Results 11 to 20 of about 1,372,494 (310)
New molecular mediators in tumor angiogenesis [PDF]
, 2007 Angiogenesis is essential for tumor growth and progression. It has been demonstrated that tumor growth beyond a size 1 to 2 mm3 requires the induction of new vessels.
Beecken, Wolf-Dietrich +2 more
core +1 more source
Substrate stiffness and VE-cadherin mechano-transduction coordinate to regulate endothelial monolayer integrity. [PDF]
, 2017 The vascular endothelium is subject to diverse mechanical cues that regulate vascular endothelial barrier function. In addition to rigidity sensing through integrin adhesions, mechanical perturbations such as changes in fluid shear stress can also ...
Andresen Eguiluz, Roberto C +3 more
core +1 more source
Endothelial Cell Heterogeneity [PDF]
Cold Spring Harbor Perspectives in Medicine, 2003 To review recent advances in the field of endothelial cell heterogeneity, and to apply this knowledge to an understanding of site-specific vasculopathy, including acute lung injury.Published research and review articles in the English language related to endothelial cell biology and endothelial cell heterogeneity.The results of published studies have ...
openaire +3 more sources
Journal of British Surgery, 1991 Abstract Endothelial cell seeding is a technique that has developed over the past 15 years in response to the need for a high performance synthetic vascular graft. This review details our present knowledge of seeding and examines the various problems that have hampered its introduction into clinical practice.
D A, Mosquera, M, Goldman
openaire +4 more sources
Cells, 2014 Rab GTPases are implicated in endosome-to-plasma membrane recycling, but how such membrane traffic regulators control vascular endothelial growth factor receptor 2 (VEGFR2/KDR) dynamics and function are not well understood.
Helen M. Jopling +8 more
doaj +1 more source
Frontiers in Bioengineering and Biotechnology, 2022 Background: Keloid is a disease caused by abnormal proliferation of skin fibres, the causative mechanism of which remains unclear.Method: In this study, endothelial cells of keloids were studied using scRNAseq combined with bulk-RNAseq data from keloids.
Delin Liu +7 more
doaj +1 more source
The LOX-1 Scavenger Receptor and Its Implications in the Treatment of Vascular Disease
Cardiology Research and Practice, 2012 Cardiovascular disease is the leading cause of death. The disease is due to atherosclerosis which is characterized by lipid and fat accumulation in arterial blood vessel walls. A key causative event is the accumulation of oxidised low density lipoprotein
M. W Twigg +3 more
doaj +1 more source
Scavenger Receptor Structure and Function in Health and Disease
Cells, 2015 Scavenger receptors (SRs) are a ‘superfamily’ of membrane-bound receptors that were initially thought to bind and internalize modified low-density lipoprotein (LDL), though it is currently known to bind to a variety of ligands including endogenous ...
Izma Abdul Zani +6 more
doaj +1 more source
Contribution of Piezo2 to endothelium-dependent pain. [PDF]
, 2015 BackgroundWe evaluated the role of a mechanically-gated ion channel, Piezo2, in mechanical stimulation-induced enhancement of hyperalgesia produced by the pronociceptive vasoactive mediator endothelin-1, an innocuous mechanical stimulus-induced ...
Bogen, Oliver +3 more
core +2 more sources
VEGF-A isoforms program differential VEGFR2 signal transduction, trafficking and proteolysis
Biology Open, 2016 Vascular endothelial growth factor A (VEGF-A) binding to the receptor tyrosine kinase VEGFR2 triggers multiple signal transduction pathways, which regulate endothelial cell responses that control vascular development.
Gareth W. Fearnley +11 more
doaj +1 more source