Results 21 to 30 of about 1,470,142 (341)

Profiling the mouse brain endothelial transcriptome in health and disease models reveals a core blood-brain barrier dysfunction module. [PDF]

, 2019
Blood vessels in the CNS form a specialized and critical structure, the blood-brain barrier (BBB). We present a resource to understand the molecular mechanisms that regulate BBB function in health and dysfunction during disease.
Aydin, Sidar, Batugal, Austin, Cabangcala, Anne Christelle, Daneman, Richard, Gimlin, Kayleen, Hashimoto, Tomoki, Korai, Masaaki, Kotoda, Masakazu, Munji, Roeben Nocon, Noble-Haeusslein, Linda J, Oldham, Michael Clark, Schupp, Patrick Georg, Semple, Bridgette Deanne, Sohet, Fabien, Soung, Allison Luen, Trivedi, Alpa, Weiner, Geoffrey Aaron   +16 more
core   +1 more source

Identification and antioxidative mechanism of novel mitochondria-targeted MFG-E8 polypeptides in virtual screening and in vitro study

Journal of Dairy Science, 2023
: Milk fat globule-EGF factor VIII (MFG-E8) has been identified as an important source of bioactive peptides, which may exert a pivotal role in regulating biologic redox equilibrium. However, the composition of MFG-E8 polypeptides and their mechanisms on
Kaifang Guan, He Li, DanDan Liu, Min Liu, Canxia He   +4 more
doaj  

Comparative Analysis of Blood‐Derived Endothelial Cells for Designing Next‐Generation Personalized Organ‐on‐Chips

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
Background Organ‐on‐chip technology has accelerated in vitro preclinical research of the vascular system, and a key strength of this platform is its promise to impact personalized medicine by providing a primary human cell–culture environment where ...
Tanmay Mathur, James J. Tronolone, Abhishek Jain   +2 more
doaj   +1 more source

Sirtuin1 protects endothelial Caveolin-1 expression and preserves endothelial function via suppressing miR-204 and endoplasmic reticulum stress. [PDF]

, 2017
Sirtuin1 (Sirt1) is a class III histone deacetylase that regulates a variety of physiological processes, including endothelial function. Caveolin1 (Cav1) is also an important determinant of endothelial function. We asked if Sirt1 governs endothelial Cav1
Gabani, Mohanad, Irani, Kaikobad, Jacobs, Julia S, Kassan, Adam, Kassan, Modar, Kim, Young-Rae, Kumar, Santosh, Li, Qiuxia, Liu, Jing, Patel, Hemal H, Vikram, Ajit   +10 more
core   +3 more sources

Endothelial Cell Dysfunction and Nonalcoholic Fatty Liver Disease (NAFLD): A Concise Review

Cells, 2022
Nonalcoholic fatty liver disease (NAFLD) is one of the most common liver diseases worldwide. It is strongly associated with obesity, type 2 diabetes (T2DM), and other metabolic syndrome features.
Narjes Nasiri-Ansari, Theodoros Androutsakos, Christina-Maria Flessa, Ioannis Kyrou, Gerasimos Siasos, Harpal S. Randeva, Eva Kassi, Athanasios G. Papavassiliou   +7 more
doaj   +1 more source

Caspases and p38 MAPK regulate endothelial cell adhesiveness for mesenchymal stem cells. [PDF]

PLoS ONE, 2013
Mesenchymal stem cells natively circulating or delivered into the blood stream home to sites of injury. The mechanism of mesenchymal stem cell homing to sites of injury is poorly understood.
Irina A Potapova, Ira S Cohen, Sergey V Doronin   +2 more
doaj   +1 more source

Endothelial Cell Heterogeneity [PDF]

Cold Spring Harbor Perspectives in Medicine, 2003
To review recent advances in the field of endothelial cell heterogeneity, and to apply this knowledge to an understanding of site-specific vasculopathy, including acute lung injury.Published research and review articles in the English language related to endothelial cell biology and endothelial cell heterogeneity.The results of published studies have ...
openaire   +4 more sources

High Glucose, But Not Testosterone, Increases Platelet Aggregation Mediated by Endothelial Cells [PDF]

, 2015
Endothelial cells inhibit platelet aggregation by releasing thromboregulators, such as prostacyclin and nitric oxide. Male subject is a traditional risk factor for cardiovascular diseases.
Aswin, S. (Soedjono), Jenie, I. M. (Ikhlas), Mulyono, B. (Budi), Soejono, S. K. (Sri)   +3 more
core   +2 more sources

No Differences in Levels of Circulating Progenitor Endothelial Cells or Circulating Endothelial Cells Among Patients Treated With Ticagrelor Compared With Clopidogrel During Non–ST‐Segment–Elevation Myocardial Infarction

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
Background Ticagrelor use during acute coronary syndromes demonstrated a decrease in all‐cause mortality in the PLATO (Platelet Inhibition and Patient Outcomes) trial.
Alejandro Diego‐Nieto, Maria B. Vidriales, Norberto Alonso‐Orcajo, Jose C. Moreno‐Samos, Francisco Martin‐Herrero, Raul Carbonell, Belen Cid, Ignacio Cruz‐Gonzalez, Javier C. Martin‐Moreiras, Carlos Cuellas, Cristina Pascual, Maria Lopez‐Benito, Pedro L. Sanchez, Felipe Fernandez‐Vazquez, Armando Perez de Prado   +14 more
doaj   +1 more source

Ox-LDL induced profound changes of small non-coding RNA in rat endothelial cells

Frontiers in Cardiovascular Medicine, 2023
IntroductionAtherosclerosis (AS) is a common cardiovascular disease with a high incidence rate and mortality. Endothelial cell injury and dysfunction are early markers of AS.
Yu Wang, Tianhua Liu, Wenying Xiao, Yanyan Bai, Dandan Yue, Liuliu Feng   +5 more
doaj   +1 more source