Results 281 to 290 of about 755,597 (345)

Signal integration in the endoplasmic reticulum unfolded protein response

Nature Reviews Molecular Cell Biology, 2007
D. Ron, P. Walter
semanticscholar   +3 more sources

Calcium signaling and endoplasmic reticulum stress.

International Review of Cell and Molecular Biology, 2021
Cellular homeostasis is essential for healthy functioning of cells and tissues as well as proper organ development and maintenance. A disruption in cellular homeostasis triggers stress responses including the unfolded protein response (UPR), an ...
J. Groenendyk, L. Agellon, M. Michalak
semanticscholar   +1 more source

Endoplasmic Reticulum Stress

Annals of the New York Academy of Sciences, 2007
Abstract:  Stress is the imbalance of homeostasis, which can be sensed even at the subcellular level. The stress‐sensing capability of various organelles including the endoplasmic reticulum (ER) has been described. It has become evident that acute or prolonged ER stress plays an important role in many human diseases; especially those involving organs ...
BANHEGYI G, BAUMEISTER P, BENEDETTI A, DONG D, FU Y, LEE AS, LI J, MAO C, MARGITTAI E, NI M, PASCHEN W, PICCIRELLA S, SENESI S, SITIA , ROBERTO, WANG M, YANG W.   +15 more
openaire   +3 more sources

Endoplasmic Reticulum Targeting to Amplify Immunogenic Cell Death for Cancer Immunotherapy.

Nano letters (Print), 2020
Immunogenic cell death (ICD) elicited by photodynamic therapy (PDT) is mediated through generation of reactive oxygen species (ROS) that induce endoplasmic reticulum (ER) stress. However, the half-life of ROS is very short and the intracellular diffusion
Hongzhang Deng, Zijian Zhou, Weijing Yang, Li-sen Lin, Sheng Wang, G. Niu, Jibin Song, Xiaoyuan Chen   +7 more
semanticscholar   +1 more source

An Endoplasmic Reticulum Targeted Ratiometric Fluorescent Probe for Sensing of Hydrogen Sulfide in Living Cells and Zebrafish.

Analytical Chemistry, 2020
Hydrogen sulfide (H2S) is an endogenous gaseous signaling molecule in many physiological processes. Relevant investigations indicated that H2S plays a cytoprotective effect under endoplasmic reticulum stress.
Wei Shu, Shunping Zang, Chong Wang, Mengxu Gao, Jing Jing, Xiaoling Zhang   +5 more
semanticscholar   +1 more source

Crosstalk between Endoplasmic Reticulum stress and oxidative stress:Focus on Protein Disulfide Isomerase and Endoplasmic Reticulum Oxidase 1.

European Journal of Pharmacology, 2020
Cellular stress and inflammation, establishing as disease pathology, have reached great heights in the last few decades. Stress conditions such as hyperglycemia, hyperlipidemia and lipoproteins are known to disturb proteostasis resulting in the ...
Paul Victor, D. Sarada, K. Ramkumar
semanticscholar   +1 more source