Results 201 to 210 of about 144,544 (285)

Effect of pH on small-molecule inhibitor binding to influenza virus hemagglutinin. [PDF]

J Biol Chem
Anirudhan V, Gaisina I, Shimon A, Lee H, Alqarni S, Manicassamy B, Moore TW, Xu K, Caffrey M, Rong L.   +9 more
europepmc   +1 more source

Bioengineered Bacterial Vesicles and Biomimetic Hybrids Eliminate Biofilms and Balance the Gut Microbiome

Small, EarlyView.
Biomimetic nanocarriers based on liposomes and Myxobacteria outer‐membrane vesicles (OMVs) are effective antibiotic delivery systems. Hybrids have a higher drug loading and can target intracellular pathogens, while OMVs evade immune clearance. Biomimetic nanoantibiotics effectively eliminate the biofilms of Gram‐negative bacteria. Besides, Myxobacteria
Leila Pourtalebi Jahromi, Benedikt Kronast, Jennifer Munkert, Lorenzo Sana, Marcus Koch, Heike Danzer, Sirka Dormeyer, Shuhan Jiang, Fabian Herrmann, Matthias Weiler, Anna Kashkanova, Vahid Sandoghdar, Mario M. Zaiss, Gregor Fuhrmann   +13 more
wiley   +1 more source

Increased Neuronal Expression of the Early Endosomal Adaptor APPL1 Replicates Alzheimer's Disease-Related Endosomal and Synaptic Dysfunction with Cholinergic Neurodegeneration. [PDF]

J Neurosci
Jiang Y, Sachdeva K, Goulbourne CN, Berg MJ, Peddy J, Stavrides PH, Pensalfini A, Pawlik M, Malampati S, Whyte L, Basavarajappa BS, Subbanna S, Bleiwas C, Smiley JF, Mathews PM, Nixon RA.   +15 more
europepmc   +1 more source

Decoding pH‐Driven Phase Transition of Lipid Nanoparticles

Small, EarlyView.
Ionizable aminolipids govern lipid nanoparticle (LNP) function through environment‐dependent protonation. Constant‐pH molecular dynamics reveal intrinsic, apparent, and surface pKa${\rm pK}_{\text{a}}$ values within LNP‐mimetic membranes, demonstrating that the LNP lipid environment induces a pronounced downward pKa${\rm pK}_{\text{a}}$ shift exceeding
Marius F.W. Trollmann, Rainer A. Böckmann   +1 more
wiley   +1 more source

Cell Trafficking Disorders Play an Important Role in the Pathogenesis of Skeletal Dysplasias. [PDF]

Turk Arch Pediatr
Tüysüz B.
europepmc   +1 more source

Endosome signaling

The Journal of Cell Biology, 2006
openaire   +2 more sources

Medical Gas Plasma Inactivates Adenoviruses via Capsid Oxidation

Small, EarlyView.
Oxidative modification of three adenoviral capsid proteins after gas plasma treatment. Schematic representation of the viral infection process, starting with the initial attachment of the virus via its fiber protein binding to the cellular receptors (CAR and/or CD46). In the secondary attachment step, the penton base binds to integrin structures on the
Anke Schmidt, Meike Heuser, Paul Schulan, Lea Miebach, Alice Martinet, Marcus Frank, Kristian Wende, Sander Bekeschus   +7 more
wiley   +1 more source

Endoplasmic reticulum junctions serve as a platform for endosome-lysosome interactions through their stop-and-go motion switching. [PDF]

Sci Adv
Li W, Guo Y, Wang Q, Qiu M, Zhang Y, Yang Y, Hu J, Yang G.   +7 more
europepmc   +1 more source

Heavy Metals in Elecronic Cigarette Aersol Can Accumulate in Lung Epithelial Cells [PDF]

, 2019
Zaman, Rafay
core  

To Dye or Not to Dye: Unraveling the Impact of Surface Chemistry on Cerium Oxide Nanoparticles–Cell Interactions

Small Science, EarlyView.
Fluorescent dye labeling enables nanoparticle imaging but may subtly alter their surface chemistry and biological behavior. This study compares dye‐labeled and unlabeled cerium oxide nanozymes, revealing changes in cellular uptake kinetics without affecting their final intracellular fate. Combined fluorescence and label‐free electron microscopy imaging
Kanika Dulta, Thu Ngan Dinhová, Marie Hubálek Kalbáčová, Xiaohui Ju   +3 more
wiley   +1 more source