Results 11 to 20 of about 451,622 (253)

Excessive corneal endothelial single-cell loss following endothelial injuries

Taiwan Journal of Ophthalmology
PURPOSE: The purpose of this study was to investigate corneal endothelial changes following common clinical endothelial injury scenarios in order to uncover mechanisms underlying unexplained chronic corneal endothelial wound healing.
Yuan-Kai Fu, Matthew Lin, Kuo-Hsuan Hung, Lung-Kun Yeh, Hsin-Yuan Tan   +4 more
doaj   +3 more sources

Nuclear SUN1 stabilizes endothelial cell junctions via microtubules to regulate blood vessel formation

eLife, 2023
Endothelial cells line all blood vessels, where they coordinate blood vessel formation and the blood-tissue barrier via regulation of cell-cell junctions.
Danielle B Buglak, Pauline Bougaran, Molly R Kulikauskas, Ziqing Liu, Elizabeth Monaghan-Benson, Ariel L Gold, Allison P Marvin, Andrew Burciu, Natalie T Tanke, Morgan Oatley, Shea N Ricketts, Karina Kinghorn, Bryan N Johnson, Celia E Shiau, Stephen Rogers, Christophe Guilluy, Victoria L Bautch   +16 more
doaj   +1 more source

Comparison of Changes in Endothelial Corneal Cell Count of Vitrectomized Silicone Oil-Filled Eyes

Pakistan Armed Forces Medical Journal, 2023
Objective: To determine the mean endothelial cell change in patients undergoing vitrectomy with silicon oil replacement and to compare the corneal endothelial cell loss frequency of phakic, pseudophakic, and aphakic Vitrectomized Silicone Oil-filled ...
Abdul Hannan, Sarah Zafar, Aziz Jan Bashir, Hassan Massana, Kashif Habib, Abdullah Naeem   +5 more
doaj   +1 more source

Comparison of corneal endothelial cell loss in FLACS: impact on endothelial cells in different regions. [PDF]

J Cataract Refract Surg
Purpose: To compare changes in corneal endothelial parameters after femtosecond laser–assisted cataract surgery (FLACS) and conventional phacoemulsification surgery (CPS) in different corneal regions. Setting: Chang Gung Memorial Hospital, Linkou, Taiwan.
Altansukh A, Ma KS, Doyodmaa A, Hung N, Kang EY, Quan W, Ma DH.   +6 more
europepmc   +3 more sources

Loss of PPARγ in endothelial cells leads to impaired angiogenesis [PDF]

Journal of Cell Science, 2016
Tie2 promoter-mediated loss of peroxisome proliferator-activated receptor gamma (PPARγ) in mice leads to osteopetrosis and pulmonary arterial hypertension. Vascular disease is associated with loss of PPARγ in pulmonary microvascular endothelial cells (PMVEC), we evaluated the role of PPARγ in PMVEC functions, such as angiogenesis and migration.
Vattulainen-Collanus S, Akinrinade, O, Li, ML, Koskenvuo, M, Li, CG, Rao, SP, Perez, VD, Yuan, K, Sawada, H, Koskenvuo, JW, Alvira, C, Rabinovitch, M, Alastalo, TP   +12 more
openaire   +2 more sources

Targeted Thrombospondin-1 Expression in Ocular Vascular Development and Neovascularization

Frontiers in Cell and Developmental Biology, 2021
Tight regulation of positive and negative regulators of angiogenesis is essential, particularly in the eye where their dysregulation can lead to vision loss.
Christine M. Sorenson, Christine M. Sorenson, Shoujian Wang, Soesiawati R. Darjatmoko, Zafer Gurel, Bo Liu, Bo Liu, Nader Sheibani, Nader Sheibani, Nader Sheibani, Nader Sheibani   +10 more
doaj   +1 more source

Loss ofPim1Imposes a Hyperadhesive Phenotype on Endothelial Cells [PDF]

Cellular Physiology and Biochemistry, 2012
Background: PIM1 is a constitutively active serine-threonine kinase regulating cell survival and proliferation. Increased PIM1 expression has been correlated with cancer metastasis by facilitating migration and anti-adhesion. Endothelial cells play a pivotal role in these processes by contributing a barrier to the blood stream.
Walpen, Thomas, Peier, Martin, Haas, Elvira, Kalus, Ina, Schwaller, Jürg, Battegay, Edouard, Humar, Rok   +6 more
openaire   +5 more sources

Effect of Mitomycin-C augmented trabeculectomy on corneal endothelial cells

Journal of Ophthalmic & Vision Research, 2015
Purpose: To evaluate the effect of mitomycin-C (MMC) on corneal endothelial cell density (ECD) and morphology after trabeculectomy. Methods: In this prospective comparative case series, 31 eyes with glaucoma underwent trabeculectomy with (group I), or ...
Reza Zarei, Mohammad Zarei, Ghasem Fakhraie, Yadollah Eslami, Sasan Moghimi, Masoud Mohammadi, Ali Abdollahi   +6 more
doaj   +1 more source

Prospective cohort study of corneal endothelial cell loss after Baerveldt glaucoma implantation. [PDF]

PLoS ONE, 2018
PURPOSE:To evaluate corneal endothelial cell loss after Baerveldt glaucoma implantation. METHODS:We prospectively evaluated changes in endothelial cell density (ECD) in the cornea of 59 patients (59 eyes) who underwent Baerveldt glaucoma implantation ...
Kentaro Iwasaki, Shogo Arimura, Yuji Takihara, Yoshihiro Takamura, Masaru Inatani   +4 more
doaj   +1 more source

Diagnostic Techniques to Increase the Safety of Phakic Intraocular Lenses

Diagnostics, 2023
Preoperative and postoperative diagnostics play an important role in ensuring the safety of patients with phakic intraocular lenses (pIOLs). The risk of endothelial cell loss can be addressed by regularly measuring the endothelial cell density using ...
Tadas Naujokaitis, Gerd U. Auffarth, Grzegorz Łabuz, Lucy Joanne Kessler, Ramin Khoramnia   +4 more
doaj   +1 more source