Healthy Aging Metabolomic and Proteomic Signatures Across Multiple Physiological Compartments
Aging Cell, EarlyView.The association of the aging scores with the clinical covariates suggests increased inflammation, strong predisposition to iron deficiency anemia, decline in muscle mass, and renal and hepatic functions with accelerated aging. ABSTRACT The study of biomarkers in biofluids and tissues expanded our understanding of the biological processes that drive ...
R. Moaddel +17 more
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In Vitro Stability and Inactivation of Peptide Hydrolases Extracted from Phaseolus vulgaris L [PDF]
, 2017 Endopeptidase activity against azocasein had a higher temperature optimum (50°C) in leaf extracts than in cotyledon extracts (37°C). The temperature optima for aminopeptidase (46°C) and for carboxypeptidase (53°C) were similar in leaf and cotyledon ...
Feller, Urs
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Purification and Characterization of Vicilin Peptidohydrolase, the Major Endopeptidase in the Cotyledons of Mung‐Bean Seedlings [PDF]
, 1977 Bruno Baumgartner, Maarten J. Chrispeels
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British Journal of Pharmacology, EarlyView.Immune checkpoint inhibitors (ICIs) have been a breakthrough in cancer therapy, inducing durable remissions in responding patients. However, they are associated with variable outcomes, spanning from disease hyperprogression to complete responses with the onset of immune‐related adverse events.
Mikhaël Attias, Ciriaco A. Piccirillo
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Relationship between lysostaphin endopeptidase production and cell wall composition in Staphylococcus staphylolyticus [PDF]
, 1979 John M. Robinson +2 more
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Peptidomics of prolyl endopeptidase in the central nervous system.
Biochemistry, 2009 Prolyl endopeptidase (Prep) is a member of the prolyl peptidase family and is of interest because of its unique biochemistry and connections to cognitive function.
Whitney Nolte +3 more
semanticscholar +1 more source
Diabetes, Obesity and Metabolism, EarlyView.Abstract Heart failure (HF) is a major health problem, and preventing the onset of heart failure could have large cost implications for healthcare systems globally. Screening for heart failure and its precursor, left ventricular dysfunction, could allow patients to receive therapies shown to reduce the risk of incident heart failure, such as ACE ...
Pardeep S. Jhund
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Brush border digestion : development of a physiologically relevant in vitro model : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Physiology at Massey University, Manawatū, New Zealand [PDF]
, 2018 Chapter Two has, in part, been published in the Springer publication, Reviews of Physiology, Biochemistry and Pharmacology, but the Author retains the right to publish the material in any collection consisting of the Author's own works: Hooton, D ...
Hooton, Diane Frances
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Metabolomic and proteomic stratification of equine osteoarthritis
Equine Veterinary Journal, EarlyView.Abstract Background Equine osteoarthritis (OA) is predominantly diagnosed through clinical examination and radiography, leading to detection only after significant joint pathology. The pathogenesis of OA remains unclear and while many medications modify the disease's inflammatory components, no curative or reversal treatments exist.
James R. Anderson +5 more
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Substance P and [Leu]enkephalin are hydrolyzed by an enzyme in pig caudate synaptic membranes that is identical with the endopeptidase of kidney microvilli. [PDF]
, 1983 Rebecca Matsas +3 more
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