Endostatin's endpoints—Deciphering the endostatin antiangiogenic pathway [PDF]
Cancer Cell, 2004 Up until now, the precise mechanism for endostatin's antiangiogenesis action was not known. In a recent report, have taken advantage of gene array and proteomic analysis to map the antiangiogenic pathways turned on by endostatin. This study resolves some of the controversies surrounding endostatin's biology, and provides a new direction to help dissect
Benezra, Robert, Rafii, Shahin
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Prognostic Performance of Peripheral Blood Biomarkers in Identifying Seropositive Individuals at Risk of Developing Clinically Symptomatic Chagas Cardiomyopathy [PDF]
, 2021 Biomarkers for prognosis-based detection of Trypanosoma cruzi-infected patients presenting no clinical symptoms to cardiac Chagas disease (CD) are not available.
Barrientos, Natalia Mariel +7 more
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Gastric Cancer and Angiogenesis: Is VEGF a Useful Biomarker to Assess Progression and Remission? [PDF]
, 2017 Gastric cancer (GC) has high mortality owing to its aggressive nature. Tumor angiogenesis plays an essential role in the growth, invasion, and metastatic spread of GC.
Ladeira, Kátia +3 more
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VEGF receptors on PC12 cells mediate transient activation of ERK1/2 and Akt: comparison of nerve growth factor and vascular endothelial growth factor [PDF]
, 2006 Vascular endothelial growth factor (VEGF) and endostatin are angiogenic and anti-angiogenic molecules, respectively, that have been implicated in neurogenesis and neuronal survival.
BD Ackley +28 more
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Prozeßentwicklung und -optimierung zur Herstellung pharmazeutisch interessanter rekombinanter Proteine am Beispiel des human-identischen Endostatins [PDF]
, 2002 [no ...
Finke, Ralf
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Endostatin expression in a pancreatic cell line is modulated by a TNFα-dependent elastase [PDF]
, 2005 Endostatin, an inhibitor of angiogenesis, is a 20 kDa fragment of the basement membrane protein, collagen XVIII. The formation of endostatin relies upon the action of proteases on collagen XVIII.
A Abdollahi +25 more
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The method of correction of hemorrhagic shock action on the pro- and antioxidant system of the periulceral stomach tissues in an experiment [PDF]
, 2023 The article presents the results of an experimental study about modeling hemorrhagic shock in animals with chronic gastric ulcer and further evaluation of the pro- and antioxidant system in periulceral tissues.
Grebeniuk, D. I. +3 more
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Antiangiogenesis signals by endostatin [PDF]
The FASEB Journal, 2001 ABSTRACT Endostatin is a potent endogenous angiogenesis inhibitor that induces regression of tumors in mice. Neither an extracellular receptor for endostatin nor intracellular signals that result in the regression of tumor vascular beds have been identified.
M, Shichiri, Y, Hirata
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Einsatz kapillarelektrophoretischer Methoden für die Analytik von pharmazeutisch interessanten Substanzen in der biotechnologischen Produktion [PDF]
, 2002 [no ...
Frerichs, Simona
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Tamoxifen and Flaxseed Alter Angiogenesis Regulators in Normal Human Breast Tissue In Vivo [PDF]
, 2011 The incidence of breast cancer is increasing in the Western world and there is an urgent need for studies of the mechanisms of sex steroids in order to develop novel preventive strategies.
A Hajitou +55 more
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