Endoplasmic reticulum stress and lipids in health and diseases.
Progress in lipid research, 2022 Cenk Celik +3 more
semanticscholar +1 more source
Advancing Clinical Medicine with Raman Spectroscopy: Current Trends and Future Perspectives
Advanced Photonics Research, EarlyView.Raman spectroscopy and microscopy may become excellent tools in clinical medicine, including hematology, oncology, infectious diseases, neurology, gastroenterology, reproductive medicine, rheumatology, and cardiovascular research. However, many challenges such as signal interference, standardization issues, and limited clinical application need to be ...
Jiří Bufka +5 more
wiley +1 more source
Trehalose is required for conformational repair of heat‐denatured proteins in the yeast endoplasmic reticulum but not for maintenance of membrane traffic functions after severe heat stress [PDF]
, 2000 Mari Simola +3 more
openalex +1 more source
Innovative Fluorescent Probes to Track Lipid Droplets and Endoplasmic Reticulum Dynamics
Advanced Sensor Research, EarlyView.Eco‐designed fluorescent probes enable selective imaging of lipid droplets and endoplasmic reticulum dynamics. Through green multicomponent synthesis, the probes exhibit high photostability and distinct subcellular localization. Their targeting selectivity arises from molecular geometry and microenvironmental adaptability, offering sustainable tools ...
Diana García‐García +5 more
wiley +1 more source
The physiological role of the unfolded protein response in the nervous system
Neural Regeneration ResearchThe unfolded protein response (UPR) is a cellular stress response pathway activated when the endoplasmic reticulum, a crucial organelle for protein folding and modification, encounters an accumulation of unfolded or misfolded proteins.
Shuangchan Wu, Wensheng Lin
doaj +1 more source
Endoplasmic Reticulum Stress-induced Cysteine Protease Activation in Cortical Neurons [PDF]
, 2001 Robert Siman +3 more
openalex +1 more source
Possibilities of Inner Ear Barrier Models for Otologic Drug Development
Advanced Therapeutics, EarlyView.This review examines innovative organ chip models that reconstruct critical inner ear barriers, addressing a fundamental challenge in otologic drug development: the limited understanding of pharmaceutical behavior across these complex barriers. By replicating these barriers, the advanced models offer promising alternatives to traditional testing ...
Yeji Ahn +7 more
wiley +1 more source
Ischemia-Responsive Protein (irp94) Is Up-Regulated by Endoplasmic Reticulum Stress [PDF]
, 2001 Seung Whan Kim +3 more
openalex +1 more source
Advanced Science, EarlyView.The schematic diagram illustrates the role of the recruitment of Gal3‐CaN‐Smurf1 complex in maintaining lysosomal membrane homeostasis upon damage. On the one hand, the Gal3‐CaN‐Smurf1 complex sequesters FLCN‐FNIPs to block the activation of RagC, where the active form RagC‐GDP is responsible for TFEB phosphorylation.
Qin Xia +10 more
wiley +1 more source
Targeting of the prion protein to the cytosol: mechanisms and consequences
, 2010 Prion diseases are characterized by the conformational transition of the cellular prion protein (PrPC) into an aberrant protein conformer, designated scrapie-prion protein (PrPSc).
Miesbauer, M. +3 more
core