Results 301 to 310 of about 138,036 (346)

Repeated ER–endosome contacts promote endosome translocation and neurite outgrowth [PDF]

open access: yesNature, 2015
The main organelles of the secretory and endocytic pathways--the endoplasmic reticulum (ER) and endosomes, respectively--are connected through contact sites whose numbers increase as endosomes mature.
C. Raiborg   +11 more
semanticscholar   +2 more sources

Recycling Endosome Membrane Incorporation into the Leading Edge Regulates Lamellipodia Formation and Macrophage Migration [PDF]

open access: yesTraffic, 2010
In comparison to our knowledge of the recycling of adhesion receptors and actin assembly, exactly how the cell controls its surface membrane to form a lamellipodium during migration is poorly understood.
Rachael Z Murray
exaly   +2 more sources
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The endosome as engineer

Science, 2022
Endosomes use lipid signaling to shape organelles according to nutrient ...
Maria Clara, Zanellati, Sarah, Cohen
openaire   +2 more sources

Endosomal and non-endosomal functions of ESCRT proteins

Trends in Cell Biology, 2006
The three endosomal sorting complexes required for transport (ESCRTs) are integral to the degradation of endocytosed membrane proteins and multivesicular body (MVB) biogenesis. Here, we review evidence that ESCRTs have evolved as a specialized machinery for the degradative sorting of ubiquitinated membrane proteins and we highlight recent studies that ...
Thomas, Slagsvold   +3 more
openaire   +2 more sources

Regulation of endosome fusion

Molecular Membrane Biology, 1999
Homotypic fusion between early endosomes can be reconstituted in vitro. By using wortmannin and LY294002, inhibitors of phosphatidylinositol (Pl) 3-kinase, a requirement for this activity has been established in order for fusion to proceed efficiently.
Ian Mills   +2 more
exaly   +3 more sources

The endosomal network

Int. Journal of Clinical Pharmacology and Therapeutics, 2009
Endocytosis is the process by which extracellular molecules are captured by the cell surface membrane and then taken up into the cell. Once inside the cell, the internalized material is delivered to its final destination via a complex system of organelles, termed the endosomal network.
openaire   +2 more sources

Endosomes, receptors, and viruses

Science, 2022
Mechanisms of infection are deciphered at the host-pathogen ...
openaire   +2 more sources

Endosomal system of Paramecium: coated pits to early endosomes

Journal of Cell Science, 1992
ABSTRACT A detailed morphological and tracer study of endocytosis via coated pits in Paramecium multimicronucleatum was undertaken to compare endocytic processes in a free-living protozoon with similar processes in higher organisms. Permanent pits at the cell surface enlarge, become coated and give rise to coated vesicles (188±41 nm in ...
R D, Allen, C C, Schroeder, A K, Fok
openaire   +2 more sources

Plant signaling endosomes and endosome trafficking

Russian Journal of Plant Physiology, 2010
A discovery of a possibility for signal transduction from endosomes differing quantitatively and qualitatively from signaling from the plasma membrane became a reliably proved fact for animal and yeast receptors but was unaddressed by plant researches for a long time.
openaire   +1 more source

Late endosomes derive from early endosomes by maturation

Cell, 1991
Endocytosed proteins destined for degradation in lysosomes are targeted mainly to early endosomes following uptake. Late endosomes are the major site for entry of newly synthesized lysosomal hydrolases via the cation-independent mannose 6-phosphate receptor into the degradative pathway. No consensus exists as to the mechanism of transport from early to
Stoorvogel, W   +4 more
openaire   +3 more sources

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