Results 21 to 30 of about 971,647 (316)

VEGF-A isoform-specific regulation of calcium ion flux, transcriptional activation and endothelial cell migration

open access: yesBiology Open, 2015
Vascular endothelial growth factor A (VEGF-A) regulates many aspects of vascular physiology such as cell migration, proliferation, tubulogenesis and cell-cell interactions. Numerous isoforms of VEGF-A exist but their physiological significance is unclear.
Gareth W. Fearnley   +3 more
doaj   +1 more source

Scavenger Receptors and Their Potential as Therapeutic Targets in the Treatment of Cardiovascular Disease

open access: yesInternational Journal of Hypertension, 2010
Scavenger receptors act as membrane-bound and soluble proteins that bind to macromolecular complexes and pathogens. This diverse supergroup of proteins mediates binding to modified lipoprotein particles which regulate the initiation and progression of ...
Sam L. Stephen   +7 more
doaj   +1 more source

Receptor Tyrosine Kinase Ubiquitination and De-Ubiquitination in Signal Transduction and Receptor Trafficking

open access: yesCells, 2018
Receptor tyrosine kinases (RTKs) are membrane-based sensors that enable rapid communication between cells and their environment. Evidence is now emerging that interdependent regulatory mechanisms, such as membrane trafficking, ubiquitination, proteolysis
William R. Critchley   +5 more
doaj   +1 more source

Prostaglandin E Positively Modulates Endothelial Progenitor Cell Homeostasis: An Advanced Treatment Modality for Autologous Cell Therapy [PDF]

open access: yes, 2009
Aims: The mobilization of endothelial progenitor cells (EPC) and their functioning in postnatal neovascularization are tightly regulated. To identify new modulators of EPC homeostasis, we screened biologically active prostaglandin E compounds for their ...
Hermann, Patrick C.   +6 more
core   +1 more source

Opening of Cx43-formed hemichannels mediates the Ca2+ signaling associated with endothelial cell migration

open access: yesBiology Direct, 2023
Endothelial cell migration is a key process in angiogenesis. Progress of endothelial cell migration is orchestrated by coordinated generation of Ca2+ signals through a mechanism organized in caveolar microdomains.
Hilda Espinoza, Xavier F. Figueroa
doaj   +1 more source

Endothelial Ion Channels and Cell-Cell Communication in the Microcirculation

open access: yesFrontiers in Physiology, 2022
Endothelial cells in resistance arteries, arterioles, and capillaries express a diverse array of ion channels that contribute to Cell-Cell communication in the microcirculation.
William F. Jackson
doaj   +1 more source

Infections and endothelial cells [PDF]

open access: yesCardiovascular Research, 2003
Systemic infection by various pathogens interacts with the endothelium and may result in altered coagulation, vasculitis and atherosclerosis. Endothelium plays a role in the initiation and regulation of both coagulation and fibrinolysis. Exposure of endothelial cells may lead to rapid activation of coagulation via tissue factor (TF) expression and the ...
Keller, T.T.   +8 more
openaire   +3 more sources

Endothelial cell seeding

open access: yesJournal of Vascular Surgery, 1991
Endothelial cell seeding is the transplantation of vascular endothelial cells to denuded vascular surfaces. Seeding theoretically reduces the probability of graft or vessel thrombosis and of neointimal fibrous hyperplasia. Thus far, clinical seeding trials disclosed modest improvements in patency and the development of hyperplastic anastomotic lesions ...
D A, Mosquera, M, Goldman
openaire   +4 more sources

A multiscale hybrid model for pro-angiogenic calcium signals in a vascular endothelial cell [PDF]

open access: yes, 2011
Cytosolic calcium machinery is one of the principal signaling mechanisms by which endothelial cells (ECs) respond to external stimuli during several biological processes, including vascular progression in both physiological and pathological conditions ...
Marco Scianna, Scianna, Marco
core   +1 more source

Single Cell Analysis of Endothelial Cells Identified Organ-Specific Molecular Signatures and Heart-Specific Cell Populations and Molecular Features

open access: yesFrontiers in Cardiovascular Medicine, 2019
Endothelial cells line the inner surface of vasculature and play an important role in normal physiology and disease progression. Although most tissue is known to have a heterogeneous population of endothelial cells, transcriptional differences in organ ...
Wei Feng   +9 more
doaj   +1 more source

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