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Endothelial Cell Heterogeneity [PDF]
To review recent advances in the field of endothelial cell heterogeneity, and to apply this knowledge to an understanding of site-specific vasculopathy, including acute lung injury.Published research and review articles in the English language related to endothelial cell biology and endothelial cell heterogeneity.The results of published studies have ...
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Cancer, a proliferative disease hallmarked by abnormal cell growth and spread, is largely dependent on tumor neoangiogenesis, with evidence of vascular endothelial dysfunction. Novel ways to assess vascular function in cancer include measuring levels of circulating endothelial cells (CEC).
P.K.Y. Goon +4 more
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Endothelial cell migration is a key process in angiogenesis. Progress of endothelial cell migration is orchestrated by coordinated generation of Ca2+ signals through a mechanism organized in caveolar microdomains.
Hilda Espinoza, Xavier F. Figueroa
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Endothelial cells and coagulation [PDF]
AbstractEndothelial cells form a monolayer, which lines blood vessels. They are crucially involved in maintaining blood fluidity and providing controlled vascular hemostasis at sites of injury. Thereby endothelial cells facilitate multiple mechanisms, including both procoagulant and anticoagulant, which must be kept in balance.
Katharina Neubauer, Barbara Zieger
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Vascular endothelial growth factor A (VEGF-A) regulates many aspects of vascular physiology such as cell migration, proliferation, tubulogenesis and cell-cell interactions. Numerous isoforms of VEGF-A exist but their physiological significance is unclear.
Gareth W. Fearnley +3 more
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Scavenger receptors act as membrane-bound and soluble proteins that bind to macromolecular complexes and pathogens. This diverse supergroup of proteins mediates binding to modified lipoprotein particles which regulate the initiation and progression of ...
Sam L. Stephen +7 more
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Receptor tyrosine kinases (RTKs) are membrane-based sensors that enable rapid communication between cells and their environment. Evidence is now emerging that interdependent regulatory mechanisms, such as membrane trafficking, ubiquitination, proteolysis
William R. Critchley +5 more
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Endothelial Ion Channels and Cell-Cell Communication in the Microcirculation
Endothelial cells in resistance arteries, arterioles, and capillaries express a diverse array of ion channels that contribute to Cell-Cell communication in the microcirculation.
William F. Jackson
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Endothelial cell impact on smooth muscle cell properties: role of hemodynamic forces [PDF]
The vascular endothelium is a dynamic cell monolayer located at the interface of the vessel wall and bloodstream, where it regulates the physiological effects of humoral and hemodynamic stimuli on vessel tone and remodelling.
Killeen, Maria T.
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Double-Stranded RNA Attenuates the Barrier Function of Human Pulmonary Artery Endothelial Cells [PDF]
Circulating RNA may result from excessive cell damage or acute viral infection and can interact with vascular endothelial cells. Despite the obvious clinical implications associated with the presence of circulating RNA, its pathological effects on ...
Heinemann, Akos +46 more
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