Results 131 to 140 of about 82,787 (343)

An Ultrasensitive Gold Nanoparticle-based Lateral Flow Test for the Detection of Active Botulinum Neurotoxin Type A

Nanoscale Research Letters, 2017
Botulism is a severe and potentially lethal paralytic disease caused by several botulinum neurotoxin-producing Clostridia spp. In China, the majority of the cases caused by botulism were from less-developed rural areas.
Jing Liu, Shan Gao, Lin Kang, Bin Ji, Wenwen Xin, Jingjing Kang, Ping Li, Jie Gao, Hanbin Wang, Jinglin Wang, Hao Yang   +10 more
doaj   +1 more source

Clinical relevance of Neutral Endopeptidase (NEP/CD10) in melanoma

Journal of Translational Medicine, 2007
Background Overexpression of Neutral Endopeptidase (NEP) has been reported in metastatic carcinomas, implicating NEP in tumor progression and suggesting a role for NEP inhibitors in its treatment.
Zhou Xi, Christos Paul J, Spira Joanna, Yu Yi-Lo, O'Neill David, Bogunovic Dusan, Shapiro Richard, Berman Russell, Pavlick Anna, Yancovitz Molly, Velazquez Elsa F, Mazumdar Madhu, Nanus David M, Liebes Leonard, Bhardwaj Nina, Polsky David, Osman Iman   +16 more
doaj   +1 more source

Bacillus subtilis CwlP of the SP-β Prophage Has Two Novel Peptidoglycan Hydrolase Domains, Muramidase and Cross-linkage Digesting dd-Endopeptidase*

Journal of Biological Chemistry, 2010
For bacteria and bacteriophages, cell wall digestion by hydrolases is a very important event. We investigated one of the proteins involved in cell wall digestion, the yomI gene product (renamed CwlP).
P. Sudiarta, T. Fukushima, J. Sekiguchi
semanticscholar   +1 more source

Investigation of the Urinary Peptidome to Unravel Collagen Degradation in Health and Kidney Disease

PROTEOMICS, EarlyView.
ABSTRACT Naturally occurring fragments of collagen type I alpha 1 chain (COL1A1) have been previously associated with chronic kidney disease (CKD), with some fragments showing positive and others negative associations. Using urinary peptidome data from healthy individuals (n = 1131) and CKD patients (n = 5585) this aspect was investigated in detail ...
Ioanna K. Mina, Luis F. Iglesias‐Martinez, Matthias Ley, Lucas Fillinger, Paul Perco, Justyna Siwy, Harald Mischak, Vera Jankowski   +7 more
wiley   +1 more source

Peptide Cross-Links in Bacterial Cell Wall Peptidoglycans Studied with Specific Endopeptidases from Streptomyces albus G [PDF]

, 1966
Jean‐François Petit, Emilio Muñoz, Jean‐Marie Ghuysen   +2 more
openalex   +1 more source

Cloning, Isolation, and Characterization of Mammalian Legumain, an Asparaginyl Endopeptidase*

Journal of Biological Chemistry, 1997
Legumain is a cysteine endopeptidase that shows strict specificity for hydrolysis of asparaginyl bonds. The enzyme belongs to peptidase family C13, and is thus unrelated to the better known cysteine peptidases of the papain family, C1 (Rawlings, N.
J. M. Chen, P. M. Dando, N. Rawlings, M. Brown, N. Young, R. Stevens, E. Hewitt, C. Watts, A. Barrett   +8 more
semanticscholar   +1 more source

Plasma Proteomic Signature as a Predictor of Age Advancement in People Living With HIV

Aging Cell, EarlyView.
We developed a prediction model of biological age based on 77 plasma proteins that were associated with chronological age in two independent cohorts of PLHIV and one cohort of people without HIV. PLHIV exhibited an increased age advancement that was positively associated with previous co‐infections and non‐AIDS‐related comorbidities, a higher ...
Adriana Navas, Vasiliki Matzaraki, Louise E. van Eekeren, Marc J. T. Blaauw, Albert L. Groenendijk, Wilhelm A. J. W. Vos, Maartje Jacobs‐Cleophas, Jéssica C. dos Santos, André J. A. M. van der Ven, Leo A. B. Joosten, Mihai G. Netea   +10 more
wiley   +1 more source

Lysostaphin endopeptidase-catalysed transpeptidation reactions of the imino-transfer type [PDF]

, 1977
Gary L. Sloan, Edward C. Smith, James Lancaster   +2 more
openalex   +1 more source

IgG-cleaving endopeptidase enables in vivo gene therapy in the presence of anti-AAV neutralizing antibodies

Nature Network Boston, 2020
C. Leborgne, Elena Barbon, Jeffrey M. Alexander, H. Hanby, S. Delignat, D. Cohen, F. Collaud, Saghana Muraleetharan, Dan Lupo, Joseph Silverberg, Karen Huang, Laetitia van Wittengerghe, Béatrice Marolleau, Adeline Miranda, Anna Fabiano, Victoria Daventure, Heena Beck, X. Anguela, G. Ronzitti, S. Armour, S. Lacroix-Desmazes, F. Mingozzi   +21 more
semanticscholar   +1 more source

LysK CHAP endopeptidase domain is required for lysis of live staphylococcal cells.

FEMS Microbiology Letters, 2009
LysK is a staphylococcal bacteriophage endolysin composed of three domains: an N-terminal cysteine, histidine-dependent amidohydrolases/peptidases (CHAP) endopeptidase domain, a midprotein amidase 2 domain, and a C-terminal SH3b_5 (SH3b) cell wall ...
S. C. Becker, S. Dong, J. Baker, J. Foster-Frey, D. Pritchard, D. Donovan   +5 more
semanticscholar   +1 more source