Results 131 to 140 of about 154,667 (281)

Proteomic Characterization of Grade II Furcation Defects: A Discovery‐Phase Study

Journal of Periodontal Research, EarlyView.
This study analyzed the gingival crevicular fluid (GCF) proteome of 35 patients with Grade II furcation defects using the Olink Reveal platform. Comparison with non‐periodontitis sites identified 227 differentially expressed proteins. A machine‐learning pipeline prioritized a 34‐protein signature (including GLIPR1, MME, and IRAG2) that accurately ...
Georgios S. Chatzopoulos, Dimitra Sakellari, Eleftherios G. Kaklamanos, Lazaros Tsalikis   +3 more
wiley   +1 more source

Heterologous expression and characterization of recombinant Lactococcus lactis neutral endopeptidase (Neprilysin)

, 1996
A neutral endopeptidase (NEP) from Lactococcus lactis has recently been cloned and shown to contain high sequence homology with the human neutral endopeptidase, endopeptidase 24.11 (I. Mierau et al., J. Bacteriol. 175, 2087-2096, 1993).
Mierau, I, Lian, W, Konings, W.N, Wu, D, Hersh, L.B   +4 more
core   +1 more source

Oral Mucositis in Oncopediatric Patients: MTX and MMP‐1, MMP‐8, MMP‐13 Gene Polymorphisms

Oral Diseases, EarlyView.
ABSTRACT Background This study investigates the association between single‐nucleotide polymorphisms (SNPs) in the MMP‐1, MMP‐8, and MMP‐13 genes and the risk of oral mucositis development in paediatric patients with leukaemia and lymphoma who are undergoing methotrexate (MTX) treatment.
Nicole Januário Ribeiro, Larissa Helena Tissi, Mateus Tissot Escobar, Ana Maria Gondim Valença, Ricardo Lehtonen Rodrigues Souza, Naila Francis Paulo de Oliveira, Maria Cristina Leme Godoy Santos   +6 more
wiley   +1 more source

Proximity‐Induced Transfer of a Mass Tag Enables Direct Profiling of Active Matrix Metalloproteases

Angewandte Chemie, Volume 138, Issue 24, 8 June 2026.
A proximity‐induced, mass‐encoded activity‐based protein profiling (ABPP) approach transfers a MALDI‐detectable α‐cyano‐4‐hydroxycinnamic acid (CHCA) tag directly to active proteases. This tag enables the direct, multiplexed, and quantitative detection of enzyme activity in complex proteomes without enrichment or purification.
Lomane Berthy, Ugo Pasco, Mylene Sejalon‐Cipolla, Pierrick Bruyat, Monika Kaminska, Carole Malgorn, Fabrice Beau, Manca Osolin, Metka Novak, Barbara Breznik, Dimitris Georgiadis, Isabelle Correia, Emeline Groult, Olivier Lequin, Sarah Bregant, Yves‐Marie Pers, Daniele Noel, Robert Thai, Gilles Subra, Sonia Cantel, Laurent Devel   +20 more
wiley   +2 more sources

Distinct Properties of Neuronal and Astrocytic Endopeptidase 3.4.24.16: A Study on Differentiation, Subcellular Distribution, and Secretion Processes

, 1996
Endopeptidase 3.4.24.16 belongs to the zinc-containing metalloprotease family and likely participates in the physiological inactivation of neurotensin.The peptidase displays distinct features in pure primary cultured neurons and astrocytes.
Jean-Pierre Vincent, Bruno Vincent, Pascale Dauch, Alain Beaudet, Frédéric Checler   +4 more
core   +1 more source

Porphyromonas gingivalis GroEL accelerates abdominal aortic aneurysm formation by matrix metalloproteinase‐2 SUMOylation in vascular smooth muscle cells: A novel finding for the activation of MMP‐2

Molecular Oral Microbiology, EarlyView.
Abstract Infection is a known cause of abdominal aortic aneurysm (AAA), and matrix metalloproteases‐2 (MMP‐2) secreted by vascular smooth muscle cells (SMCs) plays a key role in the structural disruption of the middle layer of the arteries during AAA progression.
Yi‐Wen Lin, Feng‐Yen Lin, Ze‐Hao Lai, Chien‐Sung Tsai, Yi‐Ting Tsai, Yen‐Sung Huang, Chen‐Wei Liu   +6 more
wiley   +1 more source

A Boophilus microplus vitellin-degrading cysteine endopeptidase [PDF]

, 2003
Here we describe the purification and characterization of a vitellin (VT) degrading cysteine endopeptidase (VTDCE) from eggs of the hard tick Boophilus microplus.
Masuda, Aoi, Horn, Fabiana, Seixas, Adriana, Velloso, Fernando F., Termignoni, Carlos, Santos, Patricia Coutinho dos, Vaz Junior, Itabajara da Silva   +6 more
core  

An endopeptidase in dormant lupin seeds

, 1992
A new endopeptidase has been identified and partially purified from the albumin extract of dormant white lupin seeds. The enzyme is specific for the acid polypeptides of the subunits of the lupin legumin-like proteins; it acts on those present in the ...
p. cerletti, a. scarafoni, d. Giani
core   +1 more source

Glucocorticoids induce neutral endopeptidase in transformed human tracheal epithelial cells

, 1991
Neutral endopeptidase (NEP, also known as enkephalinase, CALLA, or EC 3.4.24.11) is a membrane-bound peptidase present in many different cell types. Previous studies have shown that it modulates the actions of a variety of biologically active peptides ...
D. B. Borson, D. C. Gruenert
core   +1 more source

Genetic risk variants implicate impaired maintenance and repair of periodontal tissues as causal for periodontitis—A synthesis of recent findings

Periodontology 2000, EarlyView.
AbstractPeriodontitis is a complex inflammatory disease in which the host genome, in conjunction with extrinsic factors, determines susceptibility and progression. Genetic predisposition is the strongest risk factor in the first decades of life. As people age, chronic exposure to the periodontal microbiome puts a strain on the proper maintenance of ...
Arne S. Schaefer, Luigi Nibali, Noha Zoheir, Niki M. Moutsopoulos, Bruno G. Loos   +4 more
wiley   +1 more source