Results 121 to 130 of about 636,928 (251)
Cell cycle-dependent regulation of structure of endoplasmic reticulum and inositol 1,4,5-trisphosphate-induced Ca2+ release in mouse oocytes and embryos [PDF]
, 2003 The organization of endoplasmic reticulum (ER) was examined in mouse eggs undergoing fertilization and in embryos during the first cell cycle. The ER in meiosis 11 (MII)-arrested mouse eggs is characterized by accumulations (clusters) that are restricted
Carroll, J, Marangos, P, FitzHarris, G
core
Marine Drugs, 2016 Doxorubicin (DOX) is a highly potent chemotherapeutic agent, but its usage is limited by dose-dependent cardiotoxicity. DOX-induced cardiotoxicity involves increased oxidative stress and activated endoplasmic reticulum-mediated apoptosis.
Jun-Jie Guo +8 more
doaj +1 more source
Endoplasmic reticulum stress and liver diseases
Liver Research, 2019 Endoplasmic reticulum (ER) stress occurs when ER homeostasis is perturbed with accumulation of unfolded/misfolded protein or calcium depletion. The unfolded protein response (UPR), comprising of inositol-requiring enzyme 1α (IRE1α), PKR-like ER kinase ...
Xiao-Ying Liu, R. Green
semanticscholar +1 more source
Phosphatidylinositol synthesis at the endoplasmic reticulum.
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, 2019 Phosphatidylinositol (PI) is a minor phospholipid with a characteristic fatty acid profile; it is highly enriched in stearic acid at the sn-1 position and arachidonic acid at the sn-2 position.
Nicholas J. Blunsom, S. Cockcroft
semanticscholar +1 more source
Dissection of the asynchronous transport of intestinal microvillar hydrolases to the cell surface [PDF]
, 1988 Novel subcellular fractionation procedures and pulse-chase techniques were used to study the intracellular transport of the microvillar membrane hydrolases sucrase-isomaltase and dipeptidylpeptidase IV in the differentiated colon adenocarcinoma cell line
B Stieger +11 more
core +1 more source
Endocrine Regulations, 2019 Objective. The aim of the present study was to examine the effect of glucose deprivation on the expression of genes encoded glucocorticoid receptor (NR3C1) and some related proteins (NR3C2, AHR, NRIP1, NNT, ARHGAP35, SGK1, and SGK3) in U87 glioma cells ...
Riabovol Olena O. +6 more
doaj +1 more source
Endoplasmic reticulum storage diseases
Swiss Medical Weekly, 2002 The endoplasmic reticulum represents the cell's quality control site for accurate folding of secretory and membrane proteins. Quality control is achieved through the association of ER chaperones with unfolded or misfolded polypeptide chains. In the ER stress response, upregulation of chaperones occurs as a consequence of misfolded proteins accumulating
Rutishauser, J., Spiess, M.
openaire +3 more sources
Glycosylation can influence topogenesis of membrane proteins and reveals dynamic reorientation of nascent polypeptides within the translocon [PDF]
, 1999 The topology of multispanning membrane proteins in the mammalian endoplasmic reticulum is thought to be dictated primarily by the first hydrophobic sequence.
Martin Spiess +5 more
core +1 more source
Cellular Physiology and Biochemistry, 2016 Background/Aims: Melatonin, which is mainly secreted by the pineal gland and released into blood, has anti-inflammatory properties in acute pancreatitis. Many studies show that melatonin can relieve inflammation in taurocholate-induced acute pancreatitis.
Yina Chen +6 more
doaj +1 more source
Introductory Chapter: Endoplasmic ReticulumKnowledge and Perspectives [PDF]
, 2019 The endoplasmic reticulum is one of the most studied and fascinating organelles. It is found in all eukaryotic cells and performs a variety of functions.
Catala, Angel, Angel Catala
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