is shaped by chromatin accessibility and DNA polymorphisms.
Dohwan Byun+13 more
wiley +1 more source
Identification and Characterization of an R-M System in Paracoccus denitrifican DYTN-1 to Improve the Plasmid Conjugation Transfer Efficiency. [PDF]
Shi Y+6 more
europepmc +1 more source
Aggregation of the Constitutively Active K296E Rhodopsin Mutant Contributes to Retinal Degeneration
The K296E rhodopsin mutation causes autosomal dominant retinitis pigmentosa. The pathogenic effect of the mutation has typically been attributed to effects related to the constitutive activity detected in the mutant in some studies. We demonstrate here that the K296E rhodopsin mutant aggregates.
Sreelakshmi Vasudevan+2 more
wiley +1 more source
TORC2 inhibition triggers yeast chromosome fragmentation through misregulated Base Excision Repair of clustered oxidation events. [PDF]
Shimada K+9 more
europepmc +1 more source
ABSTRACT Rationale Oligonucleotides have emerged as an important new class of therapeutic. Due to their structural complexity, this presents significant challenges for the development of analytical methods to characterise and determine their impurity profile.
Mollie A. Glenister+4 more
wiley +1 more source
Development of Efficient Expression Systems for Bacteriolytic Proteases L1 and L5 of <i>Lysobacter capsici</i> XL1. [PDF]
Kudryakova I+3 more
europepmc +1 more source
We obtained potential bacterial laccase‐like multicopper oxidase (LMCO) sequences through metagenomic sequencing. All sequences exhibited significant differences from known LMCOs in databases. To select the most promising candidates, we performed structure prediction and molecular docking using alphafold2, metal3d and rosetta.
Ting Cui+5 more
wiley +1 more source