Results 291 to 300 of about 138,036 (346)

The role of iron in normal and impaired testicular function

Andrology, EarlyView.
Abstract Iron plays a critical role in testicular physiology, impacting spermatogenesis, testosterone production, and overall testicular function. Iron homeostasis is maintained through systemic and cellular regulatory mechanisms, including hepcidin‐mediated systemic iron control and the iron‐responsive element/iron regulatory protein (IRE/IRP) system ...
Aileen Harrer, Esther G. Meyron‐Holtz, Andreas Meinhardt   +2 more
wiley   +1 more source

Failure of Hepatic Insulin Clearance via CEACAM1-Mediated Endocytosis: The Missing Physiological Link Between Proinsulin Misfolding, Hyperinsulinemia, and Metabolic Complications in Type 2 Diabetes, Obesity, and NAFLD. [PDF]

Probl Endokrinol (Mosk)
Akl MM, Ahmed A.
europepmc   +1 more source

Intracellular Localization of PD-L1 in Rab10-positive Open Tubular Endosome System of Cancer Cells. [PDF]

Acta Histochem Cytochem
Yamada R, Sakamoto R, Kawai K, Egami Y, Araki N.   +4 more
europepmc   +1 more source

Huntingtin polyglutamine expansions misdirect axonal transport by perturbing motor and adaptor recruitment. [PDF]

iScience
Prowse ENP, Turkalj BA, Sébastien M, Gursu L, Beaudet D, Feng J, Zhou C, McBride HM, Brouhard GJ, Pouladi MA, Hendricks AG.   +10 more
europepmc   +1 more source

A luminescent reporter assay to quantify SORL1 ectodomain shedding and retromer-dependent endosome recycling activity. [PDF]

J Biol Chem
Fazeli E, Jan A, Huber AK, Jensen AMG, Fazeli E, Klein J, Merchant K, Andersen OM.   +7 more
europepmc   +1 more source

The P2X4 purinergic receptor controls the autophagy-related release of small extracellular vesicles from mammary cancer cells under hypoxia. [PDF]

Cell Commun Signal
Duret T, Elmallah M, Heraud-Meley A, Tessier C, Da Silva AVV, Chadet S, Lemoine R, Gainche J, Labas V, Teixeira-Gomes AP, Tomas D, Cuplov V, Jiang LH, Fan L, Yin G, Baron C, Roger S.   +16 more
europepmc   +1 more source

CNTF specifically slows down the axonal transport of signalling endosomes

Rhymes ER, Sleigh JN, Schiavo G, Tosolini AP.   +3 more
europepmc   +1 more source

The Endosomal Network: Mediators and Regulators of Endosome Maturation. [PDF]

Progress in molecular and subcellular biology, 2018
Endocytosis is a means for the cell to sample its environment for nutrients and regulate plasma membrane (PM) composition and area. Whereas the majority of internalized cargo is recycled back to the cell surface, select material is sent to the lysosome for degradation.
M. Podinovskaia, A. Spang
semanticscholar   +6 more sources

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Rab GTPase Function in Endosome and Lysosome Biogenesis

Trends in Cell Biology, 2018
Eukaryotic cells maintain a highly organized endolysosomal system. This system regulates the protein and lipid content of the plasma membrane, it participates in the intracellular quality control machinery and is needed for the efficient removal of ...
Florian Frohlich, Lars Langemeyer, Christian Ungermann   +2 more
exaly   +2 more sources