Results 201 to 210 of about 356,983 (328)

Tangeretin prevents cardiac failure induced by reperfusion/ischaemia by inhibiting apoptosis, endoplasmic reticulum stress, and JNK/ERK pathway [PDF]

, 2020
Yu Liu, Jian Wang, Chuanlei Zhang, Xinran Hou, Yan Kong   +4 more
openalex   +1 more source

Chloroplast Stress Signals Orchestrate Epidermis‐Specific Remodeling of Mitochondria and ER Under High Light

Advanced Science, EarlyView.
High light exposure triggers an epidermis‐specific remodeling of mitochondria and ER in Arabidopsis, driven by chloroplast‐derived signals. Live‐cell imaging shows that HL rapidly suppresses mitochondrial motility, followed by fusion‐driven elongation and ER cisternal expansion.
Evan R. Angelos, Hee‐Seung Choi, Jingzhe Guo, Andrea A. Zanini, Tessa M. Burch‐Smith, Emily Snyder, Matthew Part, Wilhelmina van de Ven, Manhoi Hur, Gerd Ulrich Balcke, Alain Tissier, Quanqing Zhang, Katayoon Dehesh   +12 more
wiley   +1 more source

Monogenic diabetes: the role of mitochondrial dysfunction and endoplasmic reticulum stress. [PDF]

Front Clin Diabetes Healthc
Ozsu E.
europepmc   +1 more source

Calcium homoeostasis modulator 1 (CALHM1) reduces the calcium content of the endoplasmic reticulum (ER) and triggers ER stress

, 2011
Sonia Gallego‐Sandín, Marı́a Teresa Alonso, Javier García‐Sancho   +2 more
openalex   +2 more sources

Targeting Microglial CD49a Inhibits Neuroinflammation and Demonstrates Therapeutic Potential for Parkinson's Disease

Advanced Science, EarlyView.
This study shows that integrin receptor CD49a (Itga1 gene) is significantly upregulated in hyperactivated microglia and microglia‐specific knockdown of Itga1 rescues neuroinflammation and neurodegeneration in a chronic Parkinson's disease (PD) model by targeting PGAM5‐mediated mitochondrial dysfunction and NLRP3 activation. Targeted inhibition of CD49a
Huanpeng Lu, Yunmin Zhu, Xi Wang, Zelin Wu, Zijian Xu, Rongqing Chen, Yanwu Guo   +6 more
wiley   +1 more source

DERL3 exacerbates glioblastoma malignancy through endoplasmic reticulum stress-dependent mechanisms. [PDF]

Am J Cancer Res
Du S, Zhang S, Li C, Du S, Guan S, Wang S, Wang Z, Dong T, Ren X.   +8 more
europepmc   +1 more source

Listeria monocytogenes induces an interferon-enhanced activation of the integrated stress response that is detrimental for resolution of infection in mice [PDF]

, 2017
Allagnat, Allen, Atkins, Auerbuch, Bettigole, Blalock, Calfon, Carrero, Carrero, Carrero, Carrero, Celada, Cho, Cullinan, Cullinan, Czuczman, Dabo, Edelson, Endo, Farrand, Ferlito, Fonseca, Gaillard, Gekara, Glomski, Grabiner, Gusella, Guzmán, Hamon, Han, Harding, Harding, Harding, Hassan, Hetz, Hiramatsu, Inaba, Ingrand, Ishibashi, Jammi, Kozutsumi, Köster, Lam, Li, Martinon, Masuoka, McCaffrey, Merquiol, Nakamura, Novoa, O'Connell, O'Riordan, Okumura, Oyadomari, Pasqual, Pavio, Peña, Portnoy, Sauer, Scheuner, Seimon, Stavru, Stockinger, Stockinger, Tabas, Tardif, Vattem, Walter, Wheeler, Woo, Yamamoto, Zinszner   +71 more
core   +2 more sources

GbWAKL20 Phosphorylates GbNFYB8 to Modulate Verticillium Wilt Resistance in Cotton

Advanced Science, EarlyView.
Wall‐associated receptor‐like kinases (WAKLs) play pivotal roles in extracellular–intracellular signal transduction. Upon sensing Verticillium dahliae infestation at the plasma membrane, GbWAKL20 accumulates and transmits signals to the nucleus via endoplasmic reticulum‐mediated Golgi vesicle transport.
Guilin Wang, Qingxin Si, Zhiguo Chen, Zhe Yu, Zhan Guo, Lu Wang, Weixi Li, Wangzhen Guo   +7 more
wiley   +1 more source

Erratum: Endoplasmic reticulum stress in non-small cell lung cancer. [PDF]

Am J Cancer Res
Li X, Hu F, Lu T, Wu S, Ma G, Lin Y, Zhang H.   +6 more
europepmc   +1 more source

Acetylation Regulates ACSL4 Degradation Through Chaperone‐Mediated Autophagy to Alleviate Intervertebral Disc Degeneration

Advanced Science, EarlyView.
Intervertebral disc degeneration is triggered by ACSL4 accumulation‐mediated ferroptosis of nucleus pulposus cells due to CMA dysfunction. KAT2B promotes ACSL4 degradation via CMA through acetylation. AAV‐mediated LAMP2A delivery or engineered exosomes rescue nucleus pulposus cell senescence and disc degeneration.
Zhouwei Wu, Zhichen Jiang, Chenglong Hong, Shu Yang, Shuqing Jin, Chenyu Wu, Kaijie Guo, Jiang Liu, Shaobo Xu, Chenggui Wang, Xiangyang Wang   +10 more
wiley   +1 more source