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Endothelial Dysfunction in Hypertension
Journal of Cardiovascular Pharmacology, 2001Endothelium can deeply influence vascular tone and structure. The main endothelium derived factor is nitric oxide, which is not only a potent vasodilator but also inhibits platelet aggregation, smooth muscle cell migration and proliferation, monocyte adhesion and adhesion molecule expression, thus protecting the vessel wall against the development of ...
TADDEI, STEFANO +4 more
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Endothelial dysfunction in hypertension.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1997link_to_subscribed_fulltext
TADDEI, STEFANO, SALVETTI, ANTONIO
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2015
The hypothesis that preeclampsia phenotypes result from endothelial cell dysfunction has been followed by decades of evidence demonstrating vascular dysfunction and augmented vascular reactivity in preeclampsia. Multiple studies have detected biomarkers of endothelial activation prior to overt disease.
Davidge, Sandra T. +2 more
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The hypothesis that preeclampsia phenotypes result from endothelial cell dysfunction has been followed by decades of evidence demonstrating vascular dysfunction and augmented vascular reactivity in preeclampsia. Multiple studies have detected biomarkers of endothelial activation prior to overt disease.
Davidge, Sandra T. +2 more
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ED2: Erectile Dysfunction = Endothelial Dysfunction
Endocrinology and Metabolism Clinics of North America, 2007Erectile dysfunction (ED) is a common condition in men, and increases with age. Cardiovascular disease (CVD) is the leading cause of death in men and also increases in prevalence with advancing years. The common link between the two conditions is endothelial dysfunction that leads to vascular insufficiency of the coronary and penile arteries.
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Assessment of endothelial dysfunction
Expert Review of Cardiovascular Therapy, 2010The pathophysiology underlying the initiation and progression of cardiovascular disorders is highly complex and multifactorial. The endothelium also plays a crucial role in the pathogenesis of thrombogenesis and atherogenesis, and a continuum of endothelial activation, dysfunction or damage is evident in many cardiovascular disorders both at the macro ...
Bethan, Freestone +2 more
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Hypercholesterolemia and endothelial dysfunction
Current Opinion in Lipidology, 1995Endothelial cells respond to hemodynamic forces with the expression of different phenotypes with disparate functional properties. At arterial bends and flow dividers, cells are relatively deprived of fluid-shear-stress-induced cell differentiation and exhibit phenotypes with increased mitotic rate, decreased intercellular contact, increased ...
P D, Henry, O A, Cabello, C H, Chen
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Statins and Endothelial Dysfunction
Seminars in Vascular Medicine, 2004The endothelium integrates and modulates critical functions of the arterial wall. As well as regulating vasomotion, it controls inflammation, coagulation, and thrombosis. Many of these actions are mediated through the release of nitric oxide. Endothelial dysfunction is associated with atherosclerosis and its risk factors. It is independently correlated
Eric, Larose, Peter, Ganz
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Endothelial Dysfunction and Hypertension
2016In the past, endothelium was thought to be only a mechanical barrier. Today, endothelium is known to be a tissue regulating vascular tone, cell growth and the interaction between the leukocytes, thrombocytes and the vessel wall. It also synthesizes growth factors and thrombo-regulatory molecules and responds to physical and chemical signals.
Dildar, Konukoglu, Hafize, Uzun
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Endothelial dysfunction in glaucoma
Acta Ophthalmologica, 2009Abstract.Glaucoma is a group of ocular diseases characterized by optic neuropathy associated with loss of the retinal nerve fibre layer and re‐modelling of the optic nerve head, and a subsequent particular pattern of visual field loss. Increased intraocular pressure is the most important risk factor for the disease, but the pathogenesis of glaucoma is ...
Hemma, Resch +4 more
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Orvosi hetilap, 2002
The endothelium is a major regulator of vascular tone, releasing vasoconstrictive (endothelin, cyclooxigenase-dependent factors, including prostanoids and oxygen free radicals) and vasodilating (endothelium--derived nitric oxid, endothelium--derived hyperpolarizing factor) mediators.
J, Nagy +3 more
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The endothelium is a major regulator of vascular tone, releasing vasoconstrictive (endothelin, cyclooxigenase-dependent factors, including prostanoids and oxygen free radicals) and vasodilating (endothelium--derived nitric oxid, endothelium--derived hyperpolarizing factor) mediators.
J, Nagy +3 more
openaire +1 more source

