Results 21 to 30 of about 858,060 (266)

Opening of Cx43-formed hemichannels mediates the Ca2+ signaling associated with endothelial cell migration

open access: yesBiology Direct, 2023
Endothelial cell migration is a key process in angiogenesis. Progress of endothelial cell migration is orchestrated by coordinated generation of Ca2+ signals through a mechanism organized in caveolar microdomains.
Hilda Espinoza, Xavier F. Figueroa
doaj   +1 more source

Infections and endothelial cells [PDF]

open access: yesCardiovascular Research, 2003
Systemic infection by various pathogens interacts with the endothelium and may result in altered coagulation, vasculitis and atherosclerosis. Endothelium plays a role in the initiation and regulation of both coagulation and fibrinolysis. Exposure of endothelial cells may lead to rapid activation of coagulation via tissue factor (TF) expression and the ...
Keller, T.T.   +8 more
openaire   +3 more sources

Endothelial cell seeding

open access: yesJournal of Vascular Surgery, 1991
Endothelial cell seeding is the transplantation of vascular endothelial cells to denuded vascular surfaces. Seeding theoretically reduces the probability of graft or vessel thrombosis and of neointimal fibrous hyperplasia. Thus far, clinical seeding trials disclosed modest improvements in patency and the development of hyperplastic anastomotic lesions ...
D A, Mosquera, M, Goldman
openaire   +4 more sources

Single Cell Analysis of Endothelial Cells Identified Organ-Specific Molecular Signatures and Heart-Specific Cell Populations and Molecular Features

open access: yesFrontiers in Cardiovascular Medicine, 2019
Endothelial cells line the inner surface of vasculature and play an important role in normal physiology and disease progression. Although most tissue is known to have a heterogeneous population of endothelial cells, transcriptional differences in organ ...
Wei Feng   +9 more
doaj   +1 more source

An Endothelial Cell Is Not Simply an Endothelial Cell

open access: yesStem Cells and Development
Endothelial cells (ECs) are a multifaceted component of the vascular system with roles in immunity, maintaining tissue fluid balance, and vascular tone. Dysregulation or dysfunction of ECs can have far-reaching implications, leading pathologies ranging from cardiovascular diseases, such as hypertension and atherosclerosis, ischemia, chronic kidney ...
Shiwani Limbu, Kara E. McCloskey
openaire   +2 more sources

Caspases and p38 MAPK regulate endothelial cell adhesiveness for mesenchymal stem cells. [PDF]

open access: yesPLoS ONE, 2013
Mesenchymal stem cells natively circulating or delivered into the blood stream home to sites of injury. The mechanism of mesenchymal stem cell homing to sites of injury is poorly understood.
Irina A Potapova   +2 more
doaj   +1 more source

Organotypic stromal cells impact endothelial cell transcriptome in 3D microvessel networks

open access: yesScientific Reports, 2022
Endothelial cells line all major blood vessels and serve as integral regulators of many functions including vessel diameter, cellular trafficking, and transport of soluble mediators. Despite similar functions, the phenotype of endothelial cells is highly
Matthew B. Curtis   +3 more
doaj   +1 more source

Comparative Analysis of Blood‐Derived Endothelial Cells for Designing Next‐Generation Personalized Organ‐on‐Chips

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
Background Organ‐on‐chip technology has accelerated in vitro preclinical research of the vascular system, and a key strength of this platform is its promise to impact personalized medicine by providing a primary human cell–culture environment where ...
Tanmay Mathur   +2 more
doaj   +1 more source

Clear corneal grafts with subcritical endothelial cell count after 1 year of penetrating keratoplasty

open access: yesTNOA Journal of Ophthalmic Science and Research, 2018
Endothelial cell loss after penetrating keratoplasty leads to graft failure. The critical limit of the endothelial cell count for corneal decompensation is thought to be 700 cells/mm2.
Aruna Kumari R. Gupta   +1 more
doaj   +1 more source

Single-cell transcriptomic analysis of vascular endothelial cells in zebrafish embryos

open access: yesScientific Reports, 2022
Vascular endothelial cells exhibit substantial phenotypic and transcriptional heterogeneity which is established during early embryogenesis. However, the molecular mechanisms involved in establishing endothelial cell diversity are still not well ...
Suman Gurung   +4 more
doaj   +1 more source

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