Results 11 to 20 of about 177,764 (316)
Toxins, 2021 The safe and effective dosing of botulinum neurotoxins (BoNTs) requires accurate and reliable methods to measure their potency. Several novel methods have been introduced over the past decade; however, only few studies have compared the potency of BoNT ...
Ji-Yeon Hong +4 more
doaj +1 more source
Characterization of LysBC17, a Lytic Endopeptidase from Bacillus cereus
Antibiotics, 2019 Bacillus cereus, a Gram-positive bacterium, is an agent of food poisoning. B. cereus is closely related to Bacillus anthracis, a deadly pathogen for humans, and Bacillus thuringenesis, an insect pathogen.
Steven M. Swift +6 more
doaj +1 more source
Frontiers in Microbiology, 2018 Proteins constitute a particularly bioavailable subset of organic carbon and nitrogen in aquatic environments but must be hydrolyzed by extracellular enzymes prior to being metabolized by microorganisms.
Lauren Mullen +8 more
doaj +1 more source
Changes in protein profile during coagulation of latex from Carica papaya
Brazilian Journal of Medical and Biological Research, 1997 We describe the changes in peptide composition by SDS-PAGE analysis of latex from Carica papaya collected at various times after incision of the unripe fruit.
L.G. Silva +3 more
doaj +1 more source
Genetic Evidence for Distinct Functions of Peptidoglycan Endopeptidases in Escherichia coli
Frontiers in Microbiology, 2020 Peptidoglycan (PG) is an essential component of the bacterial exoskeleton that plays a pivotal role in the maintenance of cell shape and resistance to cell lysis under high turgor pressures.
Si Hyoung Park +4 more
doaj +1 more source
Frontiers in Cell and Developmental Biology, 2022 Small ubiquitin-like modifier (SUMO) modification plays an important regulatory role in T cell receptor (TCR) signaling transduction. SUMO-specific proteases (SENPs) have dual-enzyme activities; they can both process SUMO precursors as endopeptidases and
Yun-Yi Li +6 more
doaj +1 more source
Role of the liver in splanchnic extraction of atrial natriuretic factor in the rat [PDF]
, 1992 Mesenteric, hepatic and splanchnic extraction of C-terminal and N-terminal atrial natriuretic factor was investigated in male Sprague-Dawley rats. Plasma concentrations (mean ± S.E.M.) of C-terminal atrial natriuretic factor were 55.0 ± 6.1 fmol/ml, 31.2
Alexander L. Gerbes +39 more
core +1 more source
Computer-aided lead optimization: improved small-molecule inhibitor of the zinc endopeptidase of botulinum neurotoxin serotype A. [PDF]
PLoS ONE, 2007 Optimization of a serotype-selective, small-molecule inhibitor of botulinum neurotoxin serotype A (BoNTA) endopeptidase is a formidable challenge because the enzyme-substrate interface is unusually large and the endopeptidase itself is a large, zinc ...
Jing Tang +4 more
doaj +1 more source
Serum neprilysin levels are elevated in preeclampsia
Taiwanese Journal of Obstetrics & Gynecology, 2021 Objective: To evaluate the possible associations between serum Neprilysin (NEP) levels and preeclampsia and mild and severe preeclampsia subgroups. Materials and methods: Fifty-five consecutive women with mild preeclampsia and fifty-five consecutive ...
Nevin Tüten +8 more
doaj +1 more source
Sonic Hedgehog Is a Member of the Hh/DD-Peptidase Family That Spans the Eukaryotic and Bacterial Domains of Life. [PDF]
, 2018 Sonic Hedgehog (Shh) coordinates Zn2+ in a manner that resembles that of peptidases. The ability of Shh to undergo autoproteolytic processing is impaired in mutants that affect the Zn2+ coordination, while mutating residues essential for catalytic ...
Roelink, Henk
core +3 more sources