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Cells in focus: endothelial cell
The International Journal of Biochemistry & Cell Biology, 2002The endothelial cell is thought to arise from the splanchnopleuric mesoderm. Endothelial cells form the inner lining of a blood vessel and provides an anticoagulant barrier between the vessel wall and blood. In addition to its role as a selective permeability barrier, the endothelial cell is a unique multifunctional cell with critical basal and ...
Bauer E, Sumpio +2 more
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New England Journal of Medicine, 2003
Vascular endothelial cells form a lining — one cell thick — for all the blood vessels in the body, providing a critical interface between the vessel itself and blood-borne elements.
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Vascular endothelial cells form a lining — one cell thick — for all the blood vessels in the body, providing a critical interface between the vessel itself and blood-borne elements.
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Journal of Cellular Physiology, 2003
AbstractEndothelial cells play a wide variety of critical roles in the control of vascular function. Indeed, since the early 1980s, the accumulating knowledge of the endothelial cell structure as well as of the functional properties of the endothelial cells shifted their role from a passive membrane or barrier to a complex tissue with complex functions
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AbstractEndothelial cells play a wide variety of critical roles in the control of vascular function. Indeed, since the early 1980s, the accumulating knowledge of the endothelial cell structure as well as of the functional properties of the endothelial cells shifted their role from a passive membrane or barrier to a complex tissue with complex functions
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Role of Endothelial Cell–Cell Junctions in Endothelial Permeability
2011The endothelial barrier separates the inner blood compartment from the surrounding tissues. At the molecular level, adhesion molecules accumulate at the endothelial cell-cell junction and contribute to maintain vascular integrity. An increase in the endothelial permeability is frequently associated with the deregulation of junctional adhesion. Here, we
Armelle, Le Guelte, Julie, Gavard
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Cell biology of endothelial cells
Human Pathology, 1987Endothelial cells are a source of physiologically important molecules synthesized therein and secreted to the blood and/or to the subendothelial extracellular matrix. These molecules participate in formation of platelet and fibrin thrombi (e.g., von Willebrand factor and tissue factor) and contribute to antithrombotic properties of the endothelium (e.g.
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Archives of Internal Medicine, 1987
• This summary provides an overview of some of the new information about the metabolic and regulatory functions of vascular endothelial cells and discusses possible important consequences of endothelial abnormalities in disease. (Arch Intern Med1987;147:569-573)
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• This summary provides an overview of some of the new information about the metabolic and regulatory functions of vascular endothelial cells and discusses possible important consequences of endothelial abnormalities in disease. (Arch Intern Med1987;147:569-573)
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Journal of the American Society of Hypertension, 2012
Endothelial dysfunction, the shift from a healthy endothelium to a damaged pro-coagulative, pro-inflammatory, and pro-vasoconstrictive phenotype, is an early event in many chronic diseases that frequently precedes cardiovascular complications. Functional assessment of the endothelium can identify endothelial damage and predict cardiovascular risk ...
Dylan, Burger, Rhian M, Touyz
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Endothelial dysfunction, the shift from a healthy endothelium to a damaged pro-coagulative, pro-inflammatory, and pro-vasoconstrictive phenotype, is an early event in many chronic diseases that frequently precedes cardiovascular complications. Functional assessment of the endothelium can identify endothelial damage and predict cardiovascular risk ...
Dylan, Burger, Rhian M, Touyz
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Circulating Endothelial Cells and Circulating Endothelial Progenitors
2012The roles of circulating endothelial cells (CECs) and circulating endothelial progenitors (CEPs) are currently being investigated in several diseases including cancer and metastases development. Preclinical and clinical data suggest that CEC enumeration might be useful to identify patients who might benefit from anti-angiogenic treatments while CEPs ...
Patrizia, Mancuso +2 more
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Heparin-Endothelial Cell Interactions
Pathophysiology of Haemostasis and Thrombosis, 1990Recent observations have revealed that heparin influences endothelial cell proliferation in a number of ways unrelated to its anticoagulant properties. A majority of the nonanticoagulant actions of heparin on the endothelium appear to be related to heparin interactions with the fibroblast growth factors (FGFs).
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