Results 81 to 90 of about 404,308 (207)

Intracellular glutathione pools are heterogeneously concentrated [PDF]

, 2013
Glutathione is present in millimolar concentrations in the cell, but its relative distribution among cellular compartments remains elusive. We have chosen the endoplasmic reticulum (ER) as an example organelle to study compartment-specific glutathione ...
Christine Tachibana, Jakob Rahr Winther, Rahr Winther, Jakob, Winther, Jakob R., Appenzeller-Herzog, Christian, Davide Montero, Tachibana, Christine, Christian Appenzeller-Herzog, Montero, Davide   +8 more
core   +1 more source

The isolation and characterisation of temperature-dependent Ricin A chain molecules in Saccharomyces cerevisiae. [PDF]

, 2007
Ricin is a heterodimeric plant protein that is potently toxic to mammalian cells. Toxicity results from the catalytic depurination of eukaryotic ribosomes by ricin A chain (RTA) that follows toxin endocytosis to, and translocation across, the ...
Ladds, Graham, Moffat, K G, Allen, Stuart C H, Fulop, V, Moore, Katherine A. H., Marsden, Catherine J., Marsden, C J, Ladds, G, Roberts, L M, Lord, Mike, Lord, J M, Allen, Stuart C. H., Roberts, L. M. (Lynne M.), Moffat, Kevin G., Fülöp, Vilmos, Moore, K A H   +15 more
core   +1 more source

Research hotspots and frontiers of endoplasmic reticulum in glomerular podocytes: a bibliometric and visual analysis from 2005 to 2023

Frontiers in Pharmacology
BackgroundThe glomerular podocyte endoplasmic reticulum is a critical component in renal function, yet its research landscape is not fully understood.
Wang Junli, Hao Zhihong, Wang Lina, Ou Qiaoqun, Qu Jing, Hu Jiaqi, Shengyou Yu, Shengyou Yu, Shengyou Yu   +8 more
doaj   +1 more source

Targeting the calcium ATPase to the endoplasmic reticulum

, 2009
The sarco/endoplasmic reticulum calcium ATPase (SERCA) pumps calcium from thecytoplasm into the lumen of the endoplasmic or sarcoplasmic reticulum (ER/SR), removingexcess Ca2+ from the cytoplasm and replenishing ER/SR Ca2+ stores. SERCA is located inboth
Watson, Helen Rachel
core  

Glycosylation can influence topogenesis of membrane proteins and reveals dynamic reorientation of nascent polypeptides within the translocon [PDF]

, 1999
The topology of multispanning membrane proteins in the mammalian endoplasmic reticulum is thought to be dictated primarily by the first hydrophobic sequence.
Martin Spiess, Veit Goder, Goder, V., Spiess, M., Christoph Bieri, Bieri, C.   +5 more
core   +1 more source

Inhibition of cellular protein secretion by norwalk virus nonstructural protein p22 requires a mimic of an endoplasmic reticulum export signal.

, 2013
Protein trafficking between the endoplasmic reticulum (ER) and Golgi apparatus is central to cellular homeostasis. ER export signals are utilized by a subset of proteins to rapidly exit the ER by direct uptake into COPII vesicles for transport to the ...
Estes, M. K., Guix Arnau, Susana, Katayama, K., Crawford, Sue E., Sharp, T. M.   +4 more
core   +1 more source

Introductory Chapter: Endoplasmic ReticulumKnowledge and Perspectives [PDF]

, 2019
The endoplasmic reticulum is one of the most studied and fascinating organelles. It is found in all eukaryotic cells and performs a variety of functions.
Catala, Angel, Angel Catala
core   +1 more source

Syntaxin 16 and syntaxin 5 are required for efficient retrograde transport of several exogenous and endogenous cargo proteins [PDF]

, 2007
Retrograde transport allows proteins and lipids to leave the endocytic pathway to reach other intracellular compartments, such as trans-Golgi network (TGN)/Golgi membranes, the endoplasmic reticulum and, in some instances, the cytosol. Here, we have used
Falguières, Thomas, Roberts, L., Smith, Daniel C., Lord, J., Fradagrada, Alexandre, Amessou, Mohamed, Amessou, M., Johannes, Ludger, Fradagrada, A., Falguieres, T., Lord, Mike, Roberts, L. M. (Lynne M.), Lamaze, Christophe, Lamaze, C., Johannes, L., Smith, D.   +15 more
core   +1 more source

Location matters: the endoplasmic reticulum and protein trafficking in dendrites

Biological Research, 2011
Neurons are highly polarized, but the trafficking mechanisms that operate in these cells and the topological organization of their secretory organelles are still poorly understood.
Omar A Ramírez, Steffen Härtel, Andrés Couve   +2 more
doaj  

Dissection of the asynchronous transport of intestinal microvillar hydrolases to the cell surface [PDF]

, 1988
Novel subcellular fractionation procedures and pulse-chase techniques were used to study the intracellular transport of the microvillar membrane hydrolases sucrase-isomaltase and dipeptidylpeptidase IV in the differentiated colon adenocarcinoma cell line
B Stieger, K Matter, K Bucher, M Höchli, Baur, B., B Baur, Hochli, M., Bucher, K., Stieger, B., Matter, K., Hauri, H. P., H P Hauri   +11 more
core   +1 more source