Results 271 to 280 of about 755,597 (345)

Secreted Nonstructural Protein 3 is a Pathogenic Determinant of Orbivirus

Advanced Science, EarlyView.
This study uncovers a conserved PIP2‐dependent secretory pathway of orbivirus NS3 that induces vascular leakage. Pharmacological disruption of PIP2‐NS3 interaction significantly reduces viral pathogenicity and provides protective efficacy in murine models, establishing PIP2‐mediated NS3 secretion as both a key virulence determinant and a promising ...
Junyong Guan, Dong Zhou, Ran Shao, Xing Liu, Jin Peng, Yingran Huang, Shuhui Qi, Cankun Xi, Menghang Wang, Bin Sun, Yinglin Qi, Xin Yin   +11 more
wiley   +1 more source

DERL3 exacerbates glioblastoma malignancy through endoplasmic reticulum stress-dependent mechanisms. [PDF]

Am J Cancer Res
Du S, Zhang S, Li C, Du S, Guan S, Wang S, Wang Z, Dong T, Ren X.   +8 more
europepmc   +1 more source

Sensing and Filtering Environmental Fluctuations: The Case of Biomolecular Condensates in Plants

Advanced Science, EarlyView.
The diversity of plant condensates reflects constraints of sessile organisms to coordinate postembryonic development with environmental adaptation. This review examines how plants employ condensates to integrate temperature, light, redox, and nutrient signals.
Panagiotis N. Moschou, Dorothee Staiger
wiley   +1 more source

Role of abnormal phosphatidylcholine metabolism in endoplasmic reticulum stress-induced carotid artery plaque destabilization. [PDF]

Atheroscler Plus
Hu Q, Zhang H, Wang X, Huang J, Jiang X, Li M, Chen D.   +6 more
europepmc   +1 more source

Dumbbell‐Structured Plasmonic‐Enhanced Optical Nanoprobes Boosting Photo‐Magnetic‐Acoustic Multimodal Imaging‐Guided Photodynamic‐Photothermal Synergistic Treatment and Immunogenic Death in Nasopharyngeal Carcinoma

Advanced Science, EarlyView.
This study reports a novel rationally‐designed optical nanoprobe based on dumbbell‐shaped mesoporous silica‐coated gold nanorods, loaded with rare‐earth oxides, photosensitizers, and tumor‐targeted peptides, enabling plasmonic‐enhanced multimodal imaging and PTT‐PDT synergy.
Baikang Zhuang, Yubiao Yang, Wen Han, Yi Tang, Chengxin Yao, Fuli Zhao, Wenxiao Fang, Jinjie Li, Xiaolan Huo, Yiqian An, Yuanzhi Shao, Botao Gao, Jinchang Yin   +12 more
wiley   +1 more source

Endoplasmic Reticulum Stress in Cancer. [PDF]

MedComm (2020)
Zhou R, Wang W, Li B, Li Z, Huang J, Li X.   +5 more
europepmc   +1 more source

Mitochondria-Associated Endoplasmic Reticulum Membranes in Health and Diseases. [PDF]

MedComm (2020)
Hong H, Guo Z, Ge J, Li H.
europepmc   +1 more source

Identification and validation of an endoplasmic reticulum stress related model to predict prognosis and tumor microenvironment in neuroblastoma. [PDF]

BMC Cancer
Chen J, Du B, Jiang B, Huang L.
europepmc   +1 more source

The endoplasmic reticulum displays high polarity with low protein aggregation in human cells. [PDF]

Commun Biol
Hu X, Chen J, Liu P, Zhang H, Liu Y, Zhang X, Wang L.   +6 more
europepmc   +1 more source

Endoplasmic reticulum stress-mediated cell death in spinal cord injury: from molecular mechanisms to therapeutic applications. [PDF]

Front Cell Dev Biol
Zeng WC, Zeng FJ.
europepmc   +1 more source