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Endothelial Dysfunction in Hypertension

Journal of Cardiovascular Pharmacology, 2001
Endothelium can deeply influence vascular tone and structure. The main endothelium derived factor is nitric oxide, which is not only a potent vasodilator but also inhibits platelet aggregation, smooth muscle cell migration and proliferation, monocyte adhesion and adhesion molecule expression, thus protecting the vessel wall against the development of ...
TADDEI, STEFANO   +4 more
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Endothelial dysfunction in hypertension.

Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1997
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TADDEI, STEFANO, SALVETTI, ANTONIO
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Endothelial Cell Dysfunction

2015
The hypothesis that preeclampsia phenotypes result from endothelial cell dysfunction has been followed by decades of evidence demonstrating vascular dysfunction and augmented vascular reactivity in preeclampsia. Multiple studies have detected biomarkers of endothelial activation prior to overt disease.
Davidge, Sandra T.   +2 more
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ED2: Erectile Dysfunction = Endothelial Dysfunction

Endocrinology and Metabolism Clinics of North America, 2007
Erectile dysfunction (ED) is a common condition in men, and increases with age. Cardiovascular disease (CVD) is the leading cause of death in men and also increases in prevalence with advancing years. The common link between the two conditions is endothelial dysfunction that leads to vascular insufficiency of the coronary and penile arteries.
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Assessment of endothelial dysfunction

Expert Review of Cardiovascular Therapy, 2010
The pathophysiology underlying the initiation and progression of cardiovascular disorders is highly complex and multifactorial. The endothelium also plays a crucial role in the pathogenesis of thrombogenesis and atherogenesis, and a continuum of endothelial activation, dysfunction or damage is evident in many cardiovascular disorders both at the macro ...
Bethan, Freestone   +2 more
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Hypercholesterolemia and endothelial dysfunction

Current Opinion in Lipidology, 1995
Endothelial cells respond to hemodynamic forces with the expression of different phenotypes with disparate functional properties. At arterial bends and flow dividers, cells are relatively deprived of fluid-shear-stress-induced cell differentiation and exhibit phenotypes with increased mitotic rate, decreased intercellular contact, increased ...
P D, Henry, O A, Cabello, C H, Chen
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Statins and Endothelial Dysfunction

Seminars in Vascular Medicine, 2004
The endothelium integrates and modulates critical functions of the arterial wall. As well as regulating vasomotion, it controls inflammation, coagulation, and thrombosis. Many of these actions are mediated through the release of nitric oxide. Endothelial dysfunction is associated with atherosclerosis and its risk factors. It is independently correlated
Eric, Larose, Peter, Ganz
openaire   +2 more sources

Endothelial Dysfunction and Hypertension

2016
In the past, endothelium was thought to be only a mechanical barrier. Today, endothelium is known to be a tissue regulating vascular tone, cell growth and the interaction between the leukocytes, thrombocytes and the vessel wall. It also synthesizes growth factors and thrombo-regulatory molecules and responds to physical and chemical signals.
Dildar, Konukoglu, Hafize, Uzun
openaire   +2 more sources

Endothelial dysfunction in glaucoma

Acta Ophthalmologica, 2009
Abstract.Glaucoma is a group of ocular diseases characterized by optic neuropathy associated with loss of the retinal nerve fibre layer and re‐modelling of the optic nerve head, and a subsequent particular pattern of visual field loss. Increased intraocular pressure is the most important risk factor for the disease, but the pathogenesis of glaucoma is ...
Hemma, Resch   +4 more
openaire   +2 more sources

[Endothelial dysfunction].

Orvosi hetilap, 2002
The endothelium is a major regulator of vascular tone, releasing vasoconstrictive (endothelin, cyclooxigenase-dependent factors, including prostanoids and oxygen free radicals) and vasodilating (endothelium--derived nitric oxid, endothelium--derived hyperpolarizing factor) mediators.
J, Nagy   +3 more
openaire   +1 more source

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