Results 31 to 40 of about 703 (170)

Targeting the microbiota‐miRNA‐protease axis: A new therapeutic avenue in melanoma

The FEBS Journal, EarlyView.
Modulation of extracellular matrix (ECM) turnover is central to melanoma progression and metastasis, driven largely by ECM proteases. This review highlights the epigenetic regulation of ECM proteases by microRNAs and their roles in melanoma growth, invasion, and immune modulation.
Elias N. Katsoulieris, Paraskevi Ioannou, Nikolaos A. Afratis   +2 more
wiley   +1 more source

Novel pathogenic mutations and skin biopsy analysis in Knobloch syndrome [PDF]

, 2009
Purpose: To facilitate future diagnosis of Knobloch syndrome (KS) and better understand its etiology, we sought to identify not yet described COL18A1 mutations in KS patients.
Bagatini, Kelly, Carvalhaes, Lorenza, de Oliveira, Gisele, Gava, Elisandra, Godoi, Paulo, Heljasvaara, Ritva, Kague, Erika, Kitten, Gregory, Oliva, Glaucius, Passos-Bueno, Maria-Rita, Pihlajaniemi, Taina, Suzuki, Oscar, Tu, Hongmin   +12 more
core   +1 more source

Plasma concentrations of angiogenetic factors and angiogenetic inhibitors in patients with ductal pancreatic neoplasms. A pilot study [PDF]

, 2011
The aim of the study was to evaluate the circulating concentrations of vascular endothelial growth factor (VEGF), vascular endothelial growth factor receptor-2 (VEGFR-2), vascular endothelial growth factor-D (VEGF-D) and endostatin in patients with ...
A. Barassi, A. Imbrogno, A. M. Morselli-Labate, D. Fabbri, G. Dogliotti, G. Melzi d'Eril, M. M. Corsi, R. Casadei, R. Corinaldesi, R. Pezzilli   +9 more
core   +1 more source

An update on the landscape of collagen bioactive fragments

The FEBS Journal, EarlyView.
The remodeling of the extracellular matrix releases collagen bioactive fragments, which exert molecular functions and regulate numerous biological processes via several signaling pathways. Here, we summarize the latest findings describing the roles of major bioactive fragments from collagens I, IV, VI, and XVIII in various physiological and ...
Sylvie Ricard‐Blum, Julie Fradette
wiley   +1 more source

Needling Therapy for Burn Injury and Related Complications: A Scoping Review of Experimental and Clinical Studies

International Wound Journal, Volume 23, Issue 2, February 2026.
ABSTRACT Needling therapy may be a novel alternative therapeutic intervention for burn injuries and related complications. This scoping review aimed to comprehensively evaluate the evidence status of needling therapy for burns and their complications. Studies on needling therapy for burns and related complications were retrieved from inception to 1st ...
Sung‐A Kim, Jung Won Kang, Tae‐Hun Kim   +2 more
wiley   +1 more source

Antiangiogenic response after 70% hepatectomy and its relationship with hepatic regeneration and angiogenesis in rats [PDF]

, 2010
Background: The aim of this study was to evaluate the antiangiogenic response and its relation to regeneration and angiogenesis after 70% hepatectomy in a rat model. Methods: Sixty-four Wistar albino rats were included in the study.
Abbasoglu O., Birben, E., Colakoglu, T., Dogrul, A.B., Gedikoglu G., Kosemehmetoglu, K., Yaman, E.   +6 more
core   +1 more source

Progressive Insights into 3D Bioprinting for Corneal Tissue Restoration

Advanced Healthcare Materials, Volume 15, Issue 3, 19 January 2026.
This review explores the potential of 3D bioprinting to replicate the complex structure and function of the human cornea. It highlights key advances in bioink development, printing modalities, and in vivo performance, while addressing current challenges and emerging strategies. The review emphasizes bioprinting's promise to overcome donor shortages and
Ilayda Namli, Deepak Gupta, Yogendra Pratap Singh, Pallab Datta, Muhammad Rizwan, Mehmet Baykara, Ibrahim T. Ozbolat   +6 more
wiley   +1 more source

Utility of Vascular Endothelial Growth Factor Inhibitors in the Treatment of Ovarian Cancer: From Concept to Application [PDF]

, 2012
Despite recent advances in the management of ovarian cancer, it remains the most lethal gynecologic malignancy. Vascular endothelial growth factor (VEGF) has been shown to play a pivotal role in the progression of ovarian cancer leading to the eventual ...
Amini, Afshin, Masoumi Moghaddam, Samar, Morris, David L., Pourgholami, Mohammad H.   +3 more
core   +2 more sources

SMARCA4‐Deficient Undifferentiated Thoracic Tumor: Clinical Features and Prognosis of a Case Series and Literature Review

The Clinical Respiratory Journal, Volume 20, Issue 1, January 2026.
Our manuscript presents detailed presentations of case series of thoracic SMARCA4‐UT, and we report a unique case of diaphragmatic metastases and, interestingly, the occurrence of brain metastasis in one patient, which is a rare phenomenon in SMARCA4‐UT.
Fangzhen Shan, Shuntao Liang, Youwen Zhang, Wei Wu, Guangxia Yang, Mei Yan, Xuemei Zhang, Yumao Miao, Linlin Liu, Jingjing Cai, Zhitao Shi, Bangdong Liu, Nannan Zhang   +12 more
wiley   +1 more source

Endostatin Induces Endothelial Cell Apoptosis [PDF]

Journal of Biological Chemistry, 1999
Endostatin, a carboxyl-terminal fragment of collagen XVIII, has been shown to regress tumors in mice. In this study, we have analyzed the mechanism of endostatin action on endothelial cells and nonendothelial cells. Endostatin treatment of cow pulmonary artery endothelial cells caused apoptosis, as demonstrated by three methods, annexin V-fluorescein ...
M, Dhanabal, R, Ramchandran, M J, Waterman, H, Lu, B, Knebelmann, M, Segal, V P, Sukhatme   +6 more
openaire   +2 more sources